| Coronary Artery Disease |
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Effect of Blood Glucose Concentrations on Admission in Non-Diabetic Versus Diabetic Patients With First Acute Myocardial Infarction on Short- and Long-Term Mortality (from the MONICA/KORA Augsburg Myocardial Infarction Registry)
The aim of this study was to investigate the association between increased admission glucose in nondiabetic (ND) patients and in patients with type 2 diabetes mellitus (T2DM) with first acute myocardi...
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Judith A. Beck,
Christa Meisinger,
Margit Heier,
Bernhard Kuch,
Allmut Hörmann,
Claudia Greschik,
Wolfgang Koenig
et al.
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Full-length article
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pages 1607-1612
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Impact of Prior Statin Therapy on Arrhythmic Events in Patients With Acute Coronary Syndromes (from the Global Registry of Acute Coronary Events [GRACE])
Animal models of myocardial ischemia have demonstrated reduction in arrhythmias using statins. It was hypothesized that previous statin therapy before hospitalization might be associated with reductio...
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Ameeth Vedre,
Hitinder S. Gurm,
James B. Froehlich,
Eva Kline-Rogers,
Gilles Montalescot,
Joel M. Gore,
David Brieger,
Ann L. Quill,
Kim A. Eagle,
GRACE Investigators
et al.
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Full-length article
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pages 1613-1617
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Effect of Atorvastatin on Platelet Thromboxane A2 Synthesis in Aspirin-Treated Patients With Acute Myocardial Infarction
Inhibition of platelet thromboxane A2 (TXA2) by aspirin is critical in patients with acute myocardial infarction (AMI), but some patients have persistent platelet TXA2 production within 48 hours of th...
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M. Teresa Santos,
M. Paz Fuset,
Miguel Ruano,
Antonio Moscardó,
Juana Valles
et al.
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Full-length article
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pages 1618-1623
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Usefulness of the Duke Sudden Cardiac Death Risk Score for Predicting Sudden Cardiac Death in Patients With Angiographic (>75% Narrowing) Coronary Artery Disease
The currently available sudden cardiac death (SCD) risk prediction tools fail to identify most at-risk patients and cannot delineate a specific patient's SCD risk. We sought to develop a tool to impro...
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Brett D. Atwater,
Vivian P. Thompson,
Richard N. Vest,
Linda K. Shaw,
Walter R. Mazzei,
Sana M. Al-Khatib,
Patrick M. Hranitzky,
Tristram D. Bahnson,
Eric J. Velazquez,
Robert M. Califf,
Kerry L. Lee,
Matthew T. Roe
et al.
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Full-length article
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pages 1624-1630
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Usefulness of Fragmented QRS on a 12-Lead Electrocardiogram in Acute Coronary Syndrome for Predicting Mortality
Electrocardiographic signs of a non–ST elevation myocardial infarction (NSTEMI) are nonspecific, and therefore the diagnosis of NSTEMI during acute coronary syndromes (ACS) depends mainly on cardiac b...
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Mithilesh K. Das,
Mark A. Michael,
Hussam Suradi,
Jonathan Peng,
Anjan Sinha,
Changyu Shen,
Jo Mahenthiran,
Richard J. Kovacs
et al.
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Full-length article
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pages 1631-1637
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Relation of Nausea and Vomiting in Acute Myocardial Infarction to Location of the Infarct
To determine whether the incidence of nausea and vomiting in patients with acute myocardial infarction (AMI) varies with infarct location, we studied 180 patients who had been admitted to our hospital...
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Eileen E. Fuller,
Rahel Alemu,
John F. Harper,
Mark Feldman
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Full-length article
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pages 1638-1640
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Prevalence and Significance of Accelerated Idioventricular Rhythm in Patients With ST-Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention
Accelerated idioventricular rhythm (AIVR) has been considered a marker of successful reperfusion in fibrinolytic-treated patients. Evidence is limited regarding its significance in patients with ST-el...
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Christian Juhl Terkelsen,
Jacob Thorsted Sørensen,
Anne Kjer Kaltoft,
Søren Steen Nielsen,
Leif Thuesen,
Hans-Erik Bøtker,
Jens Flensted Lassen
et al.
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Full-length article
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pages 1641-1646
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Optimal Medical Therapy With or Without Percutaneous Coronary Intervention for Patients With Stable Coronary Artery Disease and Chronic Kidney Disease
Chronic kidney disease (CKD) is a risk factor for poor outcomes in patients with coronary artery disease (CAD), but it is unknown whether CKD influences the efficacy of alternative CAD treatment strat...
