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Abstract
An experimental model of a prolapsing left atrial tumor mass has been utilized In
dogs to study the hemodynamic events of the cardiac cycle and the cineangiographic
and echocardiographic manifestations of this condition. The characteristic ventricular
notch has been correlated with the timing of the expulsion of the simulated tumor
mass from the left ventricle to the left atrium. The early notch seen with small simulated
tumors delays aortic ejection by 0.02 to 0.03 second and results in abbreviated aortic
ejection time and minimal distortion of the E-F slope of anterior mitral leaflet motion
in the echocardiogram. Larger masses lead to late ventricular notching, transiently
interrupt aortic flow and may displace the anterior mitral leaflet until It impinges
on the interventricular septum in mid-diastole and at the onset of systole. A transient
systolic Increment of coronary flow is observed after expulsion of the tumor from
the left ventricle into the left atrium. There is an echo-free interval immediately
after opening of the mitral valve, indicating that tumor motion lags perceptibly behind
the initial blood flow through the mitral orifice. The sudden expulsion of the mass
from the ventricle to the atrium early in systole represents an in vivo example of
the quick release phenomenon.
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References
- Diagnosis of left atrial myxoma.Lancet. 1963; 1: 464-468
- Calcified left atrial myxoma simulating mitral insufficiency. Hemodynamic and phonocardiographic effects of tumor movement.Circulation. 1967; 36: 417-421
- Myxoma of the left atrium. Hemodynamic and phonocardiographic consequences of sudden tumor movement.Circulation. 1967; 36: 408-416
- Left atrial myxoma. Phonocardiographic clues to diagnosis.Am J Cardiol. 1969; 23: 588-591
- Unusual hemodynamic findings of diagnostic value in a case of left atrial myxoma.Am J Cardiol. 1969; 23: 592-596
- Atrial myxoma. II. Phonocardiographic, echocardiographic, hemodynamic, and angiographic features in nine cases.Am Heart J. 1972; 83: 810-824
- Protean clinical manifestations of primary tumors of the heart.Am J Med. 1972; 52: 9-18
- Left atrial myxoma. Hemodynamic and phonocardiographic features.Am J Med. 1972; 52: 525-532
- Left atrial myxoma with bacteremia. Report of a case with a bifid systolic apical impulse.Am J Cardiol. 1970; 25: 353-358
- Left atrial myxoma: evidence of tumor movement by apexcardiogram.Chest. 1971; 60: 280-282
- Left atrial myxoma. Diagnosis with the help of the phonocardiogram and apexcardiogram.Arch Intern Med. 1972; 129: 470-474
- An opening snap recorded in a case of tumor of the left atrium.N Engl J Med. 1957; 257: 178-180
- Clinicopathologic conference. second ed. N Engl J Med. 287. 1972: 555-561
- Echocardiographic diagnosis of left atrial myxoma.in: second ed. Mayo Clin Proc. 61. 1968: 620-627
- Diagnosis of atrial tumors by ultrasound.Circulation. 1969; 39: 615-622
- Echocardiographic diagnosis of left atrial myxoma.Chest. 1970; 58: 550-552
- Pressure transients occurring in diastole in the central aorta.Circ Res. 1963; 13: 585-594
- Profile of atrial myxoma.Am J Cardiol. 1968; 21: 367-375
- Seminars in medicine of the Beth Israel Hospital, Boston: mitral regurgitation. second ed. N Engl J Med. 281. 1969: 425-433
- Echocardiographic diagnosis of right atrial myxoma.in: second ed. Mayo Clin Proc. 48. 1973: 284-286
- Fluid mechanics of a model mitral valve.J Physiol. 1970; 207: 72-73
- Newer aspects of echocardiography.Circulation. 1973; 37: 833-842
- The posterior mitral valve echo and the electrocardiographic diagnosis of mitral stenosis.Am J Cardiol. 1972; 29: 628-632
- Time course of the active state in relation to muscle length and movement: a comparative study on skeletal muscle and myocardium.Cardiovasc Res. 1971; 1: 3-10
Article info
Publication history
Accepted:
January 3,
1974
Identification
Copyright
© 1974 Published by Elsevier Inc.
