American Journal of Cardiology
Volume 104, Issue 11 , Pages 1490-1493 , 1 December 2009

Prognostic Significance of QRS Duration in Patients With Suspected Coronary Artery Disease Referred for Noninvasive Evaluation of Myocardial Ischemia

  • Arend F.L. Schinkel, MD

      Affiliations

    • Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    • Division of Pharmacology, Vascular and Metabolic Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
    • Corresponding Author InformationCorresponding author: Tel: 31-10-703-9222; fax: 31-10-703-5498
    • ,
  • Abdou Elhendy, MD

      Affiliations

    • Department of Cardiology, Marshfield Clinic, Marshfield, Wisconsin
    • ,
  • Ron T. van Domburg, PhD

      Affiliations

    • Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Elena Biagini, MD

      Affiliations

    • Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Vittoria Rizzello, MD

      Affiliations

    • Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Caroline E. Veltman, MD

      Affiliations

    • Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Gerrit L. ten Kate, MD

      Affiliations

    • Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    • Division of Pharmacology, Vascular and Metabolic Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Eric J. Sijbrands, MD

      Affiliations

    • Division of Pharmacology, Vascular and Metabolic Diseases, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • K. Martijn Akkerhuis, MD

      Affiliations

    • Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Marcel L. Geleijnse, MD

      Affiliations

    • Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Folkert J. ten Cate, MD

      Affiliations

    • Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Maarten L. Simoons, MD

      Affiliations

    • Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Jeroen J. Bax, MD

      Affiliations

    • Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    • ,
  • Don Poldermans, MD

      Affiliations

    • Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands

Received 10 June 2009 ,Revised 8 July 2009 ,Accepted 8 July 2009.

References 

  1. Silvet H, Amin J, Padmanabhan S, Pai RG. Prognostic implications of increased QRS duration in patients with moderate and severe left ventricular systolic dysfunction. Am J Cardiol. 2001;88:182–185
  2. Yamada T, Shimonagata T, Misaki N, Asai M, Makino N, Kioka H, et al. Usefulness of spatial dispersion of QRS duration in predicting mortality in patients with mild to moderate chronic heart failure. Am J Cardiol. 2004;94:960–963
  3. Guttigoli AB, Wilner BF, Stein KM, Markowitz SM, Iwai S, Shah BK, et al. Usefulness of prolonged QRS duration to identify high-risk ischemic cardiomyopathy patients with syncope and inducible ventricular tachycardia. Am J Cardiol. 2005;95:391–394
  4. Surawicz B, Childers R, Deal BJ, Gettes LS, Bailey JJ, Gorgels A, et al. AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part III: intraventricular conduction disturbances: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society. Endorsed by the International Society for Computerized Electrocardiology. J Am Coll Cardiol. 2009;53:976–981
  5. Biagini E, Elhendy A, Schinkel AF, Rizzello V, van Domburg RT, Krenning BJ, et al. Comparison of all-cause mortality in women with known or suspected coronary artery disease referred for dobutamine stress echocardiography with normal versus abnormal test results. Am J Cardiol. 2005;95:1072–1075
  6. Sozzi FB, Poldermans D, Bax JJ, Boersma E, Vletter WB, Elhendy A, et al. Second harmonic imaging improves sensitivity of dobutamine stress echocardiography for the diagnosis of coronary artery disease. Am Heart J. 2001;14:153–159
  7. Cox DR. Regression models and life-tables. J R Stat Soc B. 1972;34:187–202
  8. Wong CK, Gao W, Stewart RA, van Pelt N, French JK, Aylward PE, et al. Risk stratification of patients with acute anterior myocardial infarction and right bundle-branch block: importance of QRS duration and early ST-segment resolution after fibrinolytic therapy. Circulation. 2006;114:783–789

PII: S0002-9149(09)01348-4

doi: 10.1016/j.amjcard.2009.07.012

American Journal of Cardiology
Volume 104, Issue 11 , Pages 1490-1493 , 1 December 2009

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