| Coronary Artery Disease |
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Article Title |
Author(s) |
Type |
Pages |
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Impact of Optimal Medical Therapy With or Without Percutaneous Coronary Intervention on Long-Term Cardiovascular End Points in Patients With Stable Coronary Artery Disease (from the COURAGE Trial)
20 April 2009
The main results of the Clinical Outcomes Utilizing Revascularization and Aggressive DruG Evaluation (COURAGE) trial revealed no significant differences in the primary end point of all-cause mortality...
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William E. Boden,
Robert A. O'Rourke,
Koon K. Teo,
David J. Maron,
Pamela M. Hartigan,
Steven P. Sedlis,
Marcin Dada,
Mohammed Labedi,
John A. Spertus,
William J. Kostuk,
Daniel S. Berman,
Leslee J. Shaw,
Bernard R. Chaitman,
G.B. John Mancini,
William S. Weintraub,
COURAGE Trial Investigators
et al.
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Full-length article
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pages 1-4
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Rate of Acute ST-Elevation Myocardial Infarction in the United States from 1988 to 2004 (from the Nationwide Inpatient Sample)
14 May 2009
Advances in the management of atherosclerosis risk factors have been dramatic in the previous 10 years. The goal of this study was to evaluate any decrease in age-adjusted incidence of acute ST-elevat...
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Mohammad Reza Movahed,
Radhakrishnan Ramaraj,
Mehrnoosh Hashemzadeh,
M. Mazen Jamal,
Mehrtash Hashemzadeh
et al.
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Full-length article
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pages 5-8
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Frequency of Elevated Troponin I and Diagnosis of Acute Myocardial Infarction
05 May 2009
This study evaluated the incidence and type of acute myocardial infarction (AMI) in a consecutive population with increased troponin I (TnI). AMI has recently been redefined and subclassified. Inciden...
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Usman Javed,
Waqas Aftab,
John A. Ambrose,
Ralph J. Wessel,
Mouatou Mouanoutoua,
Grace Huang,
Rajat S. Barua,
Michael Weilert,
Fridolin Sy,
Deepak Thatai
et al.
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Full-length article
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pages 9-13
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Safety of Contrast in Stress Echocardiography in Stable Patients and in Patients With Suspected Acute Coronary Syndrome but Negative 12-Hour Troponin
20 April 2009
Limited studies are available demonstrating the safety of contrast agents in patients undergoing stress echocardiography and none in patients with suspected acute coronary syndrome (ACS). Therefore, w...
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Brijesh Anantharam,
Navtej Chahal,
Rajesh Chelliah,
Ihab Ramzy,
Firoz Gani,
Roxy Senior
et al.
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Full-length article
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pages 14-18
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Usefulness of Left Ventricular Dyssynchrony After Acute Myocardial Infarction, Assessed by a Tagging Magnetic Resonance Image Derived Metric, as a Determinant of Ventricular Remodeling
04 May 2009
Development of left ventricular (LV) remodeling after acute myocardial infarction (AMI) is a serious medical complication. We investigated the correlation of LV dyssynchrony after AMI with LV remodeli...
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Sung-A. Chang,
Hyuk-Jae Chang,
Sang Il Choi,
Eun Ju Chun,
Yeonyee E. Yoon,
Hyung-Kwan Kim,
Yong-Jin Kim,
Dong-Ju Choi,
Dae-Won Sohn,
Robert H. Helm,
Albert C. Lardo
et al.
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Full-length article
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pages 19-23
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Cardiogenic Shock Without Flow-Limiting Angiographic Coronary Artery Disease—(from the Should We Emergently Revascularize Occluded Coronary Arteries for Cardiogenic Shock Trial and Registry)
04 May 2009
Myocardial infarction often develops when thrombosis occurs at lesions that have not previously been flow limiting. However, the development of cardiogenic shock complicating acute myocardial infarcti...
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John K. French,
Shannon Harkness,
Lynn Sleeper,
S. Chiu Wong,
Jacques Col,
Vladimir Dzavik,
Harvey D. White,
Judith S. Hochman
et al.
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Full-length article
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pages 24-28
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Safety and Efficacy of Achieving Very Low Low-Density Lipoprotein Cholesterol Levels With Rosuvastatin 40 mg Daily (from the ASTEROID Study)
05 May 2009
Clinical trial evidence supports the use of intensive statin therapy for patients with coronary artery disease. High doses of potent statins have shown the greatest clinical benefit, but concerns pers...
