| Coronary Artery Disease |
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Article Title |
Author(s) |
Type |
Pages |
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Severity of Coronary Arterial Stenoses Responsible for Acute Coronary Syndromes
16 March 2009
Acute myocardial infarctions were generally believed to result from plaque rupture and thrombosis at the site of a “mild to moderate” coronary stenosis. To assess the severity of coronary stenoses tha...
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Ganesh Manoharan,
Argyrios Ntalianis,
Olivier Muller,
Michailis Hamilos,
Giovanna Sarno,
Narbeh Melikian,
Marc Vanderheyden,
Guy R. Heyndrickx,
Eric Wyffels,
William Wijns,
Bernard De Bruyne
et al.
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Full-length article
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pages 1183-1188
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Incidence, Predictors, and Outcome of New, Subsequent Lesions Treated With Percutaneous Coronary Intervention in Patients Presenting With Myocardial Infarction
16 March 2009
Despite improving strategies for control of risk factors, progression of atherosclerosis may lead to recurrent cardiac events related to a lesion other than that treated with initial percutaneous coro...
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Gilles Lemesle,
Axel de Labriolle,
Laurent Bonello,
Rebecca Torguson,
Kimberly Kaneshige,
Zehnyi Xue,
William O. Suddath,
Lowell F. Satler,
Kenneth M. Kent,
Joseph Lindsay,
Augusto D. Pichard,
Ron Waksman
et al.
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Full-length article
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pages 1189-1195
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Impact of Gender and Antithrombin Strategy on Early and Late Clinical Outcomes in Patients With Non–ST-Elevation Acute Coronary Syndromes (from the ACUITY Trial)
Women with non–ST-elevation acute coronary syndrome are at increased risk for ischemic and bleeding complications compared with men. We examined the impact of gender and antithrombotic therapy for non...
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Alexandra J. Lansky,
Roxana Mehran,
Ecatarina Cristea,
Helen Parise,
Frederick Feit,
E. Magnus Ohman,
Harvey D. White,
Karen P. Alexander,
Michel E. Bertrand,
Walter Desmet,
Martial Hamon,
Gregg W. Stone
et al.
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Full-length article
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pages 1196-1203
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| Editorial |
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Article Title |
Author(s) |
Type |
Pages |
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Acute Myocardial Infarction and Underlying Stenosis Severity
09 March 2009
Acute myocardial infarction often occurs as a result of plaque rupture or plaque erosion of a so-called vulnerable plaque. It is generally believed by many cardiologists that such vulnerable plaque mo...
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Nico H.J. Pijls
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Discussion
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pages 1204-1205
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| Coronary Artery Disease |
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Article Title |
Author(s) |
Type |
Pages |
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Predicting Irreversible Left Ventricular Dysfunction After Acute Myocardial Infarction
Patients with reduced left ventricular ejection fractions (LVEFs) and previous myocardial infarctions or heart failure are at increased mortality risk. Implantable cardioverter-defibrillators may miti...
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Daniel R. Frisch,
Evaldas Giedrimas,
Satishkumar Mohanavelu,
Amy Shui,
Kalon K.L. Ho,
C. Michael Gibson,
Mark E. Josephson,
Peter J. Zimetbaum
et al.
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Full-length article
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pages 1206-1209
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Impact of Gender and Age on In Vivo Virtual Histology–Intravascular Ultrasound Imaging Plaque Characterization (from the global Virtual Histology Intravascular Ultrasound [VH-IVUS] Registry)
16 March 2009
Virtual histology intravascular ultrasound (VH-IVUS) analyses were performed in the first 990 patients enrolled in the 3,000+ patient global VH-IVUS Registry to assess the impact of gender and age on ...
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Jie Qian,
Akiko Maehara,
Gary S. Mintz,
M. Pauliina Margolis,
Amir Lerman,
Jason Rogers,
Shuel Banai,
Samer Kazziha,
Celia Castellanos,
Lokesh Dani,
Martin Fahy,
Gregg W. Stone,
Martin B. Leon
et al.
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Full-length article
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pages 1210-1214
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Prevalence of Coronary Heart Disease in Patients With Aortic Aneurysm and/or Peripheral Artery Disease
Although the presence of coronary heart disease (CHD) was the major determinant of perioperative mortality and long-term prognosis in patients with aortic aneurysm (AA) and peripheral artery disease (...
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Kenichi Hirose,
Taishiro Chikamori,
Satoshi Hida,
Hirokazu Tanaka,
Yuko Igarashi,
Yoshiko Watanabe,
Nobusato Koizumi,
Satoshi Kawaguchi,
Yukio Obitsu,
Hiroshi Shigematsu,
Akira Yamashina
et al.
