| Coronary Artery Disease |
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Inflammatory Markers, Angiographic Severity of Coronary Artery Disease, and Patient Outcome
Serum levels of high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) have been shown to be predictors of adverse outcomes in patients with coronary a...
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Rishi Sukhija,
Ibrahim Fahdi,
Luis Garza,
Louis Fink,
Margaret Scott,
Wady Aude,
Rebecca Pacheco,
Zoran Bursac,
April Grant,
Jawahar L. Mehta
et al.
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Full-length article
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pages 879-884
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Clinical Impact of Metabolic Syndrome and Its Additive Effect With Smoking on Subsequent Cardiac Events After Acute Myocardial Infarction
Little information is available regarding the clinical effect of metabolic syndrome (MS) or its combined effect with smoking on subsequent cardiac events after acute myocardial infarction (AMI). To ex...
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Daisaku Nakatani,
Yasuhiko Sakata,
Hiroshi Sato,
Hiroya Mizuno,
Masahiko Shimizu,
Shinichiro Suna,
Hiroshi Ito,
Yukihiro Koretsune,
Atsushi Hirayama,
Masatsugu Hori,
Osaka Acute Coronary Insufficiency Study (OACIS) Group
et al.
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Full-length article
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pages 885-889
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Serum Complement C3/C4 Ratio, a Novel Marker for Recurrent Cardiovascular Events
Acute coronary syndrome is an inflammatory disease, during which the complement cascade is activated. We assessed the complement C3 and C4 concentration ratio (C3/C4 ratio) in serum as a potential mea...
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Anil Palikhe,
Juha Sinisalo,
Mikko Seppänen,
Heikki Haario,
Seppo Meri,
Ville Valtonen,
Markku S. Nieminen,
Marja-Liisa Lokki
et al.
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Full-length article
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pages 890-895
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Comparison Between Angiography and Fractional Flow Reserve Versus Single-Photon Emission Computed Tomographic Myocardial Perfusion Imaging for Determining Lesion Significance in Patients With Multivessel Coronary Disease
We hypothesized that myocardial perfusion imaging (MPI) would fail to identify all vascular zones with the potential for myocardial ischemia in patients with multivessel coronary disease (MVD). MPI is...
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Michael Ragosta,
Andrew H. Bishop,
Lewis C. Lipson,
Denny D. Watson,
Lawrence W. Gimple,
Ian J. Sarembock,
Eric R. Powers
et al.
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Full-length article
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pages 896-902
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Effects of Atorvastatin on Vitamin D Levels in Patients With Acute Ischemic Heart Disease
Vitamin D deficiency is a risk factor for osteoporosis and other chronic diseases, including type 1 diabetes, hypertension, metabolic syndrome, and ischemic heart disease. Cholesterol and vitamin D sh...
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José L. Pérez-Castrillón,
Gemma Vega,
Laura Abad,
Alberto Sanz,
José Chaves,
Gonzalo Hernandez,
Antonio Dueñas
et al.
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Short communication
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pages 903-905
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Impact of Body Mass Index on Outcomes After Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction
Obesity is a widespread problem, particularly in the cardiovascular disease population. Obese patients have a lower incidence of cardiovascular mortality after elective percutaneous coronary intervent...
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Laxmi Mehta,
William Devlin,
Peter A. McCullough,
William W. O’Neill,
Kimberly A. Skelding,
Gregg W. Stone,
Judith A. Boura,
Cindy L. Grines
et al.
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Full-length article
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pages 906-910
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Safety and Efficacy of the FilterWire EZ in Acute ST-Segment Elevation Myocardial Infarction
Primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) achieves a high epicardial reperfusion rate; however, it is often suboptimal in achieving myocar...
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Victor Guetta,
Morris Mosseri,
Michael Shechter,
Shlomi Matetzky,
Abid Assali,
Yaron Almagor,
Luis Gruberg,
Michal Benderly,
Chaim Lotam,
Ran Kornowski,
UpFlow MI Study Investigators
et al.
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Short communication
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pages 911-915
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Frequency of Slow Coronary Flow Following Successful Stent Implantation and Effect of Nitroprusside
Nitroprusside (NTP) is used for the treatment of slow coronary flow (SCF) after coronary interventions. The wide variation in dosage, route, and timing of its administration in the reported studies pr...
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Flavio Airoldi,
Carlo Briguori,
Domenico Cianflone,
John Cosgrave,
Goran Stankovic,
Cosmo Godino,
Mauro Carlino,
Alaide Chieffo,
Matteo Montorfano,
Marco Mussardo,
Iassen Michev,
Antonio Colombo,
Attilio Maseri
et al.
