| Coronary Artery Disease |
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Effects of Combination Lipid Therapy on Coronary Stenosis Progression and Clinical Cardiovascular Events in Coronary Disease Patients With Metabolic Syndrome: A Combined Analysis of the Familial Atherosclerosis Treatment Study (FATS), the HDL-Atherosclerosis Treatment Study (HATS), and the Armed Forces Regression Study (AFREGS)
We examined the impact of metabolic syndrome (MS) on coronary stenosis progression and major cardiovascular (CV) events and investigated the mitigating effects of low-density lipoprotein (LDL) cholest...
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Xue-Qiao Zhao,
Richard A. Krasuski,
Jefferson Baer,
Edwin J. Whitney,
Blazej Neradilek,
Alan Chait,
Santica Marcovina,
John J. Albers,
B. Greg Brown
et al.
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Full-length article
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pages 1457-1464
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Usefulness of Pregnancy-Associated Plasma Protein A in Patients With Acute Coronary Syndrome
To investigate whether pregnancy-associated plasma protein-A (PAPP-A) is a prognostic marker in patients admitted with high-risk acute coronary syndrome. In patients admitted with high-risk non–ST-seg...
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Kasper K. Iversen,
Morten Dalsgaard,
Ane S. Teisner,
Mikkel Schoos,
Borge Teisner,
Henrik Nielsen,
Peter Clemmensen,
Peer Grande
et al.
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Full-length article
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pages 1465-1471
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Relation of Cardiac Troponin I Measurements at 24 and 48 Hours to Magnetic Resonance–Determined Infarct Size in Patients With ST-Elevation Myocardial Infarction
16 October 2009
Levels of circulating cardiac troponin I (cTnI) or T are correlated to extent of myocardial destruction after an acute myocardial infarction. Few studies analyzing this relation have employed a second...
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Jonas Hallén,
Peter Buser,
Jürg Schwitter,
Peter Petzelbauer,
Bernard Geudelin,
Morten W. Fagerland,
Allan S. Jaffe,
Dan Atar
et al.
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Full-length article
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pages 1472-1477
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Usefulness of Soluble Fms-like Tyrosine Kinase-1 as a Biomarker of Acute Severe Heart Failure in Patients With Acute Myocardial Infarction
Placental growth factor and vascular endothelial growth factor increase angiogenesis and promote healing after acute myocardial infarction (MI), but the significance of soluble Fms-like tyrosine kinas...
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Kenji Onoue,
Shiro Uemura,
Yukiji Takeda,
Satoshi Somekawa,
Hajime Iwama,
Taku Nishida,
Yoshinobu Morikawa,
Hitoshi Nakagawa,
Takeshi Tsutsumi,
Ji Hee Sung,
Yasuhiro Takemoto,
Tsunenari Soeda,
Satoshi Okayama,
Kenichi Ishigami,
Hiroyuki Kawata,
Manabu Horii,
Tamio Nakajima,
Yoshihiko Saito
et al.
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Full-length article
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pages 1478-1483
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Left Ventricular Mass and Volume With Telmisartan, Ramipril, or Combination in Patients With Previous Atherosclerotic Events or With Diabetes Mellitus (from the ONgoing Telmisartan Alone and in Combination With Ramipril Global Endpoint Trial [ONTARGET])
16 October 2009
The ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial (ONTARGET) showed that the angiotensin receptor blocker telmisartan 80 mg was not inferior to the angiotensin-conve...
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Brett R. Cowan,
Alistair A. Young,
Craig Anderson,
Robert N. Doughty,
Rungroj Krittayaphong,
Eva Lonn,
Thomas H. Marwick,
Chris M. Reid,
John E. Sanderson,
Roland E. Schmieder,
Koon Teo,
Angela K. Wadham,
Stephen G. Worthley,
Cheuk-Man Yu,
Salim Yusuf,
Garry L. Jennings,
ONTARGET Investigators
et al.