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Full-length article
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pages 1215-1220
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Impact of Plaque Characteristics Analyzed by Intravascular Ultrasound on Long-Term Clinical Outcomes
06 March 2009
Limited data are available on long-term outcomes for vulnerable plaque analyzed by intravascular ultrasound (IVUS). The aim of this study was to investigate long-term clinical outcomes in 183 patients...
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Sung-Hwan Kim,
Myeong-Ki Hong,
Duk-Woo Park,
Seung-Whan Lee,
Young-Hak Kim,
Cheol Whan Lee,
Jae-Joong Kim,
Seong-Wook Park,
Seung-Jung Park
et al.
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Full-length article
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pages 1221-1226
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| Review |
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Article Title |
Author(s) |
Type |
Pages |
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An Evidence-Based Review of the Cardiovascular Risks of Nonsteroidal Anti-Inflammatory Drugs
Nonsteroidal anti-inflammatory drugs (NSAIDs), both nonselective and cyclooxygenase-2–specific inhibitors, are commonly used medications for the relief of acute and chronic pain associated with a wide...
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Michael E. Farkouh,
Bruce P. Greenberg
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Review article
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pages 1227-1237
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| Preventive Cardiology |
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Article Title |
Author(s) |
Type |
Pages |
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Associations of Dietary Long-Chain n-3 Polyunsaturated Fatty Acids and Fish With Biomarkers of Inflammation and Endothelial Activation (from the Multi-Ethnic Study of Atherosclerosis [MESA])
06 March 2009
The cardioprotective effects of long-chain n-3 polyunsaturated fatty acids (PUFAs) and fish consumption have been observed. However, data on the specific associations of these dietary factors with inf...
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Ka He,
Kiang Liu,
Martha L. Daviglus,
Nancy Swords Jenny,
Elizabeth Mayer-Davis,
Rui Jiang,
Lyn Steffen,
David Siscovick,
Michael Tsai,
David Herrington
et al.
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Full-length article
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pages 1238-1243
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| Arrhythmias and Conduction Disturbances |
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Article Title |
Author(s) |
Type |
Pages |
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Relation of Increased Short-Term Variability of QT Interval to Congenital Long-QT Syndrome
20 March 2009
Apart from clinical symptoms the diagnosis and risk stratification in long-QT syndrome (LQTS) is usually based on the surface electrocardiogram. Studies have indicated that not only prolongation of th...
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Martin Hinterseer,
Britt-Maria Beckmann,
Morten B. Thomsen,
Arne Pfeufer,
Robert Dalla Pozza,
Markus Loeff,
Heinrich Netz,
Gerhard Steinbeck,
Marc A. Vos,
Stefan Kääb
et al.
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Full-length article
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pages 1244-1248
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Comparison of Characteristics and Significance of Immediate Versus Early Versus No Recurrence of Atrial Fibrillation After Catheter Ablation
09 March 2009
Atrial fibrillation (AF) recurrences after catheter ablation are common within the first month after AF ablation, and inflammatory processes may be related to AF genesis. This study aimed to clarify t...
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Takashi Koyama,
Yukio Sekiguchi,
Hiroshi Tada,
Takanori Arimoto,
Hiro Yamasaki,
Kenji Kuroki,
Takeshi Machino,
Kazuko Tajiri,
Xu Dong Zhu,
Miyako Kanemoto,
Aiko Sugiyasu,
Keisuke Kuga,
Kazutaka Aonuma
et al.
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Full-length article
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pages 1249-1254
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| Systemic Hypertension |
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Article Title |
Author(s) |
Type |
Pages |
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Relation of Plasma Midregional Proatrial Natriuretic Peptide to Target Organ Damage in Adults With Systemic Hypertension
20 March 2009
We tested the hypothesis that, in adults with essential hypertension, plasma levels of midregional proatrial natriuretic peptide (MR-proANP) are associated with target organ damage. MR-proANP is a new...
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Mahyar Khaleghi,
Malik A. Al-Omari,
Venkateswarlu Kondragunta,
Nils G. Morgenthaler,
Joachim Struck,
Andreas Bergmann,
Thomas H. Mosley,
Iftikhar J. Kullo
et al.
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Full-length article
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pages 1255-1260
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| Heart Failure |
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Article Title |
Author(s) |
Type |
Pages |
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Effects of Left Ventricular Volume Overload on Mitochondrial and Death-Receptor–Mediated Apoptotic Pathways in the Transition to Heart Failure
Cardiomyocyte apoptosis has been implicated in the pathogenesis of heart failure (HF). This study was performed in patients with left ventricular (LV) volume overload at different stages in the develo...
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Narain Moorjani,
Stephen Westaby,
Jagat Narula,
Pedro A. Catarino,
Robin Brittin,
Tim J. Kemp,
Navneet Narula,
Peter H. Sugden
et al.
