Advertisement

Unusual hemodynamic findings of diagnostic value in a case of left atrial myxoma

      This paper is only available as a PDF. To read, Please Download here.

      Abstract

      Unusual laboratory findings in a case of left atrial myxoma are presented. The end-diastolic pressure gradient between the left ventricle and wedge position ranged from 0 to 21 mm. Hg with no relation to heart rate or rhythm, respiration, or wedge position. The y descent was slow rather than the usual rapid y descent associated with mobile atrial myxomas. These findings probably were caused by left atrial inflow obstruction rather than outflow obstruction. Pressure transients owing to sudden acceleration and deceleration of the tumor and surrounding blood, with subsequent oscillations of the heart and great vessels, were recorded in the left ventricle, aorta, external carotid pulse, and external phonocardiogram during the phase of isovolumic contraction and during a period beginning with isovolumic relaxation through rapid ventricular filling. These findings, when present, strongly suggest the presence of a mobile atrial tumor.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to American Journal of Cardiology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Zitnik R.S.
        • Burchell H.B.
        Left atrial myxoma: Phonocardiographic clues to diagnosis.
        Am. J. Cardiol. 1969; 23: 588
        • Fish R.G.
        • Takaro T.
        • Crymes T.
        Left atrial pressure pulses in the presence of myxoma.
        Circulation. 1959; 20: 413
        • Barrillon A.
        • Letac B.
        • Lenegre J.
        Le myxome de l'oreillette gauche.
        Arch. mat. coeur. 1966; 59: 1153
        • Da Costa J.C.
        • Da Fonseca H.M.P.
        Myxome de l'oreillette gauche: Éxérèse; guérison (révision des cas opérés publiés).
        Minerva cardioangiol. (Europea). 1961; 9: 380
        • Ellis Jr., F.H.
        • Mankin H.T.
        • Burchell H.B.
        Myxoma of the atrium: Successful surgical treatment in two cases.
        M. Clin. North America. 1958; 42: 1087
        • Joly F.
        • Gavelle P.
        • Valty J.
        • Carlotti J.
        Contribution à l'étude hémodynamique du myxome de l'oreillette gauche (revue des cas publiés à propos de 2 observations).
        Arch. mal. coeur. 1965; 58: 170
        • Pitt A.
        • Pitt B.
        • Schaefer J.
        • Criley J.M.
        Myxoma of the left atrium: Hemodynamic and phonocardiographic consequences of sudden tumor movement.
        Circulation. 1967; 36: 408
        • Piemme T.E.
        • Dexter L.
        Pressure transients occurring in diastole in the central aorta.
        Circulation Res. 1963; 13: 585
        • Kaufmann G.
        • Rutishauser W.
        • Hegglin R.
        Heart sounds in atrial tumors.
        Am. J. Cardiol. 1961; 8: 350