American Journal of Cardiology
Volume 106, Issue 4 , Pages 587-592 , 15 August 2010

Can a Statin Neutralize the Cardiovascular Risk of Unhealthy Dietary Choices?

Received 23 December 2009 ,Revised 30 March 2010 ,Accepted 30 March 2010.

  • Image Result

    Logarithm of the relative risk (RR) for fatal coronary artery disease (CAD) and nonfatal myocardial infarction (MI) associated with (A) daily total fat intake and (B) daily trans fat intake.

    Logarithm of the relative risk (RR) for fatal coronary artery disease (CAD) and nonfatal myocardial infarction (MI) associated with (A) daily total fat intake and (B) daily trans fat intake.

  • Image Result

    Relative risk (RR) for event versus reduction in low-density lipoprotein cholesterol (LDL-c) with various doses of different statins. MI = myocardial infarction; IHD = ischaemic heart disease.

    Relative risk (RR) for event versus reduction in low-density lipoprotein cholesterol (LDL-c) with various doses of different statins. MI = myocardial infarction; IHD = ischaemic heart disease.

  • Image Result

    Juxtaposition of “good” and “bad” RRs for coronary artery disease (logarithmic scale). Black circle indicates pooled estimate. (A) Total fat, (B) trans fat. Abbreviations as in Table 1.

    Juxtaposition of “good” and “bad” RRs for coronary artery disease (logarithmic scale). Black circle indicates pooled estimate. (A) Total fat, (B) trans fat. Abbreviations as in Table 1.

  • Image Result

    New concept in fast food risk reduction.

    New concept in fast food risk reduction.

 Dr. Francis is supported by grant FS 04/079 from the British Heart Foundation, London, United Kingdom.

 We have chosen the Quarter Pounder® because it is a product that is universally known and universally uniform in its characteristics. We use it, however, solely as a proxy for all foods of certain fat and trans-fat content. We do not suggest that a Quarter Pounder® poses any health threat greater than any other food with the same fat and trans-fat content.

PII: S0002-9149(10)00870-2

doi: 10.1016/j.amjcard.2010.03.077

American Journal of Cardiology
Volume 106, Issue 4 , Pages 587-592 , 15 August 2010