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Stephen D. Wiviott,
Satishkumar Mohanavelu,
Joel S. Raichlen,
Valerie A. Cain,
Steven E. Nissen,
Peter Libby
et al.
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Full-length article
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pages 29-35
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Timing and Duration of Myocardial Ischemia on Holter Monitoring Following Percutaneous Coronary Intervention and Their Association With Clinical Outcomes (a PROTECT-TIMI 30 Substudy Analysis)
04 May 2009
In patients with unstable angina, evidence of myocardial ischemia on Holter monitoring is associated with an adverse prognosis. However, the association of duration and timing of ischemia on Holter mo...
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C. Michael Gibson,
Yuri B. Pride,
Jacqueline L. Buros,
Lauren N. Ciaglo,
David A. Morrow,
Benjamin M. Scirica,
Peter H. Stone,
TIMI Study Group
et al.
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Full-length article
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pages 36-40
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Prognostic Value of Hemoglobin A1C Levels in Patients With Diabetes Mellitus Undergoing Percutaneous Coronary Intervention With Stent Implantation
The optimal glycosylated hemoglobin (HbA1C) target in diabetic patients is a subject of ongoing controversy that may be especially pertinent in diabetic patients with coronary artery disease. This stu...
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Gilles Lemesle,
Laurent Bonello,
Axel de Labriolle,
Gabriel Maluenda,
Asmir I. Syed,
Sara D. Collins,
Itsik Ben-Dor,
Rebecca Torguson,
Kimberly Kaneshige,
Zhenyi Xue,
William O. Suddath,
Lowell F. Satler,
Kenneth M. Kent,
Joseph Lindsay,
Augusto D. Pichard,
Ron Waksman
et al.
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Full-length article
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pages 41-45
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Relation of Genetic Polymorphisms in the Cytochrome P450 Gene With Clopidogrel Resistance After Drug-Eluting Stent Implantation in Koreans
04 May 2009
Clopidogrel is a prodrug that has to be converted to an active metabolite by hepatic cytochrome P450 (CYP) isoenzymes to inhibit platelet aggregation. Individual variability of platelet inhibition by ...
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Jung Myung Lee,
Sungha Park,
Dong-Jik Shin,
Donghoon Choi,
Chi Young Shim,
Young-Guk Ko,
Jung-Sun Kim,
Eun-Soon Shin,
Chong Won Chang,
Jong-Eun Lee,
Yangsoo Jang
et al.
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Full-length article
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pages 46-51
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Relation of Severe Coronary Artery Narrowing to Insulin or Thiazolidinedione Use in Patients With Type 2 Diabetes Mellitus (from the Bypass Angioplasty Revascularization Investigation 2 Diabetes Study)
14 May 2009
Patients with diabetes continue to die of coronary artery disease (CAD) at rates 2 to 4 times higher than patients without diabetes, despite advances in treatment of cardiovascular disease. The role o...
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Rodica Pop-Busui,
Manuel Lombardero,
Victor Lavis,
Alan Forker,
Jennifer Green,
Mary Korytkowski,
Burton E. Sobel,
Teresa L.Z. Jones,
BARI 2D Study Group
et al.
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Full-length article
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pages 52-58
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| Editors' Consensus |
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Article Title |
Author(s) |
Type |
Pages |
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The American Journal of Cardiology and Journal of Periodontology Editors' Consensus: Periodontitis and Atherosclerotic Cardiovascular Disease†
This Editors' Consensus is supported by an educational grant from Colgate-Palmolive, Inc., New York, New York, and is based on a meeting of the authors held in Boston, Massachusetts, on January 9, 200...
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Vincent E. Friedewald,
Kenneth S. Kornman,
James D. Beck,
Robert Genco,
Allison Goldfine,
Peter Libby,
Steven Offenbacher,
Paul M. Ridker,
Thomas E. Van Dyke,
William C. Roberts
et al.
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Discussion
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pages 59-68
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| Preventive Cardiology |
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Article Title |
Author(s) |
Type |
Pages |
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Influence of the Metabolic Syndrome Versus the Sum of Its Individual Components on Left Ventricular Geometry in Young Adults (from the Bogalusa Heart Study)
Current preventive cardiology guidelines strongly recommend identification of metabolic syndrome (MS), a constellation of cardiovascular risk factors, in clinical practice. These MS risk factors, indi...
