American Journal of Cardiology
Volume 105, Issue 8 , Pages 1047-1052 , 15 April 2010

Comparison of the Usefulness of N-Terminal Pro-Brain Natriuretic Peptide to Other Serum Biomarkers as an Early Predictor of ST-Segment Recovery After Primary Percutaneous Coronary Intervention

  • Niels J.W. Verouden, MD

      Affiliations

    • Department of Cardiology, Academic Medical Center, University of Amsterdam Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • Joost D.E. Haeck, MD

      Affiliations

    • Department of Cardiology, Academic Medical Center, University of Amsterdam Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • Wichert J. Kuijt, MD

      Affiliations

    • Department of Cardiology, Academic Medical Center, University of Amsterdam Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • Nan van Geloven, MSc

      Affiliations

    • Department of Cardiology, Academic Medical Center, University of Amsterdam Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • Karel T. Koch, MD, PhD

      Affiliations

    • Department of Cardiology, Academic Medical Center, University of Amsterdam Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • José P.S. Henriques, MD, PhD

      Affiliations

    • Department of Cardiology, Academic Medical Center, University of Amsterdam Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • Jan Baan, MD, PhD

      Affiliations

    • Department of Cardiology, Academic Medical Center, University of Amsterdam Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • Marije M. Vis, MD

      Affiliations

    • Department of Cardiology, Academic Medical Center, University of Amsterdam Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • Jan P. van Straalen

      Affiliations

    • Department of Clinical Chemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
  • ,
  • Johan Fischer, PhD

      Affiliations

    • Department of Clinical Chemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
  • ,
  • Jan J. Piek, MD, PhD

      Affiliations

    • Department of Cardiology, Academic Medical Center, University of Amsterdam Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • Jan G.P. Tijssen, PhD

      Affiliations

    • Department of Cardiology, Academic Medical Center, University of Amsterdam Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • Robbert J. de Winter, MD, PhD

      Affiliations

    • Department of Cardiology, Academic Medical Center, University of Amsterdam Academic Medical Center, Amsterdam, The Netherlands
    • Corresponding Author InformationCorresponding author: Tel: (31) 20-566-9111; fax: (31) 20-696-2609

Received 30 September 2009 ,Revised 1 December 2009 ,Accepted 1 December 2009.

