American Journal of Cardiology
Volume 105, Issue 10 , Pages 1371-1377.e1, 15 May 2010

Interleukin-1 Blockade With Anakinra to Prevent Adverse Cardiac Remodeling After Acute Myocardial Infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot Study)

  • Antonio Abbate, MD, PhD

      Affiliations

    • Virginia Commonwealth University, VCU Pauley Heart Center, Richmond, Virginia
    • Corresponding Author InformationCorresponding author: Tel: (804) 828 0513; fax: (360) 323-1204
  • ,
  • Michael C. Kontos, MD

      Affiliations

    • Virginia Commonwealth University, VCU Pauley Heart Center, Richmond, Virginia
  • ,
  • John D. Grizzard, MD

      Affiliations

    • Virginia Commonwealth University, VCU Pauley Heart Center, Richmond, Virginia
  • ,
  • Giuseppe G.L. Biondi-Zoccai, MD

      Affiliations

    • Division of Cardiology, University of Turin, Turin, Italy
  • ,
  • Benjamin W. Van Tassell, PharmD

      Affiliations

    • Virginia Commonwealth University, VCU Pauley Heart Center, Richmond, Virginia
  • ,
  • Roshanak Robati, MD

      Affiliations

    • Virginia Commonwealth University, VCU Pauley Heart Center, Richmond, Virginia
  • ,
  • Lenore M. Roach, RN

      Affiliations

    • Virginia Commonwealth University, VCU Pauley Heart Center, Richmond, Virginia
  • ,
  • Ross A. Arena, PhD

      Affiliations

    • Virginia Commonwealth University, VCU Pauley Heart Center, Richmond, Virginia
  • ,
  • Charlotte S. Roberts, ACNP

      Affiliations

    • Virginia Commonwealth University, VCU Pauley Heart Center, Richmond, Virginia
  • ,
  • Amit Varma, MD

      Affiliations

    • Virginia Commonwealth University, VCU Pauley Heart Center, Richmond, Virginia
  • ,
  • Christopher C. Gelwix, MD

      Affiliations

    • Virginia Commonwealth University, VCU Pauley Heart Center, Richmond, Virginia
  • ,
  • Fadi N. Salloum, PhD

      Affiliations

    • Virginia Commonwealth University, VCU Pauley Heart Center, Richmond, Virginia
  • ,
  • Andrea Hastillo, MD

      Affiliations

    • Virginia Commonwealth University, VCU Pauley Heart Center, Richmond, Virginia
  • ,
  • Charles A. Dinarello, MD

      Affiliations

    • Department of Internal Medicine, University of Colorado, Aurora, Colorado
  • ,
  • George W. Vetrovec, MD

      Affiliations

    • Virginia Commonwealth University, VCU Pauley Heart Center, Richmond, Virginia
  • ,
  • VCU-ART Investigators (see Appendix)

Received 6 November 2009; received in revised form 22 December 2009; accepted 22 December 2009. published online 05 April 2010.

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 This study was funded by a Virginia Commonwealth University “A.D. Williams Fund” grant to Dr. Abbate and a Virginia Commonwealth University General Clinical Research Center Funds for Pilot Clinical Research to Dr. Abbate, and by the VCU Pauley Heart Center funds (Richmond, Virginia).

PII: S0002-9149(10)00066-4

doi:10.1016/j.amjcard.2009.12.059

American Journal of Cardiology
Volume 105, Issue 10 , Pages 1371-1377.e1, 15 May 2010