| Coronary Artery Disease |
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Impact of Body Mass Index and Waist-to-Hip Ratio on Clinical Outcomes in Patients With ST-Segment Elevation Acute Myocardial Infarction (from the Korean Acute Myocardial Infarction Registry)
28 July 2008
The relation between body mass index (BMI) and waist-to-hip ratio (WHR) to clinical outcomes in patients with ST-segment elevation acute myocardial infarction (MI) has not been well described. As part...
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Sang-Hee Lee,
Jong-Seon Park,
Woong Kim,
Dong-Gu Shin,
Young-Jo Kim,
Dong-Su Kim,
Dong-Ju Choi,
Kyoo-Rok Han,
Chong-Jin Kim,
Myeong-Chan Cho,
Shung-Chull Chae,
Myung-Ho Jeong,
Korean Acute Myocardial Infarction Registry Investigators
et al.
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Full-length article
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pages 957-965
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Prevalent Cocaine Use and Myocardial Infarction
07 August 2008
Studies have reported a possible link between cocaine use and risk for cardiovascular events. The aim of this study was to examine the association between self-reported cocaine use and physician-diagn...
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Stella Aslibekyan,
Emily B. Levitan,
Murray A. Mittleman
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Full-length article
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pages 966-969
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Comparison of Peripheral Arterial Response to Mental Stress in Men Versus Women With Coronary Artery Disease
28 July 2008
There are profound gender-related differences in the incidence, presentation, and outcomes of coronary artery disease (CAD). These differences are not entirely explained by traditional cardiovascular ...
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Mustafa Hassan,
Qin Li,
Babette Brumback,
Dorian G. Lucey,
Melinda Bestland,
Gina Eubanks,
Roger B. Fillingim,
David S. Sheps
et al.
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Full-length article
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pages 970-974
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Distribution and Frequency of Thin-Capped Fibroatheromas and Ruptured Plaques in the Entire Culprit Coronary Artery in Patients With Acute Coronary Syndrome as Determined by Optical Coherence Tomography
04 August 2008
The aim of this study was to investigate the distribution and frequency of thin-capped fibroatheromas (TCFAs) within the entire length of culprit coronary arteries in patients with acute coronary synd...
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Atsushi Tanaka,
Toshio Imanishi,
Hironori Kitabata,
Takashi Kubo,
Shigeho Takarada,
Hideaki Kataiwa,
Akio Kuroi,
Hiroto Tsujioka,
Takashi Tanimoto,
Nobuo Nakamura,
Masato Mizukoshi,
Kumiko Hirata,
Takashi Akasaka
et al.
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Full-length article
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pages 975-979
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Quantitative Automated Assessment of Myocardial Perfusion at Cardiac Catheterization†
28 July 2008
Perfusion assessed in the cardiac catheterization laboratory predicts outcomes after myocardial infarction. The aim of this study was to investigate a novel method of assessing perfusion using digital...
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Andrew J. Boyle,
Karl H. Schuleri,
Jean Lienard,
Regis Vaillant,
Michael Y. Chan,
Jeffrey M. Zimmet,
Ramesh Mazhari,
Marco Centola,
Gary Feigenbaum,
Joud Dib,
Navin K. Kapur,
Joshua M. Hare,
Jon R. Resar
et al.
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Full-length article
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pages 980-987
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Comparison of 64-Slice Multidetector Computed Tomography With Spectral Analysis of Intravascular Ultrasound Backscatter Signals for Characterizations of Noncalcified Coronary Arterial Plaques
28 July 2008
In vivo identification of plaque composition may allow the detection of vulnerable plaques before rupture. However, the clinical relevance of multidetector computed tomography (MDCT) in characterizing...
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Byoung-Joo Choi,
Doo-Kyoung Kang,
Seung-Jea Tahk,
So-Yeon Choi,
Myeong-Ho Yoon,
Hong-Seok Lim,
Soo-Jin Kang,
Hyoung-Mo Yang,
Jin-Sun Park,
Mingri Zheng,
Gyo-Seung Hwang,
Joon-Han Shin
et al.
