American Journal of Cardiology
Volume 105, Issue 8 , Pages 1107-1111, 15 April 2010

Incidence of Subclinical Atherosclerosis as a Marker of Cardiovascular Risk in Retired Professional Football Players

  • R. Todd Hurst, MD

      Affiliations

    • Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, Arizona
    • Corresponding Author InformationCorresponding author
  • ,
  • Robert F. Burke, MD

      Affiliations

    • Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, Arizona
  • ,
  • Erik Wissner, MD

      Affiliations

    • Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, Arizona
  • ,
  • Arthur Roberts, MD

      Affiliations

    • Living Heart Foundation, Little Silver, New Jersey
  • ,
  • Christopher B. Kendall, BS, RDCS

      Affiliations

    • Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, Arizona
  • ,
  • Steven J. Lester, MD

      Affiliations

    • Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, Arizona
  • ,
  • Virend Somers, MD, PhD

      Affiliations

    • Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, Arizona
  • ,
  • Martin E. Goldman, MD

      Affiliations

    • Cardiovascular Institute and Center for Cardiovascular Health, Mount Sinai Medical Center, New York, New York
  • ,
  • Qing Wu, ScD

      Affiliations

    • Division of Biostatistics, Mayo Clinic, Scottsdale, Arizona
  • ,
  • Bijoy Khandheria, MD

      Affiliations

    • Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, Arizona

Received 6 August 2009; received in revised form 3 December 2009; accepted 3 December 2009. published online 02 March 2010.

The purpose of this study was to evaluate subclinical atherosclerosis in retired professional football players. Two hundred one healthy former professional football players (mean age 50.8 years; mean body mass index 31.5 kg/m2) were screened for the prevalence of cardiovascular risk factors, metabolic syndrome, and subclinical atherosclerosis by carotid artery ultrasound and compared with a cohort of men of similar body mass index referred for the assessment of subclinical atherosclerosis by carotid ultrasound. The prevalence of carotid artery plaque in the players was not significantly different from that of the body mass index–matched patients (33.3% vs 29.3%, p = 0.45). For the 2 groups, the prevalence of carotid artery plaque was >3 times higher than that reported in general population studies of patients with the same age range, gender, and exclusions. Metabolic syndrome prevalence was higher in linemen than in nonlinemen (45.8% vs 22.5%, p = 0.001), but there was no statistical difference in plaque presence between linemen and nonlinemen (27.1% vs 35.9%, p = 0.23). In conclusion, despite their elite athletic histories, former professional football players have a similar prevalence of advanced subclinical atherosclerosis as a clinically referred population of overweight and obese men.

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PII: S0002-9149(09)02840-9

doi:10.1016/j.amjcard.2009.12.012

American Journal of Cardiology
Volume 105, Issue 8 , Pages 1107-1111, 15 April 2010