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Steven P. Sedlis,
Claudine T. Jurkovitz,
Pamela M. Hartigan,
David S. Goldfarb,
Jeffrey D. Lorin,
Marcin Dada,
David J. Maron,
John A. Spertus,
G.B. John Mancini,
Koon K. Teo,
Robert A. O'Rourke,
William E. Boden,
William S. Weintraub,
COURAGE Study Investigators
et al.
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Full-length article
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pages 1647-1653
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Effect of Drug-Eluting Stents on Frequency of Repeat Revascularization in Patients With Unstable Angina Pectoris or Non-ST-Elevation Myocardial Infarction
Drug-eluting stents (DES) have been shown to markedly reduce the need for repeat revascularization compared to bare-metal stents in patients with stable coronary artery disease. The benefit of DES in ...
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Yanlin Li,
Rebecca Torguson,
Asmir I. Syed,
Itsik Ben-Dor,
Sara D. Collins,
Gabriel Maluenda,
Mickey Scheinowitz,
Kimberly Kaneshige,
Zhenyi Xue,
Gilles Lemesle,
Lowell F. Satler,
William O. Suddath,
Kenneth M. Kent,
Joseph Lindsay,
Augusto D. Pichard,
Ron Waksman
et al.
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Full-length article
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pages 1654-1659
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Histopathology of Clinical Coronary Restenosis in Drug-Eluting Versus Bare Metal Stents
To characterize in-stent restenosis after the implantation of sirolimus-eluting stents (SES), paclitaxel-eluting stents (PES), tacrolimus-eluting stents (TES), and zotarolimus-eluting stents (ZES), 25...
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Alaide Chieffo,
Chiara Foglieni,
Rota Laura Nodari,
Carlo Briguori,
Giuseppe Sangiorgi,
Azeem Latib,
Matteo Montorfano,
Flavio Airoldi,
Iassen Michev,
Mauro Carlino,
Antonio Colombo,
Attilio Maseri
et al.
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Full-length article
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pages 1660-1667
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Reasonable Duration of Clopidogrel Use After Drug-Eluting Stent Implantation in Korean Patients
Current guidelines recommend that clopidogrel be given to patients for 12 months after drug-eluting stent (DES) implantation. However, the evidence is insufficient to support the benefit of long-term ...
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Dong-Ho Shin,
In-Ho Chae,
Tae-Jin Youn,
Sung-Il Cho,
Dong-A. Kwon,
Jung-Won Suh,
Hyuk-Jae Chang,
Young-Seok Cho,
Woo-Young Chung,
Young-Jin Choi,
Hyeon-Cheol Gwon,
Kyoo-Rok Han,
Dong-Ju Choi
et al.
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Full-length article
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pages 1668-1673
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Incidence, Risk Factors, Management and Outcomes of Coronary Artery Perforation During Percutaneous Coronary Intervention
Coronary artery perforation (CP) is a rare, sometimes lethal complication of percutaneous coronary intervention. There are limited controlled contemporary data regarding its predictors, incidence, and...
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Avi Shimony,
Doron Zahger,
Michael Van Straten,
Aryeh Shalev,
Harel Gilutz,
Reuben Ilia,
Carlos Cafri
et al.
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Full-length article
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pages 1674-1677
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Malignant Ventricular Arrhythmias in Patients With Acute Right Ventricular Infarction Undergoing Mechanical Reperfusion
Patients with acute right ventricular (RV) infarctions are prone to ventricular arrhythmias, but little is known regarding the temporal patterns of these arrhythmias, their impact on outcomes, or thei...
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Jason M. Ricci,
Srinivas R. Dukkipati,
Mark C. Pica,
David E. Haines,
James A. Goldstein
et al.
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Full-length article
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pages 1678-1683
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Effectiveness and Safety of Total Endoscopic Left Internal Mammary Artery Bypass Graft to the Left Anterior Descending Artery
Totally endoscopic coronary artery bypass grafting (CABG) has become a feasible option using robotic technology and remote access perfusion techniques. The aim of this study was to determine the progr...
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Johannes Bonatti,
Thomas Schachner,
Nikolaos Bonaros,
Armin Oehlinger,
Dominik Wiedemann,
Elisabeth Ruetzler,
Felix Weidinger,
Christian Kolbitsch,
Gudrun Feuchtner,
David Zimrin,
Guy Friedrich,
Otmar Pachinger,
Guenther Laufer
et al.