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Full-length article
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pages 1261-1268
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Usefulness of Myeloperoxidase Levels in Healthy Elderly Subjects to Predict Risk of Developing Heart Failure
16 March 2009
Increased systemic myeloperoxidase (MPO) has been associated with both the presence and severity of heart failure (HF). This study tested the hypothesis that increased systemic MPO in apparently healt...
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W.H. Wilson Tang,
Ronit Katz,
Marie-Luise Brennan,
Ronnier J. Aviles,
Russell P. Tracy,
Bruce M. Psaty,
Stanley L. Hazen
et al.
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Full-length article
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pages 1269-1274
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Usefulness of a Combination of Systolic Function by Left Ventricular Ejection Fraction and Diastolic Function by E/E′ to Predict Prognosis in Patients With Heart Failure
09 March 2009
Left ventricular (LV) ejection fraction (EF) was known as a conventional predictor of heart failure (HF). However, early transmitral flow velocity (E)/early diastolic velocity of mitral annulus (E′) c...
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Kumiko Hirata,
Eiichi Hyodo,
Takeshi Hozumi,
Ryoichi Kita,
Makoto Hirose,
Yuji Sakanoue,
Yukio Nishida,
Takahiko Kawarabayashi,
Minoru Yoshiyama,
Junichi Yoshikawa,
Takashi Akasaka
et al.
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Full-length article
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pages 1275-1279
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Effect of Long-Term Resynchronization Therapy on Left Ventricular Remodeling in Pacemaker Patients Upgraded to Biventricular Devices
Right ventricular pacing resulted in abnormal ventricular depolarization and an activation pattern similar to left branch bundle block. In some circumstances, it may exacerbate symptoms of heart failu...
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Mehmet Akif Vatankulu,
Omer Goktekin,
Mehmet Gurkan Kaya,
Selim Ayhan,
Zekeriya Kucukdurmaz,
Richard Sutton,
Michael Henein
et al.
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Full-length article
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pages 1280-1284
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Relation of Depression to Severity of Illness in Heart Failure (from Heart Failure And a Controlled Trial Investigating Outcomes of Exercise Training [HF-ACTION])
02 March 2009
Depression is common in patients with heart failure (HF), prognostic for adverse outcomes and purportedly related to disease severity. Psychological and physiologic factors relevant to HF were assesse...
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Stephen S. Gottlieb,
Willem J. Kop,
Stephen J. Ellis,
Philip Binkley,
Jonathan Howlett,
Christopher O'Connor,
James A. Blumenthal,
Gerald Fletcher,
Ann M. Swank,
Lawton Cooper,
HF-ACTION Investigators
et al.
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Full-length article
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pages 1285-1289
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Usefulness of Heart Rate as an Independent Predictor for Survival After Heart Transplantation
16 March 2009
It was unclear whether increased heart rate (HR) increased long-term mortality after heart transplantation (HT). The aim of this study was to evaluate whether HR predicted survival after HT. A retrosp...
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Rishi G. Anand,
Madhavi T. Reddy,
C.L. Yau,
Leann Myers,
Rohit R. Amin,
Paul F. Stahls,
Debbie Dumas,
Edward D. Frohlich,
Hector O. Ventura
et al.
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Full-length article
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pages 1290-1294
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| Valvular Heart Disease |
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Article Title |
Author(s) |
Type |
Pages |
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Role of Multislice Computed Tomography in Transcatheter Aortic Valve Replacement
Transcatheter aortic valve replacement (TAVR) required precise knowledge of the anatomic dimensions and physical characteristics of the aortic valve, annulus, and aortic root. Most groups currently us...
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David A. Wood,
Laurens F. Tops,
John R. Mayo,
Sanjeevan Pasupati,
Martin J. Schalij,
Karin Humphries,
May Lee,
Abdullah Al Ali,
Brad Munt,
Rob Moss,
Christopher R. Thompson,
Jeroen J. Bax,
John G. Webb
et al.
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Full-length article
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pages 1295-1301
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| Cardiomyopathy |
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Article Title |
Author(s) |
Type |
Pages |
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Electrocardiographic Pattern in Arrhythmogenic Right Ventricular Cardiomyopathy
20 March 2009
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a cardiac disease characterized by progressive myocardial atrophy and fibrofatty replacement. Standard electrocardiograms (ECGs) and signal-av...
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Alexandros Klavdios Steriotis,
Barbara Bauce,
Luciano Daliento,
Ilaria Rigato,
Elisa Mazzotti,
Antonio Franco Folino,
Martina Perazzolo Marra,
Luca Brugnaro,
Andrea Nava
et al.
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Full-length article
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pages 1302-1308
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| Congenital Heart Disease |
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Article Title |
Author(s) |
Type |
Pages |
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Effect of Bosentan on Exercise Capacity and Quality of Life in Adults With Pulmonary Arterial Hypertension Associated With Congenital Heart Disease With and Without Down's Syndrome
16 March 2009
Pulmonary arterial hypertension associated with congenital heart disease caused by systemic-to-pulmonary shunting was associated with a high risk of morbidity and mortality. In this retrospective stud...