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Full-length article
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pages 988-993
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Comparison of Intravascular Ultrasound to Contrast-Enhanced 64-Slice Computed Tomography to Assess the Significance of Angiographically Ambiguous Coronary Narrowings
04 August 2008
The efficacy of contrast-enhanced multislice computed tomography (MSCT) for assessment of ambiguous lesions is unknown. We compared both quantitative coronary angiography (QCA) and MSCT to the gold st...
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Teruo Okabe,
Wm. Guy Weigold,
Gary S. Mintz,
Robert Roswell,
Subodh Joshi,
Sung Yun Lee,
Bongryeol Lee,
Daniel H. Steinberg,
Probal Roy,
Tina L. Pinto Slottow,
Kimberly Smith,
Rebecca Torguson,
Zhenyi Xue,
Lowell F. Satler,
Kenneth M. Kent,
Augusto D. Pichard,
Neil J. Weissman,
Joseph Lindsay,
Ron Waksman
et al.
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Full-length article
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pages 994-1001
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Clinical and Angiographic Follow-Up of Small Vessel Lesions Treated With Paclitaxel-Eluting Stents (from the TRUE Registry)
28 July 2008
Several randomized trials have shown that sirolimus-eluting stents and paclitaxel-eluting stents (PES) are effective in reducing restenosis in respect to bare-metal stents, including the subset of sma...
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Cosmo Godino,
Shinichi Furuichi,
Azeem Latib,
Nuccia Morici,
Alaide Chieffo,
Enrico Romagnoli,
Corrado Tamburino,
Rossella Barbagallo,
Michela Cera,
David Antoniucci,
Omer Goktekin,
Carlo Di Mario,
Bernard Reimers,
Eberhard Grube,
Flavio Airoldi,
Giuseppe M. Sangiorgi,
Antonio Colombo
et al.
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Full-length article
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pages 1002-1008
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Impact of Mild or Moderate Renal Insufficiency on the Intravascular Ultrasonic Analysis of Chronic Vascular Response to Paclitaxel-Eluting and Bare-Metal Stents (from the TAXUS IV, V, and VI Trials)
28 July 2008
The presence of even mild renal insufficiency is usually associated with an increased rate of cardiovascular events after coronary stenting. The aim of this study was to evaluate the impact of mild to...
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Jiro Aoki,
Gary S. Mintz,
Neil J. Weissman,
Lazar Mandinov,
Eberhard Grube,
Keith D. Dawkins,
Stephen G. Ellis,
Joel Greenberg,
Alan Yu,
J. Tift Mann,
Louis Cannon,
Patrick A. Cambier,
Gregg W. Stone
et al.
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Full-length article
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pages 1009-1016
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Effect of Prolonged Thienopyridine Use After Drug-Eluting Stent Implantation (from the TAXUS Landmark Trials Data)
28 July 2008
Previous observational studies have evaluated the utility of prolonged thienopyridine therapy in patients receiving drug-eluting stents, with conflicting results. A landmark analysis was therefore per...
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Gregg W. Stone,
Stephen G. Ellis,
Antonio Colombo,
Eberhard Grube,
Keith D. Dawkins,
Mark Friedman,
Donald S. Baim
et al.
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Full-length article
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pages 1017-1022
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Pleiotropic Effect of Lovastatin, With and Without Cholestyramine, in the Post Coronary Artery Bypass Graft (Post CABG) Trial
11 August 2008
This study evaluated patients in the Post Coronary Artery Bypass Graft (Post CABG) trial for evidence of statin pleiotropic effects in preventing atherosclerotic progression in saphenous vein grafts (...
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Michael Domanski,
Xin Tian,
Jerome Fleg,
Sean Coady,
Christine Gosen,
Ruth Kirby,
Vandana Sachdev,
Genell Knatterud,
Eugene Braunwald
et al.
