| Coronary Artery Disease |
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Comparison of Role of Early (Less Than Six Hours) to Later (More Than Six Hours) or No Cardiac Catheterization After Resuscitation From Out-of-Hospital Cardiac Arrest
21 November 2011
Despite reports of patients with resuscitated sudden cardiac arrest (rSCA) receiving acute cardiac catheterization, the efficacy of this strategy is largely unknown. We hypothesized that acute cardiac...
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Justin A. Strote,
Charles Maynard,
Michele Olsufka,
Graham Nichol,
Michael K. Copass,
Leonard A. Cobb,
Francis Kim
et al.
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451-454
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Usefulness of Minimum Stent Cross Sectional Area as a Predictor of Angiographic Restenosis After Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction (from the HORIZONS-AMI Trial IVUS Substudy)
28 November 2011
HORIZONS-AMI was a prospective dual-arm randomized trial of different antithrombotic regimens and stent types in patients with ST-segment elevation myocardial infarction. A formal intravascular ultras...
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So-Yeon Choi,
Akiko Maehara,
Ecaterina Cristea,
Bernhard Witzenbichler,
Giulio Guagliumi,
Bruce Brodie,
Mirle A. Kellett,
Ovidiu Dressler,
Alexandra J. Lansky,
Helen Parise,
Roxana Mehran,
Gary S. Mintz,
Gregg W. Stone
et al.
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455-460
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Risk Factors and Effects on Long-Term Outcomes of Cardiac Troponin I Elevation After Drug-Eluting Stent Implantation in Patients With Stable Coronary Artery Disease
02 December 2011
This study evaluated the risk factors of postprocedure cardiac troponin I (cTnI) increase and its effects on repeat revascularization and on overall clinical outcomes in patients with angina and norma...
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Jin-Sin Koh,
Jae-Hong Park,
Dong-Ho Shin,
Tae-Jin Youn,
Il-Young Oh,
Chang-Hwan Yoon,
Jung-Won Suh,
Young-Seok Cho,
Goo-Yeong Cho,
In-Ho Chae,
Dong-Ju Choi
et al.
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461-465
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Outcomes of Drug-Eluting Stents for Protected Left Main Coronary Artery Disease (from the Multicenter, United States DEScover Registry)
28 November 2011
Percutaneous coronary intervention (PCI) for protected left main coronary artery (PLM) disease is complex because of patient and lesion factors; however, limited data exist on the outcomes of drug-elu...
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Joshua Leitner,
Helen A. Vlachos,
Faith Selzer,
Sameer M. Jamal,
Kevin E. Kip,
David O. Williams,
J. Dawn Abbott
et al.
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466-470
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Impact of Periprocedural Atrial Fibrillation on Short-Term Clinical Outcomes Following Percutaneous Coronary Intervention
19 December 2011
There are few data on the incidence and clinical outcomes of patients with atrial fibrillation (AF) treated in the era of percutaneous coronary intervention (PCI). We analyzed 30-day clinical outcomes...
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William Chan,
Andrew E. Ajani,
David J. Clark,
Dion Stub,
Nick Andrianopoulos,
Angela L. Brennan,
Gishel New,
Martin Sebastian,
Rozanne Johnston,
Antony Walton,
Christopher M. Reid,
Anthony M. Dart,
Stephen J. Duffy,
Melbourne Interventional Group Investigators
et al.
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471-477
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Usefulness of Transient and Persistent No Reflow to Predict Adverse Clinical Outcomes Following Percutaneous Coronary Intervention
19 December 2011
The no reflow phenomenon is reported to occur in >2% of all percutaneous coronary interventions (PCIs) and portends a poor prognosis. We analyzed data from 5,286 consecutive patients who underwent ...
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William Chan,
Dion Stub,
David J. Clark,
Andrew E. Ajani,
Nick Andrianopoulos,
Angela L. Brennan,
Gishel New,
Alexander Black,
James A. Shaw,
Christopher M. Reid,
Anthony M. Dart,
Stephen J. Duffy,
Melbourne Interventional Group Investigators
et al.
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478-485
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Prognostic Value of Uric Acid in Patients With ST-Elevated Myocardial Infarction Undergoing Primary Coronary Intervention
21 November 2011
Elevated uric acid (UA) levels have been associated with cardiovascular disease in epidemiologic studies. The relation between UA levels and long-term outcomes in patients with ST-segment elevation my...
