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Comparison of clinical features in patients ≥60 years of age to those ≤40 years of age with hypertrophic cardiomyopathy

  • Taishiro Chikamori
    Affiliations
    From the Department of Cardiological Sciences, St. George's Hospital Medical School, Cranmer Terrace, London SW17 ORE, United Kingdom

    From the Department of Medicine and Geriatrics, Kochi Medical School, Kochi, Japan
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  • Yoshinori L. Doi
    Affiliations
    From the Department of Cardiological Sciences, St. George's Hospital Medical School, Cranmer Terrace, London SW17 ORE, United Kingdom

    From the Department of Medicine and Geriatrics, Kochi Medical School, Kochi, Japan
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  • Yoshihiro Yonezawa
    Affiliations
    From the Department of Cardiological Sciences, St. George's Hospital Medical School, Cranmer Terrace, London SW17 ORE, United Kingdom

    From the Department of Medicine and Geriatrics, Kochi Medical School, Kochi, Japan
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  • Shaughan Dickie
    Affiliations
    From the Department of Cardiological Sciences, St. George's Hospital Medical School, Cranmer Terrace, London SW17 ORE, United Kingdom

    From the Department of Medicine and Geriatrics, Kochi Medical School, Kochi, Japan
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  • Toshio Ozawa
    Affiliations
    From the Department of Cardiological Sciences, St. George's Hospital Medical School, Cranmer Terrace, London SW17 ORE, United Kingdom

    From the Department of Medicine and Geriatrics, Kochi Medical School, Kochi, Japan
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  • William J. McKenna
    Affiliations
    From the Department of Cardiological Sciences, St. George's Hospital Medical School, Cranmer Terrace, London SW17 ORE, United Kingdom

    From the Department of Medicine and Geriatrics, Kochi Medical School, Kochi, Japan
    Search for articles by this author
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      Abstract

      The diagnosis of hypertrophie cardiomyopathy (HC) is based on the demonstration of unexplained left ventricular hypertrophy and may follow the development of symptoms or represent an incidental finding during routine examination from infancy to the grave. The natural history is characterized by a slow progression of symptoms and a high incidence of sudden death.1 In most clinical and prognostic studies, the majority of patients are aged 18 to 60.2–4 Though diagnosis and morphological features of HC in the elderly have been emphasized recently, detailed clinical features and left ventricular function have not been reported.5–9 We compared clinical features in elderly patients with those in the young and also evaluated the influence of age on indexes of systolic and diastolic function derived from equilibrium radionuclide angiography in HC.
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