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Abstract
The occurrence and magnitude of the incisura of the central aortic pressure were shown
in 66 patients to depend on the functional state of the aortic valve. In normal subjects
and children with congenital aortic stenosis (with thin flexible leaflets), the incisura
ranged between 6 and 14 mm Hg. With aortic regurgitation, the incisura diminished
as the severity of regurgitation increased. With calcific aortic stenosis, the incisura
was smaller or absent. These observations imply a valve mechanism productive of the
incisura. In vitro studies of human aortic valves confirmed these observations. Additional
in vitro studies with high speed cinematography (2,000 frames/sec) of a stented normal
porcine valve also showed that early diastolic stretch and recoil of the leaflets
occurs. These results indicate that in the presence of a normal or diseased aortic
valve the aortic incisura is produced primarily by valve distension or recoil, respectively.
Distension and rebound of the aortic walls do not appear to contribute significantly
in the presence of a normal or a diseased valve. Because acquired aortic valve disease
affects the magnitude of the central aortic incisura, inspection of the incisura may
be of ancillary value in evaluating the pathologic state of the aortic valve.
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References
- The genesis and interpretation of cardiovascular pressure pulses.Heart Center Bull St Francis Hosp. 1959; 16: 1-13
- Examination of the arteries.in: Hurst JW Logue RB The Heart, Arteries and Veins. McGraw-Hill, New York1966: 66
- Direct detection and timing of aortic valve closure.Circ Res. 1964; 14: 387-391
- Physiology and Biophysics of the Circulation.in: second edition. Year Book Medical Publishers, Chicago1972: 160-166
- Aortography.in: Grossman W Cardiac Catheterization and Angiography. Lea & Febiger, Philadelphia1974: 150-156
- Dimensions and geometric relationships of the human aortic valve as a function of pressure.Circ Res. 1974; 35: 871-882
- Investigation of the theory and mechanism of the second heart sound.Circ Res. 1976; 39: 874-882
- Effects of structural configuration of prosthetic aortic valves upon coronary blood flow.Br J Surg. 1977; 64: 561-566
- Relation between pressure and diameter in the ascending aorta of man.Circ Res. 1962; 10: 778-781
- Cardiovascular Dynamics.in: third edition. WB Saunders, Philadelphia1970: 301-307
- Relationship of heart sounds to acceleration of blood flow.Circ Res. 1966; 18: 303-315
Article Info
Publication History
Accepted:
June 29,
1977
Received in revised form:
June 27,
1977
Received:
March 11,
1977
Footnotes
☆This study was supported by Project R38820 from funds supplied by the Henry Ford Hospital via a grant from the Ford Foundation, New York, New York.
Identification
Copyright
© 1978 Published by Elsevier Inc.
