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Effects of left ventricular pacing on cardiac performance and on quality of life in patients with drug refractory heart failure

      Previous hemodynamic studies have shown that both left ventricular (LV) and biventricular pacing results in similar and significant improvement of LV function in a selected population of patients with depressed systolic function and left bundle branch block (LBBB).
      • Blanc J.J
      • Etienne Y
      • Gilard M
      • Mansourati J
      • Munier S
      • Boschat J
      • Benditt D
      Evaluation of different ventricular pacing sites in patients with severe heart failure. Results of an acute hemodinamic study.
      ,
      • Leclercq C
      • Cazeau S
      • Le Breton H
      • Ritter P
      • Mabo P
      • Gras D
      • Pavin D
      • Lazarus A
      • Daubert J.C
      Acute hemodynamic effects of biventricular DDD pacing in patients with end-stage heart failure.
      ,
      • Etienne Y
      • Mansurati J
      • Gilard M
      • Valls-Bertauld V
      • Boschat J
      • Benditt D
      • Lurie K
      • Blanc J.J
      Evaluation of left ventricular based pacing in patients with congestive heart failure and atrial fibrillation.
      ,
      • Kass D.A
      • Chen C
      • Curry C
      • Talbot M
      • Berger R
      • Fetics B
      • Nevo E
      Improved left ventricular mechanics from acute VDD pacing in patients with dilated cardiomyopathy and ventricular conduction delay.
      ,
      • Auricchio A
      • Stellbrink C
      • Block M
      • Sack S
      • Vogt J
      • Bakker P
      • Klein H
      Effect of pacing chamber and atriventricular delay on acute systolic function of paced patients with congestive heart failure.
      According to the actual understanding of mechanism of pacing in heart failure, pacing resynchronizes the delayed portion of the ventricle, bypassing the site of block. We performed a controlled evaluation of the acute and medium-term effects of this new pacing modality on cardiac performance and quality of life.
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      References

        • Blanc J.J
        • Etienne Y
        • Gilard M
        • Mansourati J
        • Munier S
        • Boschat J
        • Benditt D
        Evaluation of different ventricular pacing sites in patients with severe heart failure. Results of an acute hemodinamic study.
        Circulation. 1997; 96: 3273-3277
        • Leclercq C
        • Cazeau S
        • Le Breton H
        • Ritter P
        • Mabo P
        • Gras D
        • Pavin D
        • Lazarus A
        • Daubert J.C
        Acute hemodynamic effects of biventricular DDD pacing in patients with end-stage heart failure.
        J Am Coll Cardiol. 1998; 32: 1825-1831
        • Etienne Y
        • Mansurati J
        • Gilard M
        • Valls-Bertauld V
        • Boschat J
        • Benditt D
        • Lurie K
        • Blanc J.J
        Evaluation of left ventricular based pacing in patients with congestive heart failure and atrial fibrillation.
        Am J Cardiol. 1999; 83: 1138-1140
        • Kass D.A
        • Chen C
        • Curry C
        • Talbot M
        • Berger R
        • Fetics B
        • Nevo E
        Improved left ventricular mechanics from acute VDD pacing in patients with dilated cardiomyopathy and ventricular conduction delay.
        Circulation. 1999; 99: 1567-1573
        • Auricchio A
        • Stellbrink C
        • Block M
        • Sack S
        • Vogt J
        • Bakker P
        • Klein H
        Effect of pacing chamber and atriventricular delay on acute systolic function of paced patients with congestive heart failure.
        Circulation. 1999; 99: 2993-3001
        • Rector T.S
        • Kubo S.H
        • Cohn J.N
        Patients’ self-assessment of their congestive heart failure..
        Heart Failure. 1987; 3: 198-209
        • Opasich C
        • Pinna D
        • Mazza A
        • Febo O
        • Riccardi G
        • Capomolla S
        • Cobelli F
        • Tavazzi L
        Reproducibility of the six-minute walking test in patients with chronic congestive heart failure.
        Am J Cardiol. 1998; 81: 1497-1500
        • Gras D
        • Cazeau S
        • Ritter P
        • Tang A
        • Mabo P
        • Kirstein-Pedersen A
        • Bucknall C
        • Luttikhuis H.O
        • et al.
        Long term results of cardiac resynchronization for heart failure patients.
        Circulation. 1999; 100 (abstr): I515
        • Tang A
        • Gras D
        • Mabo P
        • Bucknall C
        • Luttikhuis H.O
        • Kirstein-Pedersen A
        • Van Trig A
        • Hill M
        Mortality and outcome differences between survivors and unsurvivors in the InSynch cardiac resynchronization trial.
        Circulation. 1999; 100 (abstr): I515
        • Brignole M
        • Menozzi C
        • Gianfranchi L
        • Musso G
        • Mureddu R
        • Bottoni N
        • Lolli G
        Assessment of atrioventricular junction ablation and VVIR pacemaker versus pharmacological treatment in patients with heart failure and chronic atrial fibrillation. A randomized controlled study.
        Circulation. 1998; 98: 953-960