Abstract
Diffuse coronary artery disease (CAD) is considered unfavorable for interventional
procedures; however, the results of stenting of diffuse CAD have not been completely
characterized. We performed stenting in 100 consecutive patients with diffuse CAD,
defined as significant stenosis >20 mm (n = 59 patients), multiple significant stenoses
in the same artery (n = 23 patients), or significant narrowing involving the whole
length of the coronary artery (n = 18 patients). Angiographic success was achieved
in 103 arteries (100%) and clinical success was obtained in all 100 patients. There
were no deaths; no patient had stent closure, acute myocardial infarction, or required
emergency coronary artery bypass surgery. All 100 patients had >6 months follow-up
(mean 18 ± 7 months, range 7 to 31); 77 (77%) remained asymptomatic, and 5 (5%) had
acute myocardial infarction, of whom 2 died (2%). In-stent restenosis was observed
in 12 patients (12%) and repeat angioplasty was performed in 10. Including those patients
who underwent repeat angioplasty, 89 (89%) maintained clinical improvement and 95
(95%) were alive and free of bypass surgery during follow-up. Life-table analysis
showed 86% freedom from death, myocardial infarction, and target lesion revascularization
at 28 months. Thus, selected patients with diffuse CAD may be treated with satisfactory
acute and long-term results by stent implantation.
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Article info
Publication history
Published online: August 16, 2004
Accepted:
June 5,
2000
Received in revised form:
June 5,
2000
Received:
January 18,
2000
Identification
Copyright
© 2000 Excerpta Medica Inc. Published by Elsevier Inc. All rights reserved.
