Dr. Michel Mirowski, the inventor of the implantable cardioverter defibrillator (ICD),
envisioned it as a prophylactic device for primary prevention of sudden cardiac death
(SCD).
1
However, it was appropriate to first demonstrate the safety and efficacy of the ICD
in secondary prevention of SCD in patients with known life-threatening sustained ventricular
tachycardia (VT-S) or ventricular fibrillation (VF). By the end of the first decade
of ICD therapy, its efficacy in virtually eliminating SCD due to VT/VF was well established,
2
,
3
opening the door to investigations into the role of the ICD as a primary prophylaxis.
4
,
5
,
6
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References
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- Prevention of sudden death in patients with coronary artery disease.Prog Cardiovasc Disease. 1993; 36: 215-226
- Prevalence and prognostic significance of ventricular arrhythmias after acute myocardial infarction in the fibrinolytic era.Circulation. 1993; 87: 312-322
- Are there subgroups of patients at high risk for sudden death and cardiac arrest without inducible sustained monomorphic ventricular tachycardia—results from the Multicenter UnSustained Tachycardia Trial (MUSTT).Circulation. 1999; 100 (abstr): I81
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Article info
Publication history
Published online: August 16, 2004
Accepted:
June 8,
2000
Received:
June 8,
2000
Identification
Copyright
© 2000 Excerpta Medica Inc. Published by Elsevier Inc. All rights reserved.