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Dharmendrakumar A. Patel,
Sathanur R. Srinivasan,
Wei Chen,
Gerald S. Berenson
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Full-length article
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pages 69-73
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Flushing Profile of Extended-Release Niacin/Laropiprant Versus Gradually Titrated Niacin Extended-Release in Patients With Dyslipidemia With and Without Ischemic Cardiovascular Disease
Niacin has beneficial effects on a patient's lipid and lipoprotein profiles and cardiovascular risk, particularly at doses >2 g/day, but is underused due to flushing. Laropiprant (LRPT), a selectiv...
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Darbie Maccubbin,
Michael J. Koren,
Michael Davidson,
Dov Gavish,
Richard C. Pasternak,
Geraldine Macdonell,
Madhuja Mallick,
Christine McCrary Sisk,
John F. Paolini,
Yale Mitchel
et al.
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Full-length article
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pages 74-81
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Safety and Tolerability of Dalcetrapib†
Efficacy and safety data for dalcetrapib (RO4607381/JTT-705) are presented, following a report of increased mortality and cardiac events with another cholesteryl ester transfer protein inhibitor, torc...
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Evan A. Stein,
Erik S.G. Stroes,
George Steiner,
Brendan M. Buckley,
Alessandro M. Capponi,
Tracy Burgess,
Eric J. Niesor,
David Kallend,
John J.P. Kastelein
et al.
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Full-length article
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pages 82-91
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| Arrhythmias and Conduction Disturbances |
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Article Title |
Author(s) |
Type |
Pages |
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Relation of Multiple Inflammatory Biomarkers to Incident Atrial Fibrillation
05 May 2009
Basic and clinical studies have suggested that inflammation predisposes to atrial fibrillation (AF). We assessed the association of 12 circulating inflammatory biomarkers (i.e., C-reactive protein, fi...
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Renate B. Schnabel,
Martin G. Larson,
Jennifer F. Yamamoto,
Sekar Kathiresan,
Jian Rong,
Daniel Levy,
John F. Keaney,
Thomas J. Wang,
Ramachandran S. Vasan,
Emelia J. Benjamin
et al.
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Full-length article
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pages 92-96
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Gender Differences of Electrophysiological Characteristics in Focal Atrial Tachycardia
27 April 2009
Gender differences of supraventricular tachycardias such as atrioventricular nodal re-entry, atrioventricular re-entry, and atrial fibrillation have been reported. There is little evidence of the effe...
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Yu-Feng Hu,
Jin-Long Huang,
Tsu-Juey Wu,
Satoshi Higa,
Chun-Ming Shih,
Ching-Tai Tai,
Yenn-Jiang Lin,
Shih-Lin Chang,
Li-Wei Lo,
Tuan Ta-Chuan,
Chien-Jong Chang,
Wen-Chin Tsai,
Pi-Chang Lee,
Hsuan-Ming Tsao,
Sugako Ishigaki,
Asuka Oyakawa,
Shih-Ann Chen
et al.
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Full-length article
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pages 97-100
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| Systemic Hypertension |
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Article Title |
Author(s) |
Type |
Pages |
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Impact of Family Hypertension History on Exercise-Induced Cardiac Remodeling
Left ventricular (LV) hypertrophy is a well-established, but highly variable, finding among exercise-trained persons. The causes for the variability in LV remodeling in response to exercise training r...
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Aaron L. Baggish,
Rory B. Weiner,
Kibar Yared,
Francis Wang,
Eli Kupperman,
Adolph M. Hutter,
Michael H. Picard,
Malissa J. Wood
et al.
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Full-length article
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pages 101-106
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| Heart Failure |
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Article Title |
Author(s) |
Type |
Pages |
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Age- and Gender-Related Differences in Quality of Care and Outcomes of Patients Hospitalized With Heart Failure (from OPTIMIZE-HF)
Previous studies have suggested that female and elderly patients with heart failure (HF) are less likely to receive guideline-recommended therapies, but these studies have involved select patient popu...
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Gregg C. Fonarow,
William T. Abraham,
Nancy M. Albert,
Wendy Gattis Stough,
Mihai Gheorghiade,
Barry H. Greenberg,
Christopher M. O'Connor,
Jie Lena Sun,
Clyde Yancy,
James B. Young,
OPTIMIZE-HF Investigators and Hospitals
et al.
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Full-length article
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pages 107-115
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Long-Term Clinical Response of Cardiac Resynchronization After Chronic Right Ventricular Pacing
27 April 2009
Chronic right ventricular (RV) pacing might elicit unpredictably deleterious effects on left ventricular (LV) function similar to that of native left bundle branch block (LBBB). The objective of the p...