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Full-length article
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pages 1484-1489
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Prognostic Significance of QRS Duration in Patients With Suspected Coronary Artery Disease Referred for Noninvasive Evaluation of Myocardial Ischemia
19 October 2009
The purpose of this study was to evaluate the prognostic significance of QRS duration in patients with suspected coronary artery disease (CAD) referred for noninvasive evaluation of myocardial ischemi...
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Arend F.L. Schinkel,
Abdou Elhendy,
Ron T. van Domburg,
Elena Biagini,
Vittoria Rizzello,
Caroline E. Veltman,
Gerrit L. ten Kate,
Eric J. Sijbrands,
K. Martijn Akkerhuis,
Marcel L. Geleijnse,
Folkert J. ten Cate,
Maarten L. Simoons,
Jeroen J. Bax,
Don Poldermans
et al.
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Full-length article
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pages 1490-1493
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Impact of Clinical and Subclinical Peripheral Arterial Disease in Mid-Term Prognosis of Patients With Acute Coronary Syndrome
Observational studies report poor prognosis of patients after acute coronary syndrome (ACS) in the presence of previous peripheral arterial disease (PAD), but data on subclinical PAD are scarce. This ...
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Pedro Morillas,
Juan Quiles,
Alberto Cordero,
Josep Guindo,
Federico Soria,
Pilar Mazón,
Jose Ramón Gonzalez-Juanatey,
Vicente Bertomeu,
Prevalence of Peripheral Arterial Disease in Patients With Acute Coronary Syndrome (PAMISCA) Investigators
et al.
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Full-length article
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pages 1494-1498
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Comparison of the Value of Coronary Calcium Detection to Computed Tomographic Angiography and Exercise Testing in Patients With Chest Pain
The aim of this study was to investigate the value of coronary calcium detection by computed tomography compared to computed tomographic angiography (CTA) and exercise testing to detect obstructive co...
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Koen Nieman,
Tjebbe W. Galema,
Lisan A. Neefjes,
Annick C. Weustink,
Paul Musters,
Adriaan D. Moelker,
Nico R. Mollet,
Randall de Visser,
Eric Boersma,
Pim J. de Feijter
et al.
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Full-length article
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pages 1499-1504
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Is It Possible to Safely Administer Early a Loading Dose of Clopidogrel Before Coronary Angiography to Patients Who Are Candidates for Percutaneous Coronary Intervention?
16 October 2009
Current American College of Cardiology/American Heart Association guidelines recommend loading clopidogrel ≥6 hours before percutaneous coronary intervention. Other American College of Cardiology guid...
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Theresa Poppe,
Bonita Singal,
Mark Cowen,
Avinash Srikanth,
Tauqir Y. Goraya
et al.
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Full-length article
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pages 1505-1510
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Relation of Body Mass Index to High On-Treatment Platelet Reactivity and of Failed Clopidogrel Dose Adjustment According to Platelet Reactivity Monitoring in Patients Undergoing Percutaneous Coronary Intervention
19 October 2009
High on-treatment platelet reactivity (HTPR) after a clopidogrel loading dose predicts the risk of thrombotic events after percutaneous coronary intervention. We have demonstrated that HTPR could be o...
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Nathalie Bonello-Palot,
Sébastien Armero,
Franck Paganelli,
Julien Mancini,
Axel De Labriolle,
Caroline Bonello,
Nicolas Lévy,
Luc Maillard,
Paul Barragan,
Françoise Dignat-George,
Laurence Camoin-Jau,
Laurent Bonello
et al.
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Full-length article
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pages 1511-1515
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| Preventive Cardiology |
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Relation Among Lipoprotein Subfractions and Carotid Atherosclerosis in Alaskan Eskimos (from the GOCADAN Study)
16 October 2009
Studies have been inconsistent regarding whether lipoprotein particle subfraction measures are useful indicators of cardiovascular risk. The present study evaluated the relation between lipoprotein pa...
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Maria Masulli,
Lidia Patti,
Gabriele Riccardi,
Olga Vaccaro,
Giovanni Annuzzi,
Sven O.E. Ebbesson,
Richard R. Fabsitz,
Wm. James Howard,
James D. Otvos,
Mary J. Roman,
Hong Wang,
Neil J. Weissman,
Barbara V. Howard,
Angela A. Rivellese
et al.