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Full-length article
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pages 1684-1688
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| Preventive Cardiology |
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Article Title |
Author(s) |
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Frequency of Obtaining National Cholesterol Education Program Adult Treatment Panel III Goals for All Major Serum Lipoproteins After Initiation of Lipid Altering Therapy†
Statin treatment targeting low-density lipoprotein (LDL) cholesterol is widely used for cardiovascular risk reduction, but many statin users still face greatly elevated risks. Some experts advocate ad...
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Gregory A. Nichols,
Baishali M. Ambegaonkar,
Vasilisa Sazonov,
Jonathan B. Brown
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Full-length article
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pages 1689-1694
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| Editorial |
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Author(s) |
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Optimal Management of Persistent Mixed Dyslipidemia After Statin Initiation Warrants Combination Therapy
In this issue, Nichols et al describe the results of a longitudinal research study evaluating the impact of contemporary lipid management on the attainment of lipid goals and treatment targets. In a n...
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William E. Boden,
Mark E. McGovern
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Editorial
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pages 1695-1696
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Keeping Our Eyes on the Prize: Low Density Lipoprotein Cholesterol
National guidelines for the treatment of dyslipidemia remain squarely focused on low-density lipoprotein (LDL) cholesterol. For example, in the most recent iteration of the National Cholesterol Educat...
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James A. de Lemos,
Amit Khera
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Editorial
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pages 1697-1698
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| Arrhythmias and Conduction Disturbances |
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Body Mass Index and Risk of Left Atrial Thrombus in Patients With Atrial Fibrillation
This study sought to assess the impact of body mass index (BMI) on the risk of left atrial (LA)/left atrial appendage (LAA) thrombus in patients with atrial fibrillation (AF) before catheter ablation....
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Ri-Bo Tang,
Xiao-Hui Liu,
Jérôme Kalifa,
Zhi-An Li,
Jian-Zeng Dong,
Ya Yang,
Xing-Peng Liu,
De-Yong Long,
Rong-Hui Yu,
Chang-Sheng Ma
et al.
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Full-length article
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pages 1699-1703
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Relation of Urotensin II Levels to Lone Atrial Fibrillation
Human urotensin II (U-II) is an 11–amnio acid peptide that plays an important role in hypertension and coronary artery disease. However, because there is no information on the role of U-II in the deve...
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Lu Zhang,
Ru Ding,
Yi Zhen,
Zong-Gui Wu
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Full-length article
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pages 1704-1707
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| Heart Failure |
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Author(s) |
Type |
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Meta-Analysis of Randomized Controlled Trials of Statins Versus Placebo in Patients With Heart Failure
Although statins have been shown to improve outcomes in retrospective analyses of patients with heart failure (HF), recent randomized placebo-controlled trials have shown mixed results. The goal of th...
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Michael J. Lipinski,
Clay A. Cauthen,
Giuseppe G.L. Biondi-Zoccai,
Antonio Abbate,
Bojan Vrtovec,
Bobby V. Khan,
George W. Vetrovec
et al.
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Full-length article
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pages 1708-1716
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| Valvular Heart Disease |
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Comparison of the Results of Aortic Valve Replacement With or Without Concomitant Coronary Artery Bypass Grafting in Patients With Left Ventricular Ejection Fraction ≤30% Versus Patients With Ejection Fraction >30%
The present study was designed to test the hypothesis that low-ejection fraction (EF), low-gradient aortic stenosis (AS) is a predictor of major morbidity after aortic valve replacement (AVR). We retr...
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Joanna Chikwe,
Lori B. Croft,
Andrew B. Goldstone,
Javier G. Castillo,
Parwis B. Rahmanian,
David H. Adams,
Farzan Filsoufi
et al.
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Full-length article
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pages 1717-1721
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| Cardiomyopathy |
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Relation of 12-Lead Electrocardiogram Patterns to Implanted Defibrillator-Terminated Ventricular Tachyarrhythmias in Hypertrophic Cardiomyopathy
Electrocardiographic (ECG) abnormalities are common in hypertrophic cardiomyopathy (HC) and have been associated with the distribution of left ventricular hypertrophy and myocardial fibrosis. Such abn...
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Mark V. Sherrid,
Delia Cotiga,
David Hart,
Frederick Ehlert,
Tammy S. Haas,
Win-Kuang Shen,
Mark S. Link,
N.A. Mark Estes,
Andrew E. Epstein,
Christopher Semsarian,
James P. Daubert,
Stephen L. Winters,
Michael C. Giudici,
Barry J. Maron
et al.