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Peter Paul H.M. Delnoy,
Jan Paul Ottervanger,
Henk Oude Luttikhuis,
Arif Elvan,
Anand R. Ramdat Misier,
Willem P. Beukema,
Norbert M. van Hemel
et al.
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Full-length article
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pages 116-121
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| Valvular Heart Disease |
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Article Title |
Author(s) |
Type |
Pages |
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Osteoporosis Treatment and Progression of Aortic Stenosis
05 May 2009
A decrease in bone mineral density has been reported to be associated with increased progression of aortic stenosis (AS). We hypothesized that osteoporosis treatment (OT) is associated with decreased ...
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Adam H. Skolnick,
Martin Osranek,
Philip Formica,
Itzhak Kronzon
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Full-length article
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pages 122-124
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| Editorial |
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Article Title |
Author(s) |
Type |
Pages |
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Bone Modifiers and the Quest to Slow Progression of Aortic Stenosis†
21 May 2009
Aortic stenosis (AS) will likely become increasingly frequent with the aging of the American population. The difficulties in treating elderly patients with critical AS emphasize the potential value of...
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Robert E. Goldstein
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Editorial
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pages 125-127
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| Cardiomyopathy |
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Article Title |
Author(s) |
Type |
Pages |
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Ventricular Arrhythmia Following Alcohol Septal Ablation for Obstructive Hypertrophic Cardiomyopathy
05 May 2009
We sought to assess the risk of sudden cardiac death (SCD) and ventricular arrhythmia after alcohol septal ablation (ASA) for obstructive hypertrophic cardiomyopathy. ASA is a nonsurgical alternative ...
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Peter A. Noseworthy,
Michael A. Rosenberg,
Michael A. Fifer,
Igor F. Palacios,
Patricia A. Lowry,
Jeremy N. Ruskin,
Danita M. Sanborn,
Michael H. Picard,
Gus J. Vlahakes,
Theofanie Mela,
Saumya Das
et al.
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Full-length article
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pages 128-132
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Prevalence and Clinical Characteristics of Right Ventricular Dysfunction in Transient Stress Cardiomyopathy
04 May 2009
Transient stress cardiomyopathy (TSC) is a cause of reversible left ventricular (LV) dysfunction that is increasingly recognized. Reports to date have focused primarily on LV involvement, with little ...
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Timothy P. Fitzgibbons,
Christopher Madias,
Adhar Seth,
Joseph L. Bouchard,
Jeffrey T. Kuvin,
Ayan R. Patel,
Natesa G. Pandian,
Theo E. Meyer,
Gerard P. Aurigemma,
Dennis A. Tighe
et al.
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Full-length article
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pages 133-136
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| Miscellaneous |
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Article Title |
Author(s) |
Type |
Pages |
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Plasma N-Terminal Prohormone Brain Natriuretic Peptide as a Marker for Postoperative Cardiac Events in High-Risk Patients Undergoing Noncardiac Surgery
14 May 2009
This study considered if N-terminal prohormone brain natriuretic peptide (NT–proBNP) is associated with increased risk for postoperative cardiac events in high-risk patients undergoing noncardiac surg...
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Robert Clark Schutt,
Cihan Cevik,
Michael P. Phy
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Full-length article
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pages 137-140
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| Review |
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Article Title |
Author(s) |
Type |
Pages |
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Meta-Analysis of Adverse Cardiovascular Outcomes Associated With Antecedent Hypertension After Myocardial Infarction
04 May 2009
The aim of this study was to investigate the association of antecedent hypertension with adverse cardiovascular outcomes after myocardial infarction. A search of Medline and EMBASE was supplemented by...
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Guanmin Chen,
Brenda Hemmelgarn,
Sami Alhaider,
Hude Quan,
Norm Campbell,
Doreen Rabi
et al.
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Review article
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pages 141-147
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| Case Report |
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Article Title |
Author(s) |
Type |
Pages |
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Relation Between Inheritance of Cyanotic Congenital Heart Disease and Persistent Foramen Ovale
04 May 2009
Cyanotic congenital heart disease (CCHD) usually occurs sporadically, but occasionally it is familial without evidence of Mendelian inheritance. The investigators previously reported an association be...
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Peter Wilmshurst,
Jane Panikkar,
Matthew Pearson,
Simon Nightingale
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Full-length article
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pages 148-149
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| Frontmatter |
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Article Title |
Author(s) |
Type |
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Editorial Board
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Editorial board
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page A2
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Contents
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Contents list
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pages A4-A6
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