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Full-length article
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pages 1023-1027
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| Preventive Cardiology |
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Relation of Exercise Capacity and Body Mass Index to Mortality in Patients With Intermediate to High Risk of Coronary Artery Disease
04 August 2008
The relative impact of body mass index (BMI) and exercise capacity on mortality in patients with an intermediate to high likelihood of coronary artery disease (CAD) is not clear. Thus, the effect of B...
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Nils P. Johnson,
Edwin Wu,
Robert O. Bonow,
Thomas A. Holly
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Full-length article
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pages 1028-1033
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Relation of Educational Level to Inflammation-Sensitive Biomarker Level
28 July 2008
It is a well-established finding that cardiovascular morbidity varies among groups of different socioeconomic status. Inflammatory processes have been proposed as a possible mediator of this variance....
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Arie Steinvil,
Arie Shirom,
Samuel Melamed,
Sharon Toker,
Dan Justo,
Nili Saar,
Itzhak Shapira,
Shlomo Berliner,
Ori Rogowski
et al.
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Full-length article
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pages 1034-1039
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Effectiveness of Combined Statin Plus Omega-3 Fatty Acid Therapy for Mixed Dyslipidemia
04 August 2008
Combination therapy for the treatment of dyslipidemia and reduction of cardiovascular risk has been demonstrated to beneficially modify the lipid profile in multiple randomized clinical trials. As rep...
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Philip Barter,
Henry N. Ginsberg
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Review article
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pages 1040-1045
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| Roundtable Discussion (CME) |
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Author(s) |
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The Editor's Roundtable: Nonsteroidal Antiinflammatory Drugs and Cardiovascular Risk
This CME activity is supported by an educational grant from Pfizer, New York, New York.
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Vincent E. Friedewald,
Joel S. Bennett,
Milton Packer,
William C. Roberts,
Gary W. Williams
et al.
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Discussion
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pages 1046-1055
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| Arrhythmias and Conduction Disturbances |
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Relation of Atrial Fibrillation to Glomerular Filtration Rate
28 July 2008
Although both atrial fibrillation (AF) and decreasing glomerular filtration rate (GFR) are strongly related to advanced age and share common associated vascular risk factors, few studies have explored...
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Yasuyuki Iguchi,
Kazumi Kimura,
Kazuto Kobayashi,
Junya Aoki,
Yuka Terasawa,
Kenichiro Sakai,
Junichi Uemura,
Kensaku Shibazaki
et al.
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Full-length article
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pages 1056-1059
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Vasodilation in Vasovagal Syncope and the Effect of Water Ingestion
04 August 2008
Abnormal (increased, but also decreased) vasodilative responses have been observed in patients with vasovagal syncope (VVS). The objective was to assess reactive vasodilation in supine patients with V...
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Panayota Flevari,
Katerina Fountoulaki,
Dionyssios Leftheriotis,
Christophoros Komporozos,
John Lekakis,
Dimitrios Kremastinos
et al.
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Full-length article
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pages 1060-1063
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| Heart Failure |
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Author(s) |
Type |
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Impact of Sleep-Disordered Breathing on Life-Threatening Ventricular Arrhythmia in Heart Failure Patients With Implantable Cardioverter-Defibrillator
28 July 2008
It was recognized that sleep-disordered breathing (SDB) is associated with cardiac arrhythmia and sudden cardiac death. However, it was unclear whether the presence of SDB increased the risk of life-t...
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Naoki Serizawa,
Dai Yumino,
Katsuya Kajimoto,
Yoshimi Tagawa,
Atsushi Takagi,
Morio Shoda,
Hiroshi Kasanuki,
Nobuhisa Hagiwara
et al.
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Full-length article
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pages 1064-1068
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Comparison of Blood Volume Characteristics in Anemic Patients With Low Versus Preserved Left Ventricular Ejection Fractions
04 August 2008
Anemia is a significant co-morbidity in patients with heart failure (HF) irrespective of the ejection fraction and is routinely quantified by hemoglobin concentration. Hemodilution as a cause of anemi...
