American Journal of Cardiology
Volume 105, Issue 6 , Pages 813-818 , 15 March 2010

Comparison of Outcomes Between Zotarolimus- and Sirolimus-Eluting Stents in Patients With ST-Segment Elevation Acute Myocardial Infarction

  • Hyun Kuk Kim, MD

      Affiliations

    • Chonnam National University Hospital, Gwangju, South Korea
    • ,
  • Myung Ho Jeong, MD

      Affiliations

    • Chonnam National University Hospital, Gwangju, South Korea
    • Corresponding Author InformationCorresponding author: Tel: (82) 62-220-6243; fax: (82) 62-228-7174
    • ,
  • Young Keun Ahn, MD

      Affiliations

    • Chonnam National University Hospital, Gwangju, South Korea
    • ,
  • Jong Hyun Kim, MD

      Affiliations

    • Busan Hanseo Hospital, Busan, South Korea
    • ,
  • Shung Chull Chae, MD

      Affiliations

    • Kyungpook National University Hospital, Daegu, South Korea
    • ,
  • Young Jo Kim, MD

      Affiliations

    • Yeungnam University Hospital, Gyeongsan, South Korea
    • ,
  • Seung Ho Hur, MD

      Affiliations

    • Keimyung University Hospital, Daegu, South Korea
    • ,
  • In Whan Seong, MD

      Affiliations

    • Chungnam National University Hospital, Daejeon, South Korea
    • ,
  • Taek Jong Hong, MD

      Affiliations

    • Busan National University Hospital, Busan, South Korea
    • ,
  • Dong Hoon Choi, MD

      Affiliations

    • Yonsei University Severans Hospital, Seodaemun-gu, South Korea
    • ,
  • Myeong Chan Cho, MD

      Affiliations

    • Chungbuk National University Hospital, Cheongju-si, South Korea
    • ,
  • Chong Jin Kim, MD

      Affiliations

    • Kyung Hee University Hospital, Seoul, South Korea
    • ,
  • Ki Bae Seung, MD

      Affiliations

    • Catholic University Hospital, Seoul, South Korea
    • ,
  • Wook Sung Chung, MD

      Affiliations

    • Catholic University Hospital, Seoul, South Korea
    • ,
  • Yang Soo Jang, MD

      Affiliations

    • Yonsei University Hospital, Seoul, South Korea
    • ,
  • Seung Woon Rha, MD

      Affiliations

    • Korea University Hospital, Seoul, South Korea
    • ,
  • Jang Ho Bae, MD

      Affiliations

    • Konyang University Hospital, Daejon, South Korea
    • ,
  • Jeong Gwan Cho, MD

      Affiliations

    • Chonnam National University Hospital, Gwangju, South Korea
    • ,
  • Seung Jung Park, MD

      Affiliations

    • Ulsan University Hospital, Ulsan, South Korea
    • ,
  • Korea Acute Myocardial Infarction Registry Investigators

References 

  1. Kandzari DE, Leon MB. Overview of pharmacology and clinical trials program with the zotarolimus-eluting endeavor stent. J Interv Cardiol. 2006;19:405–413
  2. Fajadet J, Wijns W, Laarman GJ, Kuck KH, Ormiston J, Münzel T, et al. Randomized, double-blind, multicenter study of the endeavor zotarolimus-eluting phosphorylcholine-encapsulated stent for treatment of native coronary artery lesions: clinical and angiographic results of the ENDEAVOR II trial. Circulation. 2006;114:798–806
  3. Kandzari DE, Leon MB, Popma JJ, Fitzgerald PJ, O'Shaughnessy C, Ball MW, et al. Comparison of zotarolimus-eluting and sirolimus-eluting stents in patients with native coronary artery disease: a randomized controlled trial. J Am Coll Cardiol. 2006;48:2440–2447
  4. Thygesen K, Alpert JS, White HD Joint ESC/ACCF/AHA/WHF Task Force for the Redefinition of Myocardial Infarction. Universal definition of myocardial infarction. Eur Heart J. 2007;28:2525–2538
  5. Cutlip DE, Windecker S, Mehran R, Boam A, Cohen DJ, van Es GA, et al. Clinical end points in coronary stent trials: a case for standardized definitions. Circulation. 2007;115:2344–2351
  6. D'Agostino RB. Propensity scores in cardiovascular research. Circulation. 2007;115:2340–2343
  7. Truong QA, Cannon CP, Zakai NA, Rogers IS, Giugliano RP, Wiviott SD, et al. Thrombolysis In Myocardial Infarction (TIMI) risk index predicts long-term mortality and heart failure in patients with ST-elevation myocardial infarction in the TIMI 2 clinical trial. Am Heart J. 2009;157:673–679
  8. De Luca G, van't Hof AW, de Boer MJ, Hoorntje JC, Gosselink AT, Dambrink JH, et al. Impaired myocardial perfusion is a major explanation of the poor outcome observed in patients undergoing primary angioplasty for ST-segment-elevation myocardial infarction and signs of heart failure. Circulation. 2004;109:958–961
  9. Shlipak MG, Heidenreich PA, Noguchi H, Chertow GM, Browner WS, McClellan MB. Association of renal insufficiency with treatment and outcomes after myocardial infarction in elderly patients. Ann Intern Med. 2002;137:555–562
  10. Mehta RH, Leon MB, Sketch MH ENDEAVOR II Continued Access Registry. The relation between clinical features, angiographic findings, and the target lesion revascularization rate in patients receiving the endeavor zotarolimus-eluting stent for treatment of native coronary artery disease: an analysis of ENDEAVOR I, ENDEAVOR II, ENDEAVOR II Continued Access Registry, and ENDEAVOR III. Am J Cardiol. 2007;100:62M–70M
  11. De Luca G, Suryapranata H, Stone GW, Antoniucci D, Tcheng JE, Neumann FJ, et al. Abciximab as adjunctive therapy to reperfusion in acute ST-segment elevation myocardial infarction: a meta-analysis of randomized trials. JAMA. 2005;293:1759–1765
  12. Chevalier B, Di Mario C, Neumann FJ, Ribichini F, Urban P, Popma JJ, et al. A randomized, controlled, multicenter trial to evaluate the safety and efficacy of zotarolimus-versus paclitaxel-eluting stents in de novo occlusive lesions in coronary arteries the ZoMaxx I trial. JACC Cardiovasc Interv. 2008;1:524–532
  13. Buonamici P, Marcucci R, Migliorini A, Gensini GF, Santini A, Paniccia R, et al. Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis. J Am Coll Cardiol. 2007;49:2312–2317

PII: S0002-9149(09)02679-4

doi: 10.1016/j.amjcard.2009.11.009

American Journal of Cardiology
Volume 105, Issue 6 , Pages 813-818 , 15 March 2010

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