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Mehmet G. Kaya,
Huseyin Uyarel,
Mahmut Akpek,
Nihat Kalay,
Mehmet Ergelen,
Erkan Ayhan,
Turgay Isik,
Gokhan Cicek,
Deniz Elcik,
Ömer Sahin,
Said M. Cosgun,
Abdurrahman Oguzhan,
Mehmet Eren,
C. Michael Gibson
et al.
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486-491
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Usefulness of Adiponectin as a Predictor of All Cause Mortality in Patients With ST-Segment Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention
21 November 2011
Substantial evidence points to a protective role of adiponectin against atherosclerosis and cardiovascular (CV) disease. However, in the setting of an acute myocardial infarction (AMI), the role of ad...
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Søren Lindberg,
Sune H. Pedersen,
Rasmus Møgelvang,
Mette Bjerre,
Jan Frystyk,
Allan Flyvbjerg,
Søren Galatius,
Jan Skov Jensen
et al.
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492-496
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Comparison of Clinical Characteristics, Treatments and Outcomes of Patients With ST-Elevation Acute Myocardial Infarction With Versus Without New or Presumed New Left Bundle Branch Block (from NCDR®)
07 December 2011
Guidelines recommend urgent reperfusion for patients with new left bundle branch block (LBBB), similar to patients with ST-segment elevation myocardial infarction (STEMI). However, there are limited c...
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Khung Keong Yeo,
Shuang Li,
Ezra A. Amsterdam,
Tracy Y. Wang,
Deepak L. Bhatt,
Jorge F. Saucedo,
Michael C. Kontos,
Matthew T. Roe,
William J. French
et al.
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497-501
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Effect of Hurricane Katrina on Incidence of Acute Myocardial Infarction in New Orleans Three Years After the Storm
08 December 2011
To detect a long-term increase in the incidence of acute myocardial infarction (AMI) after Hurricane Katrina and to investigate the pertinent contributing factors, we conducted a single-center retrosp...
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Zhen Jiao,
Socrates V. Kakoulides,
John Moscona,
Jabar Whittier,
Sudesh Srivastav,
Patrice Delafontaine,
Anand Irimpen
et al.
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502-505
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Effect of Anemia on Short- and Long-Term Outcome in Patients Hospitalized for Acute Coronary Syndromes
07 December 2011
Anemia is common in hospitalized cardiac patients and is associated with adverse outcomes. The aim of this study was to identify the association of anemia with early and long-term outcomes in patients...
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John O. Younge,
Sjoerd T. Nauta,
K. Martijn Akkerhuis,
Jaap W. Deckers,
Ron T. van Domburg
et al.
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506-510
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Comparison of Coronary Calcium in Firefighters With Abnormal Stress Test Findings and in Asymptomatic Nonfirefighters With Abnormal Stress Test Findings
21 November 2011
Firefighters are known to have an elevated rate of sudden cardiac death compared to the general population. It is unclear whether this finding is related to underlying cardiovascular risk factors or w...
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Priya Pillutla,
Dong Li,
Naser Ahmadi,
Matthew J. Budoff
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511-514
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Comparison of Osteoprotegerin to Traditional Atherosclerotic Risk Factors and High-Sensitivity C-Reactive Protein for Diagnosis of Atherosclerosis
21 November 2011
Atherosclerosis is the main cause of cardiovascular disease, but the extent of atherosclerosis in individual patients is difficult to estimate. A biomarker of the atherosclerotic burden would be very ...
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Rasmus Mogelvang,
Sune H. Pedersen,
Allan Flyvbjerg,
Mette Bjerre,
Allan Z. Iversen,
Soren Galatius,
Jan Frystyk,
Jan S. Jensen
et al.
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515-520
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| Preventive Cardiology |
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Cardiovascular Disease and Risk in Primary Care Settings in the United States
24 November 2011
Primary care site may play an important role in cardiovascular disease prevalence; however, the distribution of risk factors and outcomes across care sites is not known. In this study, a cross-section...
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Chima D. Ndumele,
Heather J. Baer,
Shimon Shaykevich,
Stuart R. Lipsitz,
Leroi S. Hicks
et al.