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Dmitry Abramov,
Rose S. Cohen,
Stuart D. Katz,
Donna Mancini,
Mathew S. Maurer
et al.
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Full-length article
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pages 1069-1072
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Predicting Effects of Exercise Training in Patients With Heart Failure Secondary to Ischemic or Idiopathic Dilated Cardiomyopathy
28 July 2008
The purpose of this study was to investigate which patient characteristics may predict training effects on maximal and submaximal exercise performance in patients with heart failure. Together with com...
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Hareld M. Kemps,
Goof Schep,
Wouter R. de Vries,
Sandor L. Schmikli,
Maria L. Zonderland,
Eric J.M. Thijssen,
Pieter F.F. Wijn,
Pieter A. Doevendans
et al.
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Full-length article
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pages 1073-1078
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| Congenital Heart Disease |
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Exercise Capacity and Participation of Children With a Ventricular Septal Defect
28 July 2008
Existing data on exercise performance in children with a ventricular septal defect (VSD) are scarce and inconclusive. We aimed to elucidate whether and why exercise capacity and physical activity leve...
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Mathijs Binkhorst,
Tom van de Belt,
Marieke de Hoog,
Arie van Dijk,
Michiel Schokking,
Maria Hopman
et al.
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Full-length article
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pages 1079-1084
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Autonomic Heart Rate Control at Rest and During Unloading of the Right Ventricle in Repaired Tetralogy of Fallot in Adolescents
04 August 2008
Arrhythmias in patients with repaired tetralogy of Fallot (ToF) might be due in part to altered autonomic heart rate control caused by altered right ventricle hemodynamics. This study investigated aut...
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Vegard Bruun Wyller,
J. Philip Saul,
Riccardo Barbieri,
Charlotte de Lange,
Einar Hopp,
Ingvild B. Norum,
Erik Thaulow
et al.
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Full-length article
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pages 1085-1089
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| Miscellaneous |
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Significance of Respiratory Artifact in the Electrocardiogram
28 July 2008
Electrocardiographic artifact is generally considered to be a nuisance. Respiratory artifact, however, is a physiologic signal that may carry useful diagnostic information. Our goal was to evaluate th...
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Laszlo Littmann,
Stephen L. Rennyson,
Brian P. Wall,
Jeremy M. Parker
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Full-length article
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pages 1090-1096
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| Methods |
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A Real-Time Three-Dimensional Echocardiographic Quantitative Analysis of Left Atrial Function in Left Ventricular Diastolic Dysfunction
07 August 2008
The evaluation of left ventricular diastolic function provides important information about hemodynamics and has prognostic implications for various cardiac diseases. In particular, left atrial (LA) vo...
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Mitsushige Murata,
Shiro Iwanaga,
Yuichi Tamura,
Makiko Kondo,
Keisuke Kouyama,
Mitsuru Murata,
Satoshi Ogawa
et al.
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Full-length article
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pages 1097-1102
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Heart Rate Response to Adenosine in Patients With Diabetes Mellitus and Normal Myocardial Perfusion Imaging
21 July 2008
Adenosine infusion, as is used in stress single photon-emission computed tomographic (SPECT) imaging, produces an increase in heart rate (HR) and a decrease in blood pressure (BP). The increase in HR ...
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Paco E. Bravo,
Fadi G. Hage,
Ryan M. Woodham,
Jaekyeong Heo,
Ami E. Iskandrian
et al.
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Full-length article
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pages 1103-1106
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| Historical Study |
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Samuel A. Levine and the History of Grading Systolic Murmurs
11 August 2008
Murmurs were described first by Laennec in 1819, after which the significance of a murmur became a matter of debate. By the late 19th century, many physicians regarded systolic murmurs as “organic,” w...
