American Journal of Cardiology
Volume 105, Issue 2 , Pages 186-191 , 15 January 2010

Usefulness of Neutrophil/Lymphocyte Ratio As Predictor of New-Onset Atrial Fibrillation After Coronary Artery Bypass Grafting

  • Patrick H. Gibson, BMBCh

      Affiliations

    • Department of Cardiology, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, United Kingdom
    • ,
  • Brian H. Cuthbertson, MBChB, MD

      Affiliations

    • Health Services Research Unit, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, United Kingdom
    • ,
  • Bernard L. Croal, MBChB, MD

      Affiliations

    • Department of Clinical Biochemistry, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, United Kingdom
    • ,
  • Daniela Rae, RN

      Affiliations

    • Health Services Research Unit, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, United Kingdom
    • ,
  • Hussein El-Shafei, MBChB, MD

      Affiliations

    • Department of Cardiac Surgery, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, United Kingdom
    • ,
  • George Gibson, MBChB

      Affiliations

    • Department of Cardiac Surgery, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, United Kingdom
    • ,
  • Robert R. Jeffrey, MBChB

      Affiliations

    • Department of Cardiac Surgery, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, United Kingdom
    • ,
  • Keith G. Buchan, MBChB

      Affiliations

    • Department of Cardiac Surgery, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, United Kingdom
    • ,
  • Graham S. Hillis, MBChB, PhD

      Affiliations

    • Department of Cardiology, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, United Kingdom
    • Corresponding Author InformationCorresponding author: Tel: (+61) 2-9993-4551; fax: (+61) 2-9993-4502

Received 25 May 2009 ,Revised 4 September 2009 ,Accepted 4 September 2009.

References 

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  3. Aviles RJ, Martin DO, Apperson-Hansen C, Houghtaling PL, Rautaharju P, Kronmal RA, et al. Inflammation as a risk factor for atrial fibrillation. Circulation. 2003;108:3006–3010
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  16. Ramlawi B, Otu H, Mieno S, Boodhwani M, Sodha NR, Clements RT, et al. Oxidative stress and atrial fibrillation after cardiac surgery: a case-control study. Ann Thorac Surg. 2007;84:1166–1172
  17. Fontes ML, Mathew JP, Rinder HM, Zelterman D, Smith BR, Rinder CS Multicenter Study of Perioperative Ischemia (McSPI) Research Group. Atrial fibrillation after cardiac surgery/cardiopulmonary bypass is associated with monocyte activation. Anesth Analg. 2005;101:17–23
  18. Ucar HI, Tok M, Atalar E, Dogan OF, Oc M, Farsak B, et al. Predictive significance of plasma levels of interleukin-6 and high-sensitivity C-reactive protein in atrial fibrillation after coronary artery bypass surgery. Heart Surg Forum. 2007;10:E131–E135
  19. Ahlsson AJ, Bodin L, Lundblad OH, Englund AG. Postoperative atrial fibrillation is not correlated to C-reactive protein. Ann J Thorac Surg. 2007;83:1332–1337
  20. Gasz B, Lenard L, Benko L, Borsiczky B, Szanto Z, Lantos J, et al. Expression of CD97 and adhesion molecules on circulating leukocytes in patients undergoing coronary artery bypass surgery. Eur Surg Res. 2005;37:281–289
  21. Ommen SR, Gibbons RJ, Hodge DO, Thomson SP. Usefulness of the lymphocyte concentration as a prognostic marker in coronary artery disease. Am J Cardiol. 1997;79:812–814
  22. Ommen SR, Hodge DO, Rodeheffer RJ, McGregor CG, Thomson SP, Gibbons RJ. Predictive power of the relative lymphocyte concentration in patients with advanced heart failure. Circulation. 1998;97:19–22

 This study was supported by Chest, Heart and Stroke, Scotland (Edinburgh, United Kingdom) and the British Heart Foundation (London, United Kingdom).

PII: S0002-9149(09)02318-2

doi: 10.1016/j.amjcard.2009.09.007

American Journal of Cardiology
Volume 105, Issue 2 , Pages 186-191 , 15 January 2010

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