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Valve origin of the aortic incisura

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      Abstract

      The occurrence and magnitude of the incisura of the central aortic pressure were shown in 66 patients to depend on the functional state of the aortic valve. In normal subjects and children with congenital aortic stenosis (with thin flexible leaflets), the incisura ranged between 6 and 14 mm Hg. With aortic regurgitation, the incisura diminished as the severity of regurgitation increased. With calcific aortic stenosis, the incisura was smaller or absent. These observations imply a valve mechanism productive of the incisura. In vitro studies of human aortic valves confirmed these observations. Additional in vitro studies with high speed cinematography (2,000 frames/sec) of a stented normal porcine valve also showed that early diastolic stretch and recoil of the leaflets occurs. These results indicate that in the presence of a normal or diseased aortic valve the aortic incisura is produced primarily by valve distension or recoil, respectively. Distension and rebound of the aortic walls do not appear to contribute significantly in the presence of a normal or a diseased valve. Because acquired aortic valve disease affects the magnitude of the central aortic incisura, inspection of the incisura may be of ancillary value in evaluating the pathologic state of the aortic valve.
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      References

        • Opdyke DF
        The genesis and interpretation of cardiovascular pressure pulses.
        Heart Center Bull St Francis Hosp. 1959; 16: 1-13
        • Hurst JW
        • Scnlant RC
        Examination of the arteries.
        in: Hurst JW Logue RB The Heart, Arteries and Veins. McGraw-Hill, New York1966: 66
        • MacCanon DM
        • Arevalo F
        • Meyer EC
        Direct detection and timing of aortic valve closure.
        Circ Res. 1964; 14: 387-391
        • Burton AC
        Physiology and Biophysics of the Circulation.
        in: second edition. Year Book Medical Publishers, Chicago1972: 160-166
        • Delany DJ
        Aortography.
        in: Grossman W Cardiac Catheterization and Angiography. Lea & Febiger, Philadelphia1974: 150-156
        • Swanson WM
        • Clark RE
        Dimensions and geometric relationships of the human aortic valve as a function of pressure.
        Circ Res. 1974; 35: 871-882
        • Sabbah HN
        • Stein PD
        Investigation of the theory and mechanism of the second heart sound.
        Circ Res. 1976; 39: 874-882
        • Sabbah HN
        • Blick EF
        • Stein PD
        Effects of structural configuration of prosthetic aortic valves upon coronary blood flow.
        Br J Surg. 1977; 64: 561-566
        • Greenfield JC
        • Patel DJ
        Relation between pressure and diameter in the ascending aorta of man.
        Circ Res. 1962; 10: 778-781
        • Rushmer RF
        Cardiovascular Dynamics.
        in: third edition. WB Saunders, Philadelphia1970: 301-307
        • Piemme TE
        • Barnett OG
        • Dexter L
        Relationship of heart sounds to acceleration of blood flow.
        Circ Res. 1966; 18: 303-315