American Journal of Cardiology
Volume 104, Issue 12 , Pages 1647-1653 , 15 December 2009

Optimal Medical Therapy With or Without Percutaneous Coronary Intervention for Patients With Stable Coronary Artery Disease and Chronic Kidney Disease

  • Steven P. Sedlis, MD

      Affiliations

    • Veterans Affairs New York Harbor Health Care System, and New York University School of Medicine, New York, New York
    • Corresponding Author InformationCorresponding author: Tel: (212) 951-3335; fax: (212) 951-3334
    • ,
  • Claudine T. Jurkovitz, MD, MPH

      Affiliations

    • Christiana Care Health System, Newark, Delaware
    • ,
  • Pamela M. Hartigan, PhD

      Affiliations

    • Veterans Affairs Cooperative Studies Program Coordinating Center and Veterans Affairs Connecticut Health Care System, West Haven, Connecticut
    • ,
  • David S. Goldfarb, MD

      Affiliations

    • Veterans Affairs New York Harbor Health Care System, and New York University School of Medicine, New York, New York
    • ,
  • Jeffrey D. Lorin, MD

      Affiliations

    • Veterans Affairs New York Harbor Health Care System, and New York University School of Medicine, New York, New York
    • ,
  • Marcin Dada, MD

      Affiliations

    • Hartford Hospital, Hartford, Connecticut
    • ,
  • David J. Maron, MD

      Affiliations

    • Vanderbilt University Medical Center, Nashville, Tennessee
    • ,
  • John A. Spertus, MD

      Affiliations

    • Mid America Heart Institute, Kansas City, Missiouri
    • ,
  • G.B. John Mancini, MD

      Affiliations

    • Vancouver Hospital, Cardiovascular Imaging Research Core Laboratory, University of British Columbia, Vancouver, British Columbia, Canada
    • ,
  • Koon K. Teo, MBBCh, PhD

      Affiliations

    • McMaster University Medical Centre, Hamilton, Ontario, Canada
    • ,
  • Robert A. O'Rourke, MD

      Affiliations

    • Veterans Affairs South Texas Health Care System, San Antonio, Texas
    • ,
  • William E. Boden, MD

      Affiliations

    • Veterans Affairs Western New York Health Care System and Kaleida Health, Buffalo, New York
    • ,
  • William S. Weintraub, MD

      Affiliations

    • Christiana Care Health System, Newark, Delaware
    • ,
  • COURAGE Study Investigators

Received 12 June 2009 ,Revised 19 July 2009 ,Accepted 19 July 2009.

References 

  1. Charytan D, Kunitz RE. The exclusion of patients with chronic kidney disease from clinical trials in coronary artery disease. Kidney Int. 2006;70:2021–2030
  2. Coca SG, Krumholz HM, Garg AX, Parikh CR. Underrepresentation of renal disease in randomized controlled trials of cardiovascular disease. JAMA. 2006;296:1377–1384
  3. Dangas G, Iakavou I, Nikolsky E, Aymong ED, Mintz GS, Kipshidze NN, et al. Contrast-induced nephropathy after percutaneous coronary interventions in relation to chronic kidney disease and hemodynamic variables. Am J Cardiol. 2005;95:13–19
  4. Boden WE, O'Rourke RA, Teo KK, Hartigan PM, Maron DJ, Kostuk WJ, et al. Optimal medical therapy with or without PCI for stable coronary disease. N Engl J Med. 2007;356:1503–1516
  5. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D Modification of Diet in Renal Disease Study Group. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Ann Intern Med. 1999;130:461–470
  6. Charlson M, Szatrowski TP, Peterson K, Gold J. Validation of a combined comorbidity index. J Clin Epidemiol. 1994;47:1245–1251
  7. Harper CR, Jacobson TA. Managing dyslipidemia in chronic kidney disease. J Am Coll Cardiol. 2008;51:2375–2384
  8. NKF KDOQI Guidelines. www.kidney.org/professionals/kdoqi/guideline_diabetes/guide3.htmAccessed August 4, 2009
  9. 2007 Chronic Angina Focused Update of the ACC/AHA 2002 Guidelines for the Management of Patients with Chronic Stable angina. www.content.onlinejacc.org/cgi/reprint/j.jacc.2007.08.002v1.pdfAccessed August 4, 2009
  10. Herzog CA, Ma JM, Collins AJ. Comparative survival of dialysis patients in the United States after coronary angioplasty, coronary stenting and coronary artery bypass surgery and impact of diabetes. Circulation. 2002;106:2207–2211
  11. Keeley EC, Kadakia R, Soman S, Borzak S, McCullough PA. Analysis of long-term survival after revascularization in patients with chronic kidney disease presenting with acute coronary syndromes. Am J Cardiol. 2003;92:509–514
  12. McCullough PA. Why is chronic kidney disease the spoiler for cardiovascular outcomes?. J Am Coll Cardiol. 2003;41:725–728

 The trial was sponsored and oversight was provided by the Cooperative Studies Program of the US Department of Veterans Affairs Office of Research and Development. Additional funding was provided by the Canadian Institutes of Health Research. Supplemental corporate support consisted of unrestricted research grants payable to the Department of Veterans Affairs.

PII: S0002-9149(09)01474-X

doi: 10.1016/j.amjcard.2009.07.043

American Journal of Cardiology
Volume 104, Issue 12 , Pages 1647-1653 , 15 December 2009

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