Creatine kinase-MB activity after implantation of a cardiac pacemaker

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      Identification of creatine kinase (CK) isoenzyme CK-MB has made an excellent improvement of the diagnosis of myocardial infarction.1 Cardiac muscle contains relatively large amounts of CK-MB. CK-MB is also present in skeletal muscle. Injury to skeletal muscle may therefore result in elevation of “non-cardiac” CK-MB and cause difficulties in the diagnosis of myocardial infarction.2,3 Elevation of CK-MB may also be expected in direct cardiac muscle injury, but previous studies reflecting this relation have shown only a slight increase in CK-MB isoenzyme activity.4 This study evaluates total CK and isoenzyme CK-MB activity in patients undergoing cardiac pacemaker implantation. In this procedure there is injury to cardiac and skeletal muscle.
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        • Roberts R
        • Gowda KS
        • Ludbrook PA
        • Sobel BE
        Specificity of elevated serum MB creatine phosphokinase activity in the diagnosis of acute myocardial infarction.
        Am J Cardiol. 1975; 36: 433-437
        • Tsung SH
        Several conditions causing elevation of serum CK-MB and CK-BB.
        Am J Cardiol. 1981; 75: 711-715
        • Jaffee AS
        • Garfinkel BT
        • Ritter CS
        • Sobel BE
        Plasma MB creatine kinase after vigorous exercise in professional athletes.
        Am J Cardiol. 1984; 53: 856-858
        • Rosenblum AM
        • Ludbrook PA
        • Jaffe AS
        Significance of elevated MB creatine kinase in patients after cardiac catheterization.
        Cathet Cardiovasc Diagn. 1984; 10: 547-552
        • Gerhardt W
        • Waldenstrøm J
        Creatine kinase B-subunit activity in serum after immunoinhibition of M-subunit activity.
        Clin Chem. 1979; 25: 1274-1280