American Journal of Cardiology
Volume 105, Issue 5 , Pages 656-663, 1 March 2010

Safety and Efficacy of Ezetimibe Added to Atorvastatin Versus Up Titration of Atorvastatin to 40 mg in Patients ≥65 Years of Age (from the ZETia in the ELDerly [ZETELD] Study)

  • Franklin Zieve, MD, PhD

      Affiliations

    • McGuire Veterans Affairs Medical Center, Richmond, Virginia
    • Corresponding Author InformationCorresponding author: Tel: (804) 675-5151; fax: (804) 675-5139
  • ,
  • Nanette K. Wenger, MD

      Affiliations

    • Emory University School of Medicine, Atlanta, Georgia
  • ,
  • Ori Ben-Yehuda, MD

      Affiliations

    • University of California San Diego Medical Center, San Diego, California
  • ,
  • Christian Constance, MD

      Affiliations

    • Hopital Maisonneuve-Rosemont Recherche Clinique/Polyclinique, Montreal, Quebec, Canada
  • ,
  • Steven Bird, MS

      Affiliations

    • Merck & Company, Inc., North Wales, Pennsylvania
  • ,
  • Raymond Lee, BS

      Affiliations

    • Merck & Company, Inc., North Wales, Pennsylvania
  • ,
  • Mary E. Hanson, PhD

      Affiliations

    • Merck & Company, Inc., North Wales, Pennsylvania
  • ,
  • Charlotte Jones-Burton, MD, MS

      Affiliations

    • Merck & Company, Inc., North Wales, Pennsylvania
  • ,
  • Andrew M. Tershakovec, MD, MPH

      Affiliations

    • Merck & Company, Inc., North Wales, Pennsylvania

Received 3 August 2009; received in revised form 18 October 2009; accepted 18 October 2009. published online 25 December 2009.

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 Dr. Zieve has received research grants from Amylin Pharmaceuticals, Inc., San Diego, California, Abbott Laboratories, Abbot Park, Illinois, GlaxoSmithKline, London, England, Roche, Basel, Switzerland, Novo-Nordisk, Bagsvaerd, Denmark, Merck & Company, Inc., North Wales, Pennsylvania, and Novartis, Basel, Switzerland; has served on the Speaker's Bureau for Merck & Company, Inc., Abbott Laboratories, and GlaxoSmithKline; and holds stock in Johnson & Johnson, Langhorne, Pennsylvania. Dr. Wenger has received research grants or contracts or has been on the trial steering committee or trial adjudication committee for Pfizer, New York, New York, Merck & Company, Inc., North Wales, Pennsylvania, National Heart, Lung, and Blood Institute, Bethesda, Maryland, CV Therapeutics, Palo Alto, California, Abbott Laboratories, Abbott Park, Illinois, Sanofi-Aventis, Bridgewater, New Jersey, Eli Lilly, Indianapolis, Indiana and has acted as a consultant or advisor for Schering-Plough, Kenilworth, New Jersey; AstraZeneca, Wilmington, Delaware; Abbott Laboratories, Abbott Park, Illinois; Merck & Company, Inc., North Wales, Pennsylvania; Pfizer, New York, New York; Boston Scientific, Boston, Massachusetts; and Medtronic, Minneapolis, Minnesota. Dr. Constance has served on the Speaker's Bureau for Merck & Company, Inc., North Wales, Pennsylvania. Dr. Ben-Yehuda has received research grants from Merck & Company, Inc., North Wales, Pennsylvania, and Merck/Schering-Plough, North Wales, Pennsylvania, has served on the Speaker's Bureau for Schering-Plough, Kenilworth, New Jersey, and has acted as a consultant for CV Therapeutics, Palo Alto, California, and Merck & Company, Inc., Drs. Bird, Lee, Hanson, Jones-Burton, and Tershakovec are employees of Merck & Company, Inc., North Wales, Pennsylvania, and might own stock and/or hold stock options in the company.

 All authors were involved in at least one of the following: conception, design, acquisition, analysis, statistical analysis, interpretation of data, drafting the manuscript, and/or revising the manuscript for important intellectual content. All authors provided final approval of the version to be published.

PII: S0002-9149(09)02552-1

doi:10.1016/j.amjcard.2009.10.029

American Journal of Cardiology
Volume 105, Issue 5 , Pages 656-663, 1 March 2010