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Full-length article
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pages 916-920
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Different Thresholds of Myocardial Ischemia in Ramp and Standard Bruce Protocol Exercise Tests in Patients With Positive Exercise Stress Tests and Angiographically Demonstrated Coronary Arterial Narrowing
Gradual instead of abrupt increases in workload favor a more physiologic response in terms of hemodynamic and gas exchange parameters. Therefore, we investigated whether myocardial ischemia is attenua...
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Martin Noël,
Jean Jobin,
Paul Poirier,
Gilles R. Dagenais,
Peter Bogaty
et al.
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Full-length article
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pages 921-924
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Usefulness of 64-Slice Multidetector Computed Tomography in Diagnostic Triage of Patients With Chest Pain and Negative or Nondiagnostic Exercise Treadmill Test Result
The usefulness of 64-slice multidetector coronary computed tomography (MDCT) in a diagnostic triage of 100 consecutive patients (age 55.8 ± 11.6 years; 57% men) with chest pain suspected to be ischemi...
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Ronen Rubinshtein,
David A. Halon,
Tamar Gaspar,
Jorge E. Schliamser,
Nisan Yaniv,
Ronny Ammar,
Moshe Y. Flugelman,
Nathan Peled,
Basil S. Lewis
et al.
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Full-length article
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pages 925-929
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Self-Reported Use of Complementary and Alternative Medicine in Patients With Previous Acute Coronary Syndrome
Complementary and alternative medicine (CAM) use is common in patients with cardiovascular disease. Although numerous efforts have sought to understand CAM types and the prevalence of CAM, whether pat...
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Carole Decker,
Jason Huddleston,
Mikhail Kosiborod,
Donna M. Buchanan,
Casey Stoner,
Angela Jones,
Sudeshna Banerjee,
John A. Spertus
et al.
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Full-length article
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pages 930-933
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Usefulness of ST Depression With T-Wave Inversion in Leads V4 to V6 for Predicting One-Year Mortality in Non–ST-Elevation Acute Coronary Syndrome (from the Electrocardiographic Analysis of the Global Use of Strategies to Open Occluded Coronary Arteries IIB Trial)
ST-segment depression (ST-D) on the admission electrocardiogram of patients with non–ST-elevation acute coronary syndromes (NSTEACSs) is associated with higher mortality. However, few studies have eva...
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Shaul Atar,
Yuling Fu,
Galen S. Wagner,
Salvatore Rosanio,
Alejandro Barbagelata,
Yochai Birnbaum
et al.
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Full-length article
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pages 934-938
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Prognostic Value of Transient and Sustained Increase in In-Hospital Creatinine on Outcomes of Patients Admitted With Acute Coronary Syndrome
A history of renal insufficiency or increased creatinine level on admission is associated with poor outcomes in patients with acute coronary syndrome (ACS). This study sought to determine whether in-h...
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Rakesh Latchamsetty,
Jianming Fang,
Eva Kline-Rogers,
Debabrata Mukherjee,
Richard F. Otten,
Troy M. LaBounty,
Michael S. Emery,
Kim A. Eagle,
James B. Froehlich
et al.
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Short communication
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pages 939-942
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| Roundtable Discussion (CME) |
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The Editor’s Roundtable: Intravascular Ultrasonic Imaging of the Coronary Arteries
This CME activity is supported by an educational grant from Pfizer, Inc., New York, New York.
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Vincent E. Friedewald,
Steven P. Marso,
E. Murat Tuzcu,
Neil J. Weissman,
William C. Roberts
et al.
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Discussion
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pages 943-950
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| Preventive Cardiology |
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Author(s) |
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Value of Electrocardiographic and Ankle–Brachial Index Abnormalities for Prediction of Coronary Atherosclerosis in Asymptomatic Subjects With Type 2 Diabetes Mellitus
Type 2 diabetes mellitus (DM) is associated with increased cardiovascular risk, in part due to accelerated subclinical atherosclerosis. Electrocardiographic (ECG) and ankle–brachial index (ABI) abnorm...
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Roshanak Bagheri,
Mark Schutta,
Reshmaal Gomes Cumaranatunge,
Megan L. Wolfe,
Karen Terembula,
Barry Hoffman,
Stan Schwartz,
Stephen E. Kimmel,
Samira Farouk,
Nayyar Iqbal,
Muredach P. Reilly
et al.
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Full-length article
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pages 951-955
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| Systemic Hypertension |
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Effect of Antihypertensive Therapy on Progression of Carotid Intima-Media Thickness in Patients With Type 2 Diabetes Mellitus
Antihypertensive therapy reduces the incidence of cardiovascular events in people with diabetes mellitus (DM). However, the effects of treatment on subclinical atherosclerosis are less well studied. R...
