Advertisement

Left ventricular volume and mass and their significance in heart disease

  • Harold T. Dodge
    Correspondence
    Address for reprints: Harold T. Dodge, M.D., University of Alabama Medical Center, 1919 Seventh Ave. South, Birmingham, Ala. 35233.
    Affiliations
    From the Department of Medicine, Division of Cardiology, University of Alabama Medical Center, and the Veterans Administration Hospital, Birmingham, Ala., USA
    Search for articles by this author
  • William A. Baxley
    Affiliations
    From the Department of Medicine, Division of Cardiology, University of Alabama Medical Center, and the Veterans Administration Hospital, Birmingham, Ala., USA
    Search for articles by this author
      This paper is only available as a PDF. To read, Please Download here.

      Abstract

      Methods are now available for determining left ventricular chamber dimensions, volume, volume curves, wall thickness and mass. These observations, when taken together with left ventricular pressure, can be used to characterize the left ventricle as a pump and determine end-diastolic volume, stroke volume, ejection fraction, rates of ejection and filling, mass, work and work components and power. Methods for deriving these values and their significance in the evaluation of the functional state of the left ventricle in patients with heart disease are discussed.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to American Journal of Cardiology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Dodge H.T.
        • Tannenbaum H.L.
        Left ventricular volume in normal man and alterations with disease (Abstr.).
        Circulation. 1956; 14: 927
        • Chapman C.B.
        • Baker O.
        • Reynolds J.
        • Bonte F.J.
        Use of biplane cinefluorography for measurement of ventricular volume.
        Circulation. 1958; 18: 1105
        • Arvidsson H.
        Angiocardiographic observations in mitral disease, with special reference to the volume variations in the left atrium.
        Acta radiol. 1958;
        • Dodge H.T.
        • Sandler H.
        • Ballew D.W.
        • Lord J.D.
        The use of biplane angiocardiography for the measurement of left ventricular volume in man.
        Am. Heart J. 1960; 60: 762
        • Bunnell I.L.
        • Ikkos D.
        • Rudhe U.G.
        • Swan H.J.C.
        Left heart volumes in coarctation of the aorta.
        Am. Heart J. 1961; 61: 165
        • Arvidsson H.
        Angiocardiographic determination of left ventricular volume.
        Acta radiol. 1961; 56: 321
        • Dodge H.T.
        • Sandler H.
        • Baxley W.A.
        • Hawley R.R.
        Usefulness and limitations of radiographic methods for determining left ventricular volume.
        Am. J. Cardiol. 1966; 18: 10
        • Davila J.C.
        • Sanmarco M.E.
        An analysis of the fit of mathematical models applicable to the measurement of left ventricular volume.
        Am. J. Cardiol. 1966; 18: 31
        • Rackley C.E.
        • Behar V.S.
        • Whalen R.E.
        • McIntosh H.D.
        Biplane cineangiographic determinations of left ventricular function: Pressure-volume relationships.
        Am. Heart J. 1967; 74: 766
        • Gribbe P.
        Comparison of the angiocardiographic and direct Fick methods in determining cardiac output.
        Cardiologia. 1960; 36: 20
        • Dodge H.T.
        • Hay R.E.
        • Sandler H.
        An angiocardiographic method for directly determining left ventricular stroke volume in man.
        Circulation Res. 1962; 11: 739
        • Carleton R.A.
        • Bowyer A.F.
        • Graettinger J.D.
        Overestimation of left ventricular volume by the indicator dilution technique.
        Circulation Res. 1966; 18: 248
        • Miller G.A.H.
        • Swan H.J.C.