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Mariëlle G.J. Duffels,
Jeroen C. Vis,
Rosa L.E. van Loon,
Pythia T. Nieuwkerk,
Arie P.J. van Dijk,
Elke S. Hoendermis,
Rianne H.A.C.M. de Bruin-Bon,
Berto J. Bouma,
Paul Bresser,
Rolf M.F. Berger,
Barbara J.M. Mulder
et al.
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Full-length article
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pages 1309-1315
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| Editorials |
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Article Title |
Author(s) |
Type |
Pages |
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Clinical and Research Applications of Carotid Intima-Media Thickness
16 March 2009
Cardiovascular imaging modalities such as coronary computed tomography, carotid ultrasonography, and cardiovascular magnetic resonance imaging are increasingly being used to measure cardiovascular dis...
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Kavita Sharma,
Michael J. Blaha,
Roger S. Blumenthal,
Kiran Musunuru
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Editorial
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pages 1316-1320
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Utility of Ezetimibe
09 March 2009
Ezetimibe is the first of a new class of drugs that inhibit cholesterol absorption through the proximal small intestine. It provides an additional 15% to 20% reduction in low-density lipoprotein (LDL)...
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Hiroshi Ashikaga,
Roger S. Blumenthal,
Steven R. Jones
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Editorial
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pages 1321-1322
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The Extrapolation of Study Results in the Device Approval Process
16 March 2009
The US Food and Drug Administration's (FDA) Circulatory System Devices Panel met on November 20, 2008, to make recommendations on the NaviStar ThermoCool irrigated radiofrequency ablation catheter (Bi...
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John C. Somberg
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Editorial
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pages 1323-1324
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| From the Editor |
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Article Title |
Author(s) |
Type |
Pages |
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Evaluating Lipid-Lowering Trials in the Twenty-First Century
It's these large, multicenter, double-blind, often placebo-controlled clinical trials that have the greatest impact on how medicine now is practiced. With lipid-lowering drugs, the trials are of 2 bas...
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William Clifford Roberts
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Editorial
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pages 1325-1328
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| Readers' Comments |
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Article Title |
Author(s) |
Type |
Pages |
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Proper Testing for Myocardial Ischemia in Firefighters
We agree with Angerer et al that submaximal treadmill exercise testing in the evaluation of candidates for firefighting (and other public safety duty) does not adequately simulate the thermal and hemo...
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Lawrence W. Raymond,
Thomas A. Barringer
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Correspondence
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page 1329
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Prognostic Values of Various Markers in Evaluation of Patients With Chest Pain
I was quite impressed by the study of McCann et al in their attempt to use a multimarker approach to determine 1-year prognoses, using the end point of death or acute myocardial infarction, in patient...
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David S. David
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Correspondence
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pages 1329-1330
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Arterial Age as a Function of Coronary Artery Calcium
We commend McClelland et al on their development of a practical tool (already available to clinicians online) that translates the coronary calcium score (CCS) into an arterial age, which is then subst...
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Thomas Barringer,
William Cromwell
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Correspondence
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pages 1330-1331
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In ST-Elevation Myocardial Infarction Patients Receiving Primary Percutaneous Coronary Intervention, Admission Cardiac Troponin T and Peak Cardiac Troponin T Values Differ in Their Prognostic Properties
We read with interest the study by Hassan et al investigating the ability of peak cardiac troponin T (cTnT) to predict infarct size and long-term outcomes after ST elevation myocardial infarctions in ...
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Jonas Hallén,
Dan Atar
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Correspondence
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page 1331
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β-Blocker Use and the Development of Depression
We read with interest the report by Papademetriou in which the investigator reported the effects of nebivolol for the treatment of hypertension in a sample of 845 subjects. Papademetriou observed that...
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Joost P. van Melle,
Peter de Jonge
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Correspondence
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pages 1331-1332
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The Clinical Dilemma of Positive Results of High-Sensitive Troponin Assays
Since the widespread introduction of highly sensitive assays for troponin testing, it is likely that the number of patients presenting with values exceeding the limit of detection and the recommended ...
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Giuseppe Lippi,
Martina Montagnana,
Gian Cesare Guidi
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Correspondence
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page 1332
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Erratum
Erratum for Sharma M, et al., “Safety of Cardiac Catheterization in Patients With End-Stage Liver Disease Awaiting Liver Transplantation,” Am J Cardiol 2009;103:742–746
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Erratum
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page 1332
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| Frontmatter |
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Article Title |
Author(s) |
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Editorial Board
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Editorial board
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page A2
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Contents
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Contents list
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page A4
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