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Ling Zheng,
Howard N. Hodis,
Thomas A. Buchanan,
Yanjie Li,
Wendy J. Mack
et al.
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Full-length article
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pages 956-960
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| Heart Failure |
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Usefulness of Right Ventricular Tissue Doppler Imaging to Predict Outcome in Left Ventricular Heart Failure Independent of Left Ventricular Diastolic Function
It is unknown whether right ventricular (RV) tissue Doppler (TD) predicts outcome in patients with left ventricular (LV) heart failure (HF) independently of contemporary echocardiographic Doppler vari...
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Hisham Dokainish,
Ranjita Sengupta,
Rajnikant Patel,
Nasser Lakkis
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Full-length article
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pages 961-965
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Qualitative Observation of Left Ventricular Multiphasic Septal Motion and Septal-to-Lateral Apical Shuffle Predicts Left Ventricular Reverse Remodeling After Cardiac Resynchronization Therapy
A multiphasic septal motion and typical septal-to-lateral apical shuffle of the left ventricle can be observed echocardiographically in some patients with left branch bundle block. The relation of bot...
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Annemieke H.M. Jansen,
Jan melle van Dantzig,
Franck Bracke,
Albert Meijer,
Kathinka H. Peels,
Renee B.A. van den Brink,
Emile C. Cheriex,
Ben J.M. Delemarre,
Pol A. van der Wouw,
Hendrikus H.M. Korsten,
Norbert M. van Hemel
et al.
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Full-length article
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pages 966-969
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| Valvular Heart Disease |
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Design and Baseline Characteristics of the Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) Study
Aortic valve stenosis and atherosclerotic disease have several risk factors in common, in particular, hypercholesterolemia. Histologically, the diseased valves appear to have areas of inflammation muc...
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Anne B. Rossebø,
Terje R. Pedersen,
Christopher Allen,
Kurt Boman,
John Chambers,
Kenneth Egstrup,
Eva Gerdts,
Christa Gohlke-Bärwolf,
Ingar Holme,
V. Antero Y. Kesäniemi,
William Malbecq,
Christoph Nienaber,
Simon Ray,
Terje Skjærpe,
Kristian Wachtell,
Ronnie Willenheimer
et al.
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Full-length article
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pages 970-973
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| Cardiomyopathy |
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Acute Cardiac Functional and Morphological Changes After Anthracycline Infusions in Children
The aim of this study was to describe the acute effects of anthracyclines on left ventricular systolic and diastolic function using different echocardiographic modalities. Thirteen children scheduled ...
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Javier Ganame,
Piet Claus,
Benedicte Eyskens,
Anne Uyttebroeck,
Marleen Renard,
Jan D’hooge,
Marc Gewillig,
Bart Bijnens,
George R. Sutherland,
Luc Mertens
et al.
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Full-length article
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pages 974-977
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| Congenital Heart Disease |
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Progressive Dilation of the Ascending Aorta in Children With Isolated Bicuspid Aortic Valve
Although patients with bicuspid aortic valves (BAVs) are predisposed to ascending aortic (AA) dilation, stenosis, and dissection, the development of aortic disease in children with BAVs is poorly desc...
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Kathryn W. Holmes,
Christoph U. Lehmann,
Darshan Dalal,
Khuram Nasir,
Harry C. Dietz,
William J. Ravekes,
W. Reid Thompson,
Philip J. Spevak
et al.
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Full-length article
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pages 978-983
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Transcatheter Closure of Perimembranous Ventricular Septal Defects in Infants and Children Using the Amplatzer Perimembranous Ventricular Septal Defect Occluder
There are very few published reports of the transcatheter closure of perimembranous ventricular septal defects (PMVSDs) using the Amplatzer PMVSD occluder with encouraging initial results. This report...
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Basil (Vasilios) D. Thanopoulos,
Michael L. Rigby,
Evangelos Karanasios,
Christodoulos Stefanadis,
Nico Blom,
Jaap Ottenkamp,
Armine Zarayelyan
et al.
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Full-length article
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pages 984-989
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| Miscellaneous |
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Frequency and Extent of Media in the Internal Carotid Artery in “Endarterectomy” Specimens
Carotid endarterectomy has been performed now for approximately 50 years. No report, however, has described the presence of media in these “endarterectomy” specimens. From January 1997 through May 200...
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William Clifford Roberts,
Nolan Joseph Laborde,
Gregory John Pearl
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Short communication
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pages 990-992
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Assessment of Fetal Myocardial Performance Using Myocardial Deformation Analysis
Conventional techniques for the assessment of cardiac function on the basis of M-mode or 2-dimensional modalities are technically difficult, load dependent, and provide information on global ventricul...
