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Abstract
An experimental model of a prolapsing left atrial tumor mass has been utilized In
dogs to study the hemodynamic events of the cardiac cycle and the cineangiographic
and echocardiographic manifestations of this condition. The characteristic ventricular
notch has been correlated with the timing of the expulsion of the simulated tumor
mass from the left ventricle to the left atrium. The early notch seen with small simulated
tumors delays aortic ejection by 0.02 to 0.03 second and results in abbreviated aortic
ejection time and minimal distortion of the E-F slope of anterior mitral leaflet motion
in the echocardiogram. Larger masses lead to late ventricular notching, transiently
interrupt aortic flow and may displace the anterior mitral leaflet until It impinges
on the interventricular septum in mid-diastole and at the onset of systole. A transient
systolic Increment of coronary flow is observed after expulsion of the tumor from
the left ventricle into the left atrium. There is an echo-free interval immediately
after opening of the mitral valve, indicating that tumor motion lags perceptibly behind
the initial blood flow through the mitral orifice. The sudden expulsion of the mass
from the ventricle to the atrium early in systole represents an in vivo example of
the quick release phenomenon.
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Article info
Publication history
Accepted:
January 3,
1974
Identification
Copyright
© 1974 Published by Elsevier Inc.