References 

  1. Heeschen C, Hamm CW, Mitrovic V, Lantelme NH, White HD. N-terminal pro-B-type natriuretic peptide levels for dynamic risk stratification of patients with acute coronary syndromes. Circulation. 2004;110:3206–3212
  2. James SK, Lindahl B, Siegbahn A, Stridsberg M, Venge P, Armstrong P, et al. N-terminal pro-brain natriuretic peptide and other risk markers for the separate prediction of mortality and subsequent myocardial infarction in patients with unstable coronary artery disease: a Global Utilization of Strategies To Open occluded arteries (GUSTO)-IV substudy. Circulation. 2003;108:275–281
  3. Omland T, Persson A, Ng L, O'Brien R, Karlsson T, Herlitz J, et al. N-terminal pro-B-type natriuretic peptide and long-term mortality in acute coronary syndromes. Circulation. 2002;106:2913–2918
  4. Ndrepepa G, Braun S, Mehilli J, von Beckerath N, Nekolla S, Vogt W, et al. N-terminal pro-brain natriuretic peptide on admission in patients with acute myocardial infarction and correlation with scintigraphic infarct size, efficacy of reperfusion, and prognosis. Am J Cardiol. 2006;97:1151–1156
  5. Aviles RJ, Askari AT, Lindahl B, Wallentin L, Jia G, Ohman EM, et al. Troponin T levels in patients with acute coronary syndromes, with or without renal dysfunction. N Engl J Med. 2002;346:2047–2052
  6. Halkin A, Stone GW, Grines CL, Cox DA, Rutherford BD, Esente P, et al. Prognostic implications of creatine kinase elevation after primary percutaneous coronary intervention for acute myocardial infarction. J Am Coll Cardiol. 2006;47:951–961
  7. Suleiman M, Aronson D, Reisner SA, Kapeliovich MR, Markiewicz W, Levy Y, et al. Admission C-reactive protein levels and 30-day mortality in patients with acute myocardial infarction. Am J Med. 2003;115:695–701
  8. Anavekar NS, McMurray JJ, Velazquez EJ, Solomon SD, Kober L, Rouleau JL, et al. Relation between renal dysfunction and cardiovascular outcomes after myocardial infarction. N Engl J Med. 2004;351:1285–1295
  9. Thiele H, Kappl MJ, Linke A, Erbs S, Boudriot E, Lembcke A, et al. Influence of time-to-treatment, TIMI-flow grades, and ST-segment resolution on infarct size and infarct transmurality as assessed by delayed enhancement magnetic resonance imaging. Eur Heart J. 2007;28:1433–1439
  10. Buller CE, Fu Y, Mahaffey KW, Todaro TG, Adams P, Westerhout CM, et al. ST-segment recovery and outcome after primary percutaneous coronary intervention for ST-elevation myocardial infarction: insights from the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial. Circulation. 2008;118:1335–1346
  11. McLaughlin MG, Stone GW, Aymong E, Gardner G, Mehran R, Lansky AJ, et al. Prognostic utility of comparative methods for assessment of ST-segment resolution after primary angioplasty for acute myocardial infarction: the Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications (CADILLAC) trial. J Am Coll Cardiol. 2004;44:1215–1223
  12. Lorgis L, Zeller M, Dentan G, Sicard P, Jolak M, L'Huillier I, et al. High levels of N-terminal pro B-type natriuretic peptide are associated with ST resolution failure after reperfusion for acute myocardial infarction. QJM. 2007;100:211–216
  13. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16:31–41
  14. Thygesen K, Alpert JS, White HD. Universal definition of myocardial infarction. J Am Coll Cardiol. 2007;50:2173–2195
  15. Pencina MJ, D'Agostino RB, D'Agostino RB, Vasan RS. Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. Stat Med. 2008;27:157–172
  16. Bjorklund E, Jernberg T, Johanson P, Venge P, Dellborg M, Wallentin L, et al. Admission N-terminal pro-brain natriuretic peptide and its interaction with admission troponin T and ST segment resolution for early risk stratification in ST elevation myocardial infarction. Heart. 2006;92:735–740
  17. Richards AM, Nicholls MG, Yandle TG, Frampton C, Espiner EA, Turner JG, et al. Plasma N-terminal pro-brain natriuretic peptide and adrenomedullin: new neurohormonal predictors of left ventricular function and prognosis after myocardial infarction. Circulation. 1998;97:1921–1929
  18. Yasue H, Yoshimura M, Sumida H, Kikuta K, Kugiyama K, Jougasaki M, et al. Localization and mechanism of secretion of B-type natriuretic peptide in comparison with those of A-type natriuretic peptide in normal subjects and patients with heart failure. Circulation. 1994;90:195–203
  19. Feldman LJ, Coste P, Furber A, Dupouy P, Slama MS, Monassier JP, et al. Incomplete resolution of ST-segment elevation is a marker of transient microcirculatory dysfunction after stenting for acute myocardial infarction. Circulation. 2003;107:2684–2689
  20. Nijveldt R, Beek AM, Hirsch A, Stoel MG, Hofman MB, Umans VA, et al. Functional recovery after acute myocardial infarction: comparison between angiography, electrocardiography, and cardiovascular magnetic resonance measures of microvascular injury. J Am Coll Cardiol. 2008;52:181–189
  21. Goetze JP, Christoffersen C, Perko M, Arendrup H, Rehfeld JF, Kastrup J, et al. Increased cardiac BNP expression associated with myocardial ischemia. FASEB J. 2003;17:1105–1107
  22. Staat P, Rioufol G, Piot C, Cottin Y, Cung TT, L'Huillier I, et al. Postconditioning the human heart. Circulation. 2005;112:2143–2148

PII: S0002-9149(09)02830-6

doi: 10.1016/j.amjcard.2009.12.002

American Journal of Cardiology
Volume 105, Issue 8 , Pages 1047-1052 , 15 April 2010