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Exercise, electrocardiographic and functional responses after percutaneous transluminal coronary angioplasty

  • Douglas R. Rosing
    Correspondence
    Address for reprints: Douglas R. Rosing, MD, National Institutes of Health, Building 10 Room 7B-15, Bethesda, Maryland 20205.
    Affiliations
    From the National Institutes of Health, Bethesda, Maryland USA

    From the University of Pittsburgh, Pittsburgh, Pennsylvania USA

    From the Montreal Heart Institute, Montreal, Quebec, Canada
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  • Mark J. Van Raden
    Affiliations
    From the National Institutes of Health, Bethesda, Maryland USA

    From the University of Pittsburgh, Pittsburgh, Pennsylvania USA

    From the Montreal Heart Institute, Montreal, Quebec, Canada
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  • Rita M. Mincemoyer
    Affiliations
    From the National Institutes of Health, Bethesda, Maryland USA

    From the University of Pittsburgh, Pittsburgh, Pennsylvania USA

    From the Montreal Heart Institute, Montreal, Quebec, Canada
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  • Robert O. Bonow
    Affiliations
    From the National Institutes of Health, Bethesda, Maryland USA

    From the University of Pittsburgh, Pittsburgh, Pennsylvania USA

    From the Montreal Heart Institute, Montreal, Quebec, Canada
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  • Martial G. Bourassa
    Affiliations
    From the National Institutes of Health, Bethesda, Maryland USA

    From the University of Pittsburgh, Pittsburgh, Pennsylvania USA

    From the Montreal Heart Institute, Montreal, Quebec, Canada
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  • Paul R. David
    Affiliations
    From the National Institutes of Health, Bethesda, Maryland USA

    From the University of Pittsburgh, Pittsburgh, Pennsylvania USA

    From the Montreal Heart Institute, Montreal, Quebec, Canada
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  • Carolyn J. Ewels
    Affiliations
    From the National Institutes of Health, Bethesda, Maryland USA

    From the University of Pittsburgh, Pittsburgh, Pennsylvania USA

    From the Montreal Heart Institute, Montreal, Quebec, Canada
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  • Katherine M. Detre
    Affiliations
    From the National Institutes of Health, Bethesda, Maryland USA

    From the University of Pittsburgh, Pittsburgh, Pennsylvania USA

    From the Montreal Heart Institute, Montreal, Quebec, Canada
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  • Kenneth M. Kent
    Affiliations
    From the National Institutes of Health, Bethesda, Maryland USA

    From the University of Pittsburgh, Pittsburgh, Pennsylvania USA

    From the Montreal Heart Institute, Montreal, Quebec, Canada
    Search for articles by this author
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      Abstract

      Exercise testing after successful PTCA showed improved cardiac functional status on examination of electrocardiographic and symptomatic responses, myocardial perfusion and global and regional left ventricular function. Sixty-six patients were studied before and after persistently successful PTCA. Follow-up studies an average of 8 months after the successful procedure showed an incidence of abnormal testing of only 7% using both electrocardiographic and subjective symptomatic criteria during treadmill studies and no abnormal studies with thallium scintigraphy. Radionuclide cineangiography demonstrated similar left ventricular ejection fractions at rest before and after PTCA, but an improvement of 9 ± 10% (p < 0.001) in the exercise ejection fraction at follow-up. However, 52% of patients with paired data still had an abnormal radionuclide cineangiographic study after successful PTCA, raising the question of the presence of subclinical ischemia or a false-positive result.
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