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521-526
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High-Density Lipoprotein Cholesterol Efflux, Nitration of Apolipoprotein A-I, and Endothelial Function in Obese Women
21 November 2011
Subjects at risk of atherosclerosis might have dysfunctional high-density lipoprotein (HDL) despite normal cholesterol content in the plasma. We considered whether the efflux of excess cellular choles...
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Edward Vazquez,
Amar A. Sethi,
Lita Freeman,
Gloria Zalos,
Hira Chaudhry,
Erin Haser,
Brittany O. Aicher,
Angel Aponte,
Marjan Gucek,
Gregory J. Kato,
Myron A. Waclawiw,
Alan T. Remaley,
Richard O. Cannon
et al.
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527-532
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| Arrhythmias and Conduction Disturbances |
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White Blood Cell Count and Risk of Incident Atrial Fibrillation (From the Framingham Heart Study)
21 November 2011
Several studies have reported that inflammatory markers are associated with atrial fibrillation (AF). The white blood cell (WBC) count is a widely available and broadly used marker of systemic inflamm...
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Michiel Rienstra,
Jenny X. Sun,
Jared W. Magnani,
Moritz F. Sinner,
Steven A. Lubitz,
Lisa M. Sullivan,
Patrick T. Ellinor,
Emelia J. Benjamin
et al.
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533-537
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Relation of Renal Function to Risk for Incident Atrial Fibrillation in Women
21 November 2011
Few prospective studies have explored the association between renal function and risk for incident atrial fibrillation (AF) in apparently healthy populations. A total of 24,746 women participating in ...
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Roopinder K. Sandhu,
Tobias Kurth,
David Conen,
Nancy R. Cook,
Paul M. Ridker,
Christine M. Albert
et al.
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538-542
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Rates and Implications for Hospitalization of Patients ≥65 Years of Age With Atrial Fibrillation/Flutter
28 November 2011
The responsibility of managing atrial fibrillation (AF) and atrial flutter (AFL) falls predominantly on the Medicare system. Patients with AF or AFL often have a range of cardiovascular (CV) co-morbid...
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Gerald V. Naccarelli,
Stephen S. Johnston,
Mehul Dalal,
Jay Lin,
Parag P. Patel
et al.
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543-549
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Usefulness of Transesophageal Echocardiography to Confirm Clinical Utility of CHA2DS2-VASc and CHADS2 Scores in Atrial Flutter
02 December 2011
The CHA2DS2-VASc and CHADS2 risk stratification schemes are used to predict thromboembolism and ischemic stroke in patients with atrial fibrillation. However, limited data are available regarding the ...
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Milind G. Parikh,
Zaid Aziz,
Kousik Krishnan,
Christopher Madias,
Richard G. Trohman
et al.
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550-555
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Ventricular Dyssynchrony of Idiopathic Versus Pacing-Induced Left Bundle Branch Block and Its Prognostic Effect in Patients With Preserved Left Ventricular Systolic Function
02 December 2011
The extent of left ventricular (LV) dyssynchrony might not be comparable between right ventricular pacing-induced left bundle branch block (RV-LBBB) and idiopathic LBBB (iLBBB), despite the morphologi...
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Hyo Eun Park,
Ji-Hyun Kim,
Hyung-Kwan Kim,
Seung-Pyo Lee,
Eue-Keun Choi,
Yong-Jin Kim,
Seil Oh,
Goo-Yeong Cho,
Dae-Won Sohn
et al.
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556-562
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| Roundtable Discussion |
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The Editor's Roundtable: Medical Management of Atrial Fibrillation
This article is supported by an educational grant from sanofi-aventis U.S., Bridgewater, New Jersey.
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Vincent E. Friedewald,
Robert C. Kowal,
Brian Olshansky,
Clyde W. Yancy,
William C. Roberts
et al.
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563-569
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| Systemic Hypertension |
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Prevalence of, and Barriers to, Preventive Lifestyle Behaviors in Hypertension (from a National Survey of Canadians With Hypertension)
12 December 2011
Patients with hypertension are advised to lower their blood pressure to <140/90 mm Hg through sustained lifestyle modification and/or pharmacotherapy. To describe the use of lifestyle changes for b...
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Marianne E. Gee,
Asako Bienek,
Norman R.C. Campbell,
Christina M. Bancej,
Cynthia Robitaille,
Janusz Kaczorowski,
Michel Joffres,
Sulan Dai,
Femida Gwadry-Sridar,
Robert P. Nolan
et al.