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Full-length article
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pages 1516-1521
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Ability of Physical Activity to Predict Cardiovascular Disease Beyond Commonly Evaluated Cardiometabolic Risk Factors
It is well-established that increasing physical activity (PA) is important for the prevention and management of cardiovascular disease (CVD). Although it has been demonstrated that PA predicts CVD ind...
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K. Ashlee McGuire,
Ian Janssen,
Robert Ross
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Full-length article
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pages 1522-1526
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Contribution of Central and General Adiposity to Abnormal Left Ventricular Diastolic Function in a Community Sample With a High Prevalence of Obesity
16 October 2009
The relative independent contribution of excess adiposity, as indexed by measures of central, general, or peripheral adiposity, toward abnormal cardiac diastolic chamber function at a community level ...
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Carlos D. Libhaber,
Gavin R. Norton,
Olebogeng H.I. Majane,
Elena Libhaber,
Mohammed R. Essop,
Richard Brooksbank,
Muzi Maseko,
Angela J. Woodiwiss
et al.
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Full-length article
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pages 1527-1533
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| Arrhythmias and Conduction Disturbances |
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Increasing Prevalence of Atrial Fibrillation and Flutter in the United States
The prevalence data for atrial fibrillation (AF) are dated. The present retrospective study estimated the current and projected prevalence of AF and atrial flutter (AFL) in the United States using a l...
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Gerald V. Naccarelli,
Helen Varker,
Jay Lin,
Kathy L. Schulman
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Full-length article
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pages 1534-1539
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Magnetic Resonance Imaging Versus Computed Tomography for Characterization of Pulmonary Vein Morphology Before Radiofrequency Catheter Ablation of Atrial Fibrillation
15 October 2009
The accurate assessment of pulmonary vein (PV) anatomy is important in planning radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF). The aim of the present study was to perform a head-...
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Ashraf Hamdan,
Kriatselis Charalampos,
Rainer Roettgen,
Ernst Wellnhofer,
Rolf Gebker,
Ingo Paetsch,
Cosima Jahnke,
Bernhard Schnackenburg,
Min Tang,
Hong Gerds-Li,
Eckart Fleck
et al.
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Full-length article
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pages 1540-1546
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Comparison of Antero-Lateral Versus Antero-Posterior Electrode Position for Biphasic External Cardioversion of Atrial Flutter†
External cardioversion is an established and very important tool to terminate symptomatic atrial flutter. The superiority of the biphasic waveform has been demonstrated for atrial flutter, but whether...
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Tim Risius,
Kai Mortensen,
Tjark F. Schwemer,
Muhammet A. Aydin,
Hanno U. Klemm,
Rodolfo Ventura,
Achim Barmeyer,
Boris Hoffmann,
Thomas Rostock,
Thomas Meinertz,
Stephan Willems
et al.
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Full-length article
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pages 1547-1550
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Relation of Kidney Function and Albuminuria With Atrial Fibrillation (from the Heart and Soul Study)
Atrial fibrillation (AF) is common in end-stage renal disease, but the relation between more modest decrements in kidney function or albuminuria with AF is uncertain. Among 956 outpatients with corona...
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David D. McManus,
David C.M. Corteville,
Michael G. Shlipak,
Mary A. Whooley,
Joachim H. Ix
et al.
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Full-length article
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pages 1551-1555
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| Heart Failure |
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Usefulness of Non-Invasive Measurement of Cardiac Output During Sub-Maximal Exercise to Predict Outcome in Patients With Chronic Heart Failure
15 October 2009
Peak oxygen consumption (Vo2) is a powerful prognostic predictor of survival in patients with chronic heart failure (CHF) because it provides an indirect assessment of a patient's ability to increase ...
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Ayumi Goda,
Chim C. Lang,
Paula Williams,
Margaret Jones,
Mary Jane Farr,
Donna M. Mancini
et al.