        Effect of chronic pressure and volume overload on left heart volumes in subjects with congenital heart disease.
        Circulation. 1964; 30: 205
        • Gribbe P.
        • Hirvonen L.
        • Lind J.
        • Wegelius C.
        Cineangiocardiographic recordings of the cyclic changes in volume of the left ventricle.
        Cardiologia. 1959; 34: 348
        • Greene D.G.
        • Carlisle R.
        • Grant C.
        • Bunnell I.L.
        Estimation of left ventricular volume by one-plane cineangiography.
        Circulation. 1967; 35: 61
        • Sandler H.
        • Dodge H.T.
        The use of single plane angiocardiograms for the calculation of left ventricular volume in man.
        Am. Heart J. 1968; 75: 325
        • Rackley C.E.
        • Hood W.P.
        • Cleveland L.
        • Stacy R.W.
        Derivation of cardiac mechanical parameters from serial biplane angiocardiograms.
        J. Appl. Physiol. 1968; 24: 254
        • Kennedy J.W.
        • Baxley W.A.
        • Figley M.D.
        • Dodge H.T.
        • Blackmon J.R.
        Quantitative angiocardiography. The normal left ventricle in man.
        Circulation. 1966; 34: 272
        • Jones J.W.L.
        Left ventricular volumes in valvular heart disease.
        Circulation. 1964; 29: 887
        • Miller G.A.H.
        • Kirklin J.W.
        • Swan H.J.C.
        Myocardial function and left ventricular volumes in acquired valvular insufficiency.
        Circulation. 1965; 31: 374
        • Bunnell I.L.
        • Grant C.
        • Greene D.G.
        Left ventricular function derived from the pressure-volume diagram.
        Am. J. Med. 1965; 39: 881
        • Dodge H.T.
        • Baxley W.A.
        Hemodynamic aspects of heart failure.
        Am. J. Cardiol. 1968; 22: 24
        • Chapman C.B.
        • Baker O.
        • Mitchell J.H.
        Left ventricular function at rest and during exercise.
        J. Clin. Invest. 1959; 38: 1202
        • Dodge H.T.
        • Sandler H.
        • Hay R.E.
        Left ventricular pressure-volume loops in man with valvular heart disease.
        Circulation. 1961; 24: 920
        • Rackley C.E.
        • Dodge H.T.
        • Coble Y.D.
        • Hay R.E.
        A method for determining left ventricular mass in man.
        Circulation. 1964; 29: 666
        • Kennedy J.W.
        • Reichenbach D.D.
        • Baxley W.A.
        • Dodge H.T.
        Left ventricular mass. A comparison of angiocardiographic measurments with autopsy weight.
        Am. J. Cardiol. 1967; 19: 221
        • Baxley W.A.
        • Dodge H.T.
        • Sandler H.
        A quantitative angiocardiographic study of left ventricular hypertrophy and the electrocardiogram.
        Circulation. 1968; 37: 509
        • Grant C.
        • Greene D.G.
        • Bunnell I.L.
        Left ventricular enlargement and hypertrophy.
        Am. J. Med. 1965; 39: 895
        • Stead E.A.
        • Warren J.V.
        • Brannon E.S.
        Cardiac output in congestive heart failure.
        Am. Heart J. 1948; 35: 529
        • Braunwald E.
        • Ross J.
        • Sonnenblick E.H.
        Mechanisms of contraction of normal and failing heart.
        New England J. Med. 1967; 277: 1012
        • Sarnoff S.J.
        Myocardial contractility as described by ventricular function curves.
        Physiol. Rev. 1955; 35: 107
        • Tsakiris A.G.
        • Vandenberg R.A.
        • Banchero N.
        • Sturm R.E.
        • Wood E.H.
        Variations in left ventricular end-diastolic pressure, volume, and ejection fraction with changes in outflow resistance in anesthetized intact dogs.
        Circulation Res. 1968; 23: 213
        • Sarnoff S.J.
        • Mitchell J.H.
        Control of function of the heart.
        in: ed. 3. Handbook of Physiology, Sect. 2, Circulation. Vol. I. American Physiological Society, Washington, D. C1962: 489-532 (Chap. 15)