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570-575
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Candesartan-Based Therapy and Risk of Cancer in Patients With Systemic Hypertension (Heart Institute of Japan Candesartan Randomized Trial for Evaluation in Coronary Artery Disease [HIJ-CREATE] Substudy)
18 November 2011
The aim of the present study was to clarify the influence of candesartan-based therapy on subsequent carcinogenesis and cancer death in patients with coronary artery disease with hypertension in a sub...
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Ryo Sugiura,
Hiroshi Ogawa,
Toshiaki Oka,
Ryo Koyanagi,
Nobuhisa Hagiwara,
HIJ-CREATE Investigators
et al.
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576-580
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| Valvular Heart Disease |
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Comparison of Outcomes in Patients Having Isolated Transcatheter Aortic Valve Implantation Versus Combined With Preprocedural Percutaneous Coronary Intervention
02 December 2011
Coronary artery disease negatively affects the outcome of patients undergoing surgical aortic valve replacement and practice guidelines recommend revascularization at time of surgery. In patients unde...
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Mohamed Abdel-Wahab,
Ahmad E. Mostafa,
Volker Geist,
Björn Stöcker,
Ken Gordian,
Constanze Merten,
Doreen Richardt,
Ralph Toelg,
Gert Richardt
et al.
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581-586
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| Methods |
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Value of Electrocardiogram in the Differentiation of Hypertensive Heart Disease, Hypertrophic Cardiomyopathy, Aortic Stenosis, Amyloidosis, and Fabry Disease
21 November 2011
Left ventricular hypertrophy is 1 of the most frequent cardiac manifestations associated with an unfavorable prognosis. However, many different causes of left ventricular hypertrophy exist. The aim of...
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Mehdi Namdar,
Jan Steffel,
Sandra Jetzer,
Christian Schmied,
David Hürlimann,
Giovanni G. Camici,
Fatih Bayrak,
Danilo Ricciardi,
Jayakeerthi Y. Rao,
Carlo de Asmundis,
Gian-Battista Chierchia,
Andrea Sarkozy,
Thomas F. Lüscher,
Rolf Jenni,
Firat Duru,
Pedro Brugada
et al.
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587-593
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Accuracy of Estimating Resting Oxygen Uptake and Implications for Hemodynamic Assessment
21 November 2011
The Fick principle (cardiac output [Qc] = oxygen uptake [Vo2]/arteriovenous oxygen difference) can be used to calculate Qc, with VO2 frequently estimated by derived equations. To compare the accuracy ...
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Nikhil Narang,
M. Odette Gore,
Peter G. Snell,
Colby R. Ayers,
Santiago Lorenzo,
Graeme Carrick-Ranson,
Tony G. Babb,
Benjamin D. Levine,
Amit Khera,
James A. de Lemos,
Darren K. McGuire
et al.
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594-598
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| Readers' Comments |
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Electrocardiogram in Left Ventricular Hypertrabeculation/Noncompaction
The report by Stöllberger et al in the October 1, 2011, issue of The American Journal of Cardiology on the frequency of stroke and embolism in 144 patients with left ventricular hypertrabeculation/non...
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John E. Madias
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599
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Authors' Reply
Left ventricular hypertrabeculation/noncompaction (LVHT/NC) is characterized by trabeculations in the inner core of myocardium and a thinner than usual external compact myocardial core. Dr. Madias ass...
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Claudia Stöllberger,
Daniel Gerger,
Christian Wegner,
Josef Finsterer
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599
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Conquering Atherosclerosis Starts With Improving Medical Education
The United States Department of Health and Human Services recently launched the Million Hearts initiative to prevent 1 million heart attacks and strokes over the next 5 years by implementing proved, e...
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Michael A. Kadoch
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599-600
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Long-Term Mortality and Role of Troponin Elevation in Hypertensive Emergencies
We read with great interest the report “Effect of Joint National Committee VII Report on Hospitalizations for Hypertensive Emergencies in the United States” by Deshmukh et al. The investigators provid...
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Apurva Badheka,
Maithili Shenoy,
Ankit Rathod,
Tushar Tuliani,
Luis Afonso
et al.
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600
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| Frontmatter |
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Editorial Board
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A7
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Contents
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A15
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