American Journal of Cardiology
Volume 105, Issue 2 , Pages 205-209 , 15 January 2010

Do Differences in Subclinical Cardiovascular Disease in Mexican Americans Versus European Americans Help Explain the Hispanic Paradox?

  • Julius M. Gardin, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, St. John Hospital and Medical Center and Wayne State University, Detroit, Michigan
    • Corresponding Author InformationCorresponding author: Tel: (201) 996-3500; fax: (201) 996-3298
  • ,
  • Zuhair Allebban, PhD

      Affiliations

    • Division of Cardiology, Department of Medicine, St. John Hospital and Medical Center and Wayne State University, Detroit, Michigan
  • ,
  • Nathan D. Wong, PhD

      Affiliations

    • University of California, Irvine, Irvine, California
  • ,
  • Sharon K. Sklar, LPN

      Affiliations

    • Division of Cardiology, Department of Medicine, St. John Hospital and Medical Center and Wayne State University, Detroit, Michigan
  • ,
  • Renee L. Bess, RDCS

      Affiliations

    • Division of Cardiology, Department of Medicine, St. John Hospital and Medical Center and Wayne State University, Detroit, Michigan
  • ,
  • M. Anne Spence, PhD

      Affiliations

    • University of California, Irvine, Irvine, California
  • ,
  • Harrihar A. Pershadsingh, MD, PhD

      Affiliations

    • Kern Medical Center, Bakersfield, California
  • ,
  • Robert Detrano, MD, PhD

      Affiliations

    • Department of Medicine, Harbor-UCLA Medical Center, Torrance, California

Received 17 July 2009 ,Revised 25 August 2009 ,Accepted 25 August 2009.

References 

  1. Friis R, Nanjundappa G, Prendergast TJ, Welsh M. Coronary heart disease mortality and risk among Hispanics and non-Hispanics in Orange County, California. Pub Health Rep. 1981;96:418–422
  2. Mitchell BD, Hazuda HP, Haffner SM, Patterson JK, Stern MP. Myocardial infarction in Mexican-Americans and non-Hispanic whites: the San Antonio Heart Study. Circulation. 1991;83:45–51
  3. Nichaman MZ, Wear ML, Goff DC, Labarthe DR. Hospitalization rates for myocardial infarction among Mexican-Americans and non-Hispanic whites: the Corpus Christi Heart Project. Ann Epidemiol. 1993;3:42–48
  4. Goff DC, Varas C, Ramsey DJ, Wear ML, Labarthe DR, Nichaman MZ. Mortality after hospitalization for myocardial infarction among Mexican Americans and non-Hispanic whites: the Corpus Christi Heart project. Ethn Dis. 1993;3:55–63
  5. Gardin JM, Wong ND, Bommer W, Klopfenstein HS, Smith VE, Tabatznik B, et al. Echocardiographic design of a multicenter investigation of free-living elderly subjects: the Cardiovascular Health Study. J Am Soc Echocardiogr. 1992;5:63–72
  6. Gardin JM, Wagenknecht LE, Anton-Culver H, Flack J, Gidding S, Kurosaki T, et al. Relationship of cardiovascular risk factors to echocardiographic left ventricular mass in healthy young black and white adult men and women: the CARDIA study (Coronary Artery Risk Development in Young Adults). Circulation. 1995;92:380–387
  7. Devereux RB, Alonso DR, Lutas EM, Gottlieb GJ, Campo E, Sachs I, et al. Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. Am J Cardiol. 1986;57:450–458
  8. Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP. Left ventricular mass and incidence of coronary heart disease in an elderly cohort: the Framingham Heart Study. Ann Intern Med. 1989;110:101–107
  9. Agatston AS, Janowitz WR, Hildner FJ, Zusmer NR, Viamonte M, Detrano R. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol. 1990;15:827–832
  10. Rewers M, Shetterly SM, Hoag S, Baxter J, Marshall J, Hamman RF. Is the risk of coronary heart disease lower in Hispanics than in non-Hispanics whites? (The San Luis Valley Diabetes study). Ethn Dis. 1993;3:44–54
  11. Bild DE, Detrano R, Peterson D, Guerci A, Liu K, Shahar E, et al. Ethnic differences in coronary calcification: the Multi-Ethnic Study of Atherosclerosis (MESA). Circulation. 2005;111:1313–1320
  12. Detrano R, Guerci AD, Carr JJ, Bild DE, Burke G, Folsom AR, et al. Coronary calcium as a predictor of coronary events in four racial or ethnic groups. N Engl J Med. 2008;358:1336–1345
  13. Wang S, Detrano RC, Secci A, Tang W, Doherty TM, Puentes G, et al. Detection of coronary calcification with electron-beam computed tomography: evaluation of interexamination reproducibility and comparison of three image-acquisition protocols. Am Heart J. 1996;132:550–558
  14. Wexler L, Brundage B, Crouse J, Detrano R, Fuster V, Maddahi J, et al. Coronary artery calcification: pathophysiology, epidemiology, imaging methods, and clinical implications: a statement for health professionals from the American Heart Association (Writing Group). Circulation. 1996;94:1175–1192
  15. Arad Y, Spadaro LA, Goodman K, Newstein D, Guerci AD. Prediction of coronary events with electron beam computed tomography. J Am Coll Cardiol. 2000;36:1253–1260
  16. Gutfinger DE, Leung CY, Hiro T, Maheswaran B, Nakamura S, Detrano R, et al. In vitro atherosclerotic plaque and calcium quantitation by intravascular ultrasound and electron-beam computed tomography. Am Heart J. 1996;131:899–906
  17. Haider AW, Larson MG, Benjamin EJ, Levy D. Increased left ventricular mass and hypertrophy are associated with increased risk for sudden death. J Am Coll Cardiol. 1998;32:1454–1459
  18. Krumholz HM, Larson M, Levy D. Prognosis of left ventricular geometric patterns in the Framingham heart study. J Am Coll Cardiol. 1995;25:879–884
  19. Verdecchia P, Angeli F, Gattobigio R, Sardone M, Porcellati C. Asymptomatic left ventricular systolic dysfunction in essential hypertension: prevalence, determinants, and prognostic value. Hypertension. 2005;45:412–418
  20. Gardin JM, Brunner D, Schreiner PJ, Xie X, Reid CL, Ruth K, et al. Demographics and correlates of five-year changes in echocardiographic left ventricular mass in young black and white adult men and women: the Coronary Artery Risk Development in Young Adults (CARDIA) study. J Am Coll Cardiol. 2002;40:529–535
  21. Detrano R, Carr J. Computed tomography of the heart. In:  Topol EJ editors. Textbook of Cardiovascular Medicine, 2nd ed. Philadelphia: Lippincott Williams & Wilkins; 2002;p. 1281–1296
  22. Gardin JM. How reliable are serial echocardiographic measurements in detecting regression in left ventricular hypertrophy and changes in function?. J Am Coll Cardiol. 1999;34:1633–1636

 This study was supported in part by a Grant-in-Aid from the American Heart Association National Center, Dallas, Texas.

PII: S0002-9149(09)02326-1

doi: 10.1016/j.amjcard.2009.08.673

American Journal of Cardiology
Volume 105, Issue 2 , Pages 205-209 , 15 January 2010