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Full-length article
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pages 1722-1726
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Prognostic Implications of the Doppler Restrictive Filling Pattern in Hypertrophic Cardiomyopathy
The Doppler echocardiographic pattern of restrictive left ventricular (LV) filling has proved to be an important predictor of clinical course and prognosis in dilated cardiomyopathy. However, the rela...
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Elena Biagini,
Paolo Spirito,
Guido Rocchi,
Marinella Ferlito,
Stefania Rosmini,
Francesco Lai,
Massimiliano Lorenzini,
Francesca Terzi,
Letizia Bacchi-Reggiani,
Giuseppe Boriani,
Angelo Branzi,
Luca Boni,
Claudio Rapezzi
et al.
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Full-length article
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pages 1727-1731
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| Congenital Heart Disease |
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Usefulness of Early Diastolic Mitral Annular Velocity to Predict Plasma Levels of Brain Natriuretic Peptide and Transient Heart Failure Development After Device Closure of Atrial Septal Defect
Device closure of atrial septal defect (ASD) is sometimes followed by elevation of plasma brain natriuretic peptide (BNP), a marker of heart failure, and progression to heart failure. This study teste...
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Satoshi Masutani,
Mio Taketazu,
Chihiro Mihara,
Yuko Mimura,
Hirotaka Ishido,
Tamotsu Matsunaga,
Toshiki Kobayashi,
Hideaki Senzaki
et al.
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Full-length article
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pages 1732-1736
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Atrial Remodeling After the Fontan Operation
The hemodynamics after Fontan surgery are notable for hypertension and dilation of the right atrium (RA). The effect of this stress on atrial cytoarchitecture has not been systematically studied and m...
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Cordula M. Wolf,
Stephen P. Seslar,
Karen den Boer,
Amy L. Juraszek,
Francis X. McGowan,
Douglas B. Cowan,
Pedro Del Nido,
John K. Triedman,
Charles I. Berul,
Edward P. Walsh
et al.
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Full-length article
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pages 1737-1742
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| Miscellaneous |
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Comparison of Factors Associated With Coronary Artery Dilation Only Versus Coronary Artery Aneurysms in Patients With Kawasaki Disease
We sought to determine whether differences exist in the factors associated with transient coronary artery (CA) dilation only compared to CA aneurysms after Kawasaki disease (KD). We reviewed all patie...
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Tarun Sabharwal,
Cedric Manlhiot,
Susanne M. Benseler,
Pascal N. Tyrrell,
Nita Chahal,
Rae S.M. Yeung,
Brian W. McCrindle
et al.
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Full-length article
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pages 1743-1747
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Pleiotropy of C-Reactive Protein Gene Polymorphisms With C-Reactive Protein Levels and Heart Rate Variability in Healthy Male Twins
Reduced heart rate variability (HRV) and increased C-reactive protein (CRP) levels are both predictors of coronary artery disease and correlate with each other. We examined whether these 2 phenotypes ...
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Shaoyong Su,
Rachel Lampert,
Jinying Zhao,
James Douglas Bremner,
Andrew Miller,
Harold Snieder,
Forrester Lee,
Durreshahwar Khan,
Jack Goldberg,
Viola Vaccarino
et al.
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Full-length article
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pages 1748-1754
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| Methods |
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Author(s) |
Type |
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Quantitative Evaluation of Regional Left Ventricular Function Using Three-Dimensional Speckle Tracking Echocardiography in Patients With and Without Heart Disease
Although 2-dimensional (2D) speckle tracking echocardiography has been shown to be useful in the assessment of regional left ventricular function, it is limited by the assumption that speckles can be ...
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Francesco Maffessanti,
Hans-Joachim Nesser,
Lynn Weinert,
Regina Steringer-Mascherbauer,
Johannes Niel,
Willem Gorissen,
Lissa Sugeng,
Roberto M. Lang,
Victor Mor-Avi
et al.
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Full-length article
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pages 1755-1762
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| Readers' Comments |
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Contrast-Induced Nephropathy Morbidity and Mortality Following Percutaneous Coronary Intervention
The recent publication by Jabara et al from the Oxilan Registry reported rates of contrast-induced nephropathy (CIN) in a convenience sample of patients who underwent percutaneous coronary interventio...
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Jeremiah R. Brown,
Richard J. Solomon
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Correspondence
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page 1763
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Author Index
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Index
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pages e1-e7
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Subject Index
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Index
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pages e8-e25
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| Frontmatter |
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Author(s) |
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Editorial Board
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Editorial board
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page A4
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Contents
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Contents list
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page A7
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