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Full-length article
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pages 1556-1560
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| Valvular Heart Disease |
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Comparison of Dual-Source Computed Tomography for the Quantification of the Aortic Valve Area in Patients With Aortic Stenosis Versus Transthoracic Echocardiography and Invasive Hemodynamic Assessment
We compared the measurements of the aortic valve area (AVA) using dual-source computed tomography (DSCT) in patients with mid to severe aortic stenosis to measurements using transthoracic echocardiogr...
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Dieter Ropers,
Ulrike Ropers,
Mohammed Marwan,
Titiano Schepis,
Tobias Pflederer,
Martin Wechsel,
Lutz Klinghammer,
Frank A. Flachskampf,
Werner G. Daniel,
Stephan Achenbach
et al.
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Full-length article
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pages 1561-1567
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| Cardiomyopathy |
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Usefulness of Carvedilol to Abolish Myocardial Postsystolic Shortening in Patients With Idiopathic Dilated Cardiomyopathy
16 October 2009
Postsystolic shortening (PSS), a positive myocardial velocity after aortic valve closure as assessed by Doppler tissue imaging, is a common pathologic finding in patients with myocardial disease. Beta...
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Takahide Ito,
Yasunori Kawanishi,
Rie Futai,
Fumio Terasaki,
Yasushi Kitaura
et al.
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Full-length article
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pages 1568-1573
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Frequency of Cardiac Death in Children With Idiopathic Dilated Cardiomyopathy
16 October 2009
The prognosis in children with idiopathic dilated cardiomyopathy (IDC) is guarded, with the 5-year mortality rate ranging from 14% to 50%, owing to sudden cardiac death (SCD) or pump failure. The risk...
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V. Vivian Dimas,
Susan W. Denfield,
Richard A. Friedman,
Bryan C. Cannon,
Jeffrey J. Kim,
E.O.'Brian Smith,
Sarah K. Clunie,
Jack F. Price,
Jeffrey A. Towbin,
William J. Dreyer,
Naomi J. Kertesz
et al.
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Full-length article
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pages 1574-1577
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| Miscellaneous |
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Natural History of Syphilitic Aortitis
18 September 2009
No large studies of cardiovascular syphilis at necropsy have been reported since 1964. We examined at necropsy 90 patients who had characteristic morphologic findings of syphilitic aortitis. None had ...
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William Clifford Roberts,
Jong Mi Ko,
Travis James Vowels
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Full-length article
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pages 1578-1587
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Identifying Cardiovascular Syphilis at Operation
18 September 2009
To describe the morphologic features so the process can be easily identified during surgery, we studied 34 patients with cardiovascular syphilis, 32 of whom underwent excision and replacement of the a...
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William Clifford Roberts,
Rahul Bose,
Jong Mi Ko,
Albert Carl Henry,
Baron Lloyd Hamman
et al.
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Full-length article
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pages 1588-1594
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Full Blown Cardiovascular Syphilis with Aneurysm of the Innominate Artery
18 September 2009
The investigators report the case of a 44-year-old man who presented acutely and was found to have saccular aneurysm of the innominate artery, narrowed or totally occluded aortic arch arteries, and ma...
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William Clifford Roberts,
Forrester Dubus Lensing,
Harry Kourlis,
Jong Mi Ko,
Jonathan Warren Newberry,
Michael John Smerud,
Elizabeth C. Burton,
Robert Frederick Hebeler
et al.
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Short communication
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pages 1595-1600
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Relation of Epicardial Fat Thickness to Right Ventricular Cavity Size in Obese Subjects
19 October 2009
Epicardial fat is the visceral fat depot of the heart and is commonly increased in obese subjects. Obesity is also associated with right ventricular (RV) enlargement. Nevertheless, whether epicardial ...
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Gianluca Iacobellis
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Full-length article
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pages 1601-1602
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| Editorial |
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Another Look at the Results of the JUPITER Trial
16 October 2009
Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) was a placebo-controlled trial undertaken on “apparently healthy” subjects selected primaril...
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C. Tissa Kappagoda,
Ezra A. Amsterdam
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Editorial
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pages 1603-1605
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| Frontmatter |
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Editorial Board
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Editorial board
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page A9
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Contents
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Contents list
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page A11
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