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Zeev Perles,
Amiram Nir,
Sagui Gavri,
Azaria J.J.T. Rein
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Short communication
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pages 993-996
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Usefulness of an Abnormal Cardiovascular Response During Low-Grade Head-Up Tilt-Test for Discriminating Adolescents With Chronic Fatigue from Healthy Controls
Hemodynamic dysfunction is documented in chronic fatigue syndrome (CFS). This study was conducted to investigate cardiovascular responses to orthostatic stress in adolescents with CFS, using a novel p...
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Vegard Bruun Wyller,
Reidar Due,
J. Philip Saul,
Jan P. Amlie,
Erik Thaulow
et al.
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Full-length article
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pages 997-1001
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Impact of Smart Infusion Technology on Administration of Anticoagulants (Unfractionated Heparin, Argatroban, Lepirudin, and Bivalirudin)
This study reviewed 863 alerts generated from the infusion of anticoagulants in 355 patients from October 2003 to January 2005. Alerts were generated by smart infusion technology pumps and recorded in...
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John Fanikos,
Karen Fiumara,
Steve Baroletti,
Carol Luppi,
Catherine Saniuk,
Amar Mehta,
Jon Silverman,
Samuel Z. Goldhaber
et al.
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Short communication
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pages 1002-1005
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| Review |
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Effect of Inhibition of the Renin-Angiotensin System on Development of Type 2 Diabetes Mellitus (Meta-Analysis of Randomized Trials)
The increasing prevalence and costs of type 2 diabetes mellitus (DM) make strategies to prevent its development vitally important. This analysis was conducted to determine if angiotensin-converting en...
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Richard Andraws,
David L. Brown
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Review article
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pages 1006-1012
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| Editorials |
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The Things to Come of SHAPE: Cost and Effectiveness of Cardiovascular Prevention
It has been proposed recently that asymptomatic adults undergo routine screening for subclinical atherosclerosis using electron-beam computed tomography or carotid ultrasound as the basis for the phar...
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George A. Diamond,
Sanjay Kaul
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Discussion
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pages 1013-1015
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Assessing Prognosis in Patients With Diabetes Mellitus—The Achilles’ Heel of Cardiac Stress Imaging Tests?
The prognostic utility of stress imaging studies has been validated in numerous studies and, in general, patients with a normal imaging study have annual cardiac ischemic event rates of <1%. Howeve...
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Masoor Kamalesh,
Harvey Feigenbaum,
Stephen Sawada
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Discussion
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pages 1016-1019
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Late Stent Thrombosis: Problem or Not?
Late stent thrombosis (LST) and very late stent thrombosis (VLST) of >1 year have been reported to occur at an unexpected rate in patients with drug-eluting stents (DESs). Meta-analyses of previous...
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John Somberg,
Judah Weinberger
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Discussion
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pages 1020-1023
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| Readers' Comments |
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The Triangle of Valve Calcification–Cytokine–Bone Resorption: Propose of Novel Potential Pathophysiologic Link
We read with great interest the report by Atalar et al in a recent issue. In their study, they assessed the role of osteopontin in patients with rheumatic valve disease with respect to valve calcifica...
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Vedat Davutoglu,
Ibrahim Sari
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Correspondence
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page 1024
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Predictors of Left Ventricular Remodeling After Reperfused Acute Myocardial Infarction
05 February 2007
Recently, Savoye et al reported on the incidence of and risk factors for left ventricular (LV) remodeling complicating acute myocardial infarction (AMI). They postulated that despite modern therapeuti...
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Christodoulos E. Papadopoulos,
Haralambos I. Karvounis,
Georgios Giannakoulas,
Theodoros D. Karamitsos,
Georgios K. Efthimiadis,
Georgios E. Parharidis
et al.
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Correspondence
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pages 1024-1025
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Selective Serotonin Reuptake Inhibitors May Interfere With the Antiplatelet Effect of Clopidogrel
We read the report by Xiong et al with great interest. The investigators prospectively examined collected data in the Duke Databank for Cardiovascular Disease from January 1, 1999, to December 31, 200...
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Antal Tibold,
Gergely Feher,
Andras Csejtei,
Antal Tettinger,
Istvan Kiss
et al.
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Correspondence
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pages 1025-1026
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| Frontmatter |
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Editorial Board
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Editorial board
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page A1
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Contents
Inflammatory Markers, Angiographic Severity of Coronary Artery Disease, and Patient Outcome 879
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Contents list
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pages A3-A5
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