American Journal of Cardiology
Volume 79, Issue 4 , Pages 529-531 , 15 February 1997

Effect of Acute Cigarette Smoking on Endothelium-Dependent Brachial Artery Dilatation in Healthy Individuals

  • John Lekakis, MD

      Affiliations

    • Department of Clinical Therapeutics, Alexandra University Hospital, Athens, Greece
    • Corresponding Author InformationDr. Lekakis, 86 Alkionis Street, P. Faliron, 17562, Athens, Greece.
    • ,
  • Christos Papamichael, MD

      Affiliations

    • Department of Clinical Therapeutics, Alexandra University Hospital, Athens, Greece
    • ,
  • Costas Vemmos, MD

      Affiliations

    • Department of Clinical Therapeutics, Alexandra University Hospital, Athens, Greece
    • ,
  • John Nanas, MD

      Affiliations

    • Department of Clinical Therapeutics, Alexandra University Hospital, Athens, Greece
    • ,
  • Dimitrios Kontoyannis, MD

      Affiliations

    • Department of Clinical Therapeutics, Alexandra University Hospital, Athens, Greece
    • ,
  • Stamatios Stamatelopoulos, MD

      Affiliations

    • Department of Clinical Therapeutics, Alexandra University Hospital, Athens, Greece
    • ,
  • Spyridon Moulopoulos, MD

      Affiliations

    • Department of Clinical Therapeutics, Alexandra University Hospital, Athens, Greece

Received 1 July 1996 ,Accepted 25 September 1996.

References 

  1. Celermajer DS, Sorensen KE, Georgakopoulos D, Bull C, Thomas O, Robinson J, et al. Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilatation in healthy young adults. Circulation. 1993;88(part 1):2149–2155
  2. Celermajer DS, Adams MR, Clarkson P, Robinson J, McCredie R, Donald A, et al. Passive smoking and impaired endothelium-dependent arterial dilatation in healthy young adults. N Engl J Med. 1996;334:150–154
  3. Caralis DG, Deligonul U, Kern MJ, Cohen JD. Smoking is a risk factor for coronary spasm in young women. Circulation. 1992;85:905–909
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  9. Celermajer DS, Sorensen KE, Gooch VM, Spiegelhalter DJ, Miller OI, Sullivan ID, et al. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet. 1992;340:1111–1115
  10. Katz SD, Biasucci L, Sabba C, Storm JA, Jondeau G, Galvao M, Solomon S, Nicolic SD, Forman R, Lejemtel TH. Impaired endothelium-mediated vasodilatation in the peripheral vasculature of patients with congestive heart failure. J Am Coll Cardiol 1992;19:981–925.
  11. Zeiher AM, Drexler H, Wollschlager H, Just H. Modulation of coronary vasomotor tone in humans: progressive endothelial dysfunction with different early stages of coronary atherosclerosis. Circulation. 1991;83:391–401
  12. Nicod P, Rehr R, Winniford MD, Campbell WB, Firth BG, Hillis LD. Acute systemic and coronary hemodynamic and serologic responses to cigarette smoking in long-term smokers with atherosclerotic coronary artery disease. J Am Coll Cardiol. 1984;4:964–971
  13. Schöning M, Walter J, Scheel P. Estimation of cerebral blood flow through color duplex sonography of the carotid and vertebral arteries in healthy adults. Stroke. 1994;25:17–22
  14. Antony I, Lerebours G, Nitenber A. Loss of flow-dependent coronary artery dilatation in patients with hypertension. Circulation. 1995;91:1624–1628
  15. Sorensen KE, Celermajer DS, Georgakopoulos D, Hatcher G, Betteridge DJ, Deanfield JE. Impairment of endothelium-dependent dilatation is an early event and is related to the lipoprotein (a) level. J Clin Invest. 1994;93:50–55
  16. Johnstone MT, Creager SJ, Scales KM, Cusco JA, Lee BK, Creager MA. Impaired endothelium-dependent vasodilatation in patients with insulin-dependent diabetes mellitus. Circulation. 1993;88:2510–2516
  17. Benowitz NL. Pharmacologic aspects of cigarette smoking and nicotine addiction. N Engl J Med. 1988;319:1318–1330

PII: S0002-9149(96)00805-3

American Journal of Cardiology
Volume 79, Issue 4 , Pages 529-531 , 15 February 1997

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