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Mark E. Silverman,
Charles F. Wooley
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Personal report
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pages 1107-1110
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| Case Report |
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Percutaneous, Minimally Invasive Retrieval of a Dislodged and Impacted Device from the Abdominal Aorta, Four Months After Closure of an Atrial Septal Defect
28 July 2008
Four months after the successful implantation of a closure device in a 67-year-old woman with an atrial septal defect, the device was found to be impacted in the abdominal aorta. Severe bouts of only ...
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Philipp Wagdi,
Martin Kunz
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Full-length article
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pages 1111-1112
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| Readers' Comments |
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Article Title |
Author(s) |
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Correct Optimization of Drug-Eluting Stents Should Be Regarded in the Same Light as POETry
We refer to the recent study by Kim et al on the intravascular ultrasound (IVUS) evaluation of optimal drug-eluting stent expansion after using either a semicompliant or a noncompliant balloon. This i...
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Robert Gerber,
Antonio Colombo
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Correspondence
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pages 1113-1114
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Microvolt T-Wave Alternans and Long-Term Prognosis: The Issue of Comparison of the Initial Screening With Repeat Testing Remains Unresolved
The very important contribution of Chan et al in the August 1, 2008, issue of The American Journal of Cardiology reports on an issue long of great concern in the assessment of microvolt T-wave alterna...
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John E. Madias
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Correspondence
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page 1114
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Global Registry of Acute Coronary Events Risk Score
We are surprised to learn in a recent report by Lev et al that the Global Registry of Acute Coronary Events (GRACE) risk score performed so poorly (C index = 0.47). We do not believe it possible the G...
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Joel M. Gore,
Gordon Fitzpatrick
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Correspondence
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page 1114
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Dutch Randomized Trial on Off-Site Primary PCI
In the recent letter, de Boer et al wrote as 3 of the 9 members of the Steering Committee of the partially completed Dutch Randomized Trial on Off-Site Primary PCI, which was a separate study from the...
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J.O.J. Peels,
V.A.W.M. Umans,
J.H. Cornel,
R.W.M. Hautvast,
J.B.R.M. de Swart,
T.P. Wharton
et al.
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Correspondence
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page 1115
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Diabetic Cardiovascular Disease Lost in Translation Between Endocrinology and Cardiology
Maeng et al recently published an analysis of drug-eluting stents (DES) compared with bare-metal stents in diabetes mellitus (DM). In their timely and relevant report, it is disturbing that insulin tr...
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Selcuk Dagdelen
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Correspondence
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pages 1115-1116
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Reflections on the Utility of Imaging for Prevention of Coronary Disease
The expression of frustration about reluctance to endorse the utility of coronary artery calcification scanning expressed by Hecht in The American Journal of Cardiology raises a fundamental question a...
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William B. Kannel,
Ramachandran S. Vasan
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Correspondence
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page 1116
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Does Blood Transfusion Increase Mortality Risk in Acute Myocardial Infarction?
I read with interest the report of Aronson et al regarding the association between red blood cell transfusion and clinical outcomes in patients with acute myocardial infarctions (AMIs). The investigat...
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Wen-Chih Wu
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Correspondence
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pages 1116-1117
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Body Surface Maps and Standard Electrocardiograms in Patients With Acute Myocardial Infarctions: A Paucity of Data from the Posterior Thorax?
In the August 1, 2008, issue of The American Journal of Cardiology, Owens et al reported on a comparison of the performance of their 80-lead body surface maps (BSMs) and that of standard 12-lead elect...
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John E. Madias
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Correspondence
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page 1117
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Oxidized Low-Density Lipoprotein Is Not Equal to Oxidative Stress
We have read the report in The American Journal of Cardiology by Singh et al, who studied the pleiotropic effects of atorvastatin in subjects with metabolic syndrome. Our interest was raised especiall...
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Lambertus J.H. van Tits,
Anton F. Stalenhoef
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Correspondence
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page 1118
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| Frontmatter |
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Editorial Board
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Editorial board
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page A2
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Contents
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Contents list
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page A4
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