American Journal of Cardiology
Volume 104, Issue 11 , Pages 1499-1504 , 1 December 2009

Comparison of the Value of Coronary Calcium Detection to Computed Tomographic Angiography and Exercise Testing in Patients With Chest Pain

  • Koen Nieman, MD, PhD

      Affiliations

    • Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • Corresponding Author InformationCorresponding author: Tel: 31-10-7025029; fax: 31-10-703-5242
  • ,
  • Tjebbe W. Galema, MD

      Affiliations

    • Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
  • ,
  • Lisan A. Neefjes, MD

      Affiliations

    • Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands
  • ,
  • Annick C. Weustink, MD

      Affiliations

    • Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands
  • ,
  • Paul Musters

      Affiliations

    • Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
  • ,
  • Adriaan D. Moelker, MD, PhD

      Affiliations

    • Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands
  • ,
  • Nico R. Mollet, MD, PhD

      Affiliations

    • Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands
  • ,
  • Randall de Visser, MD

      Affiliations

    • Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
  • ,
  • Eric Boersma, MD, PhD

      Affiliations

    • Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
  • ,
  • Pim J. de Feijter, MD, PhD

      Affiliations

    • Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
    • Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands

Received 6 May 2009 ,Revised 7 July 2009 ,Accepted 7 July 2009.

References 

  1. Budoff MJ, Achenbach S, Blumenthal RS, Carr JJ, Goldin JG, Greenland P, et al. Assessment of coronary artery disease by cardiac computed tomography: a scientific statement from the AHA Committee on Cardiovascular Imaging and Intervention, Council on Cardiovascular Radiology and Intervention, and Committee on Cardiac Imaging, Council on Clinical Cardiology. Circulation. 2006;114:1761–1791
  2. Schroeder S, Achenbach S, Bengel F, Burgstahler C, Cademartiri F, de Feyter P, et al. Cardiac computed tomography: indications, applications, limitations, and training requirements: report of a writing group deployed by the Working Group Nuclear Cardiology and Cardiac CT of the European Society of Cardiology and the European Council of Nuclear Cardiology (Working Group Nuclear Cardiology and Cardiac CT; European Society of Cardiology; European Council of Nuclear Cardiology). Eur Heart J. 2008;29:531–556
  3. Budoff MJ, Shavelle DM, Lamont DH, Kim HT, Akinwale P, Kennedy JM, et al. Usefulness of electron beam computed tomography scanning for distinguishing ischemic from nonischemic cardiomyopathy. J Am Coll Cardiol. 1998;32:1173–1178
  4. Georgiou D, Budoff MJ, Kaufer E, Kennedy JM, Lu B, Brundage BH. Screening patients with chest pain in the emergency department using electron beam tomography: a follow-up study. J Am Coll Cardiol. 2001;38:105–110
  5. Diamond GA, Forrester JS. Analysis of probability as an aid in the clinical diagnosis of coronary-artery disease. N Engl J Med. 1979;300:1350–1358
  6. Agatston AS, Janowitz WR, Hildner FJ, Zusmer NR, Viamonte M, Detrano R. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol. 1990;15:827–832
  7. Hausleiter J, Meyer T, Hermann F, Hadamitzky M, Krebs M, Gerber TC, et al. Estimated radiation dose associated with cardiac CT angiography. JAMA. 2009;301:500–507
  8. Arad Y, Goodman KJ, Roth M, Newstein D, Guerci AD. Coronary calcification, coronary disease risk factors, C-reactive protein, and atherosclerotic cardiovascular disease events: the St. Francis Heart Study. J Am Coll Cardiol. 2005;46:158–165
  9. Greenland P, LaBree L, Azen SP, Doherty TM, Detrano RC. Coronary artery calcium score combined with Framingham score for risk prediction in asymptomatic individuals. JAMA. 2004;291:210–215
  10. Keelan PC, Bielak LF, Ashai K, Jamjoum LS, Denktas AE, Rumberger JA, et al. Long-term prognostic value of coronary calcification detected by electron-beam computed tomography in patients undergoing coronary angiography. Circulation. 2001;104:412–417
  11. Cheng VY, Lepor NE, Madyoon H, Eshaghian S, Naraghi AL, Shah PK. Presence and severity of noncalcified coronary plaque on 64-slice computed tomographic coronary angiography in patients with zero and low coronary artery calcium. Am J Cardiol. 2007;99:1183–1186
  12. Hacker M, Jakobs T, Matthiesen F, Vollmar C, Nikolaou K, Becker C, et al. Comparison of spiral multidetector CT angiography and myocardial perfusion imaging in the noninvasive detection of functionally relevant coronary artery lesions: first clinical experiences. J Nucl Med. 2005;46:1294–1300
  13. Schuijf JD, Wijns W, Jukema JW, Atsma DE, de Roos A, Lamb HJ, et al. Relationship between noninvasive coronary angiography with multi-slice computed tomography and myocardial perfusion imaging. J Am Coll Cardiol. 2006;48:2508–2514
  14. Ravipati G, Aronow WS, Lai H, Shao J, DeLuca AJ, Weiss MB, et al. Comparison of sensitivity, specificity, positive predictive value, and negative predictive value of stress testing versus 64-multislice coronary computed tomography angiography in predicting obstructive coronary artery disease diagnosed by coronary angiography. Am J Cardiol. 2008;101:774–775
  15. Dewey M, Dübel HP, Schink T, Baumann G, Hamm B. Head-to-head comparison of multislice computed tomography and exercise electrocardiography for diagnosis of coronary artery disease. Eur Heart J. 2007;28:2485–2490
  16. Mollet NR, Cademartiri F, Van Mieghem C, Meijboom B, Pugliese F, Runza G, et al. Adjunctive value of CT coronary angiography in the diagnostic work-up of patients with typical angina pectoris. Eur Heart J. 2007;28:1872–1878
  17. Ropers D, Rixe J, Anders K, Küttner A, Baum U, Bautz W, et al. Usefulness of multidetector row spiral computed tomography with 64- × 0.6-mm collimation and 330-ms rotation for the noninvasive detection of significant coronary artery stenoses. Am J Cardiol. 2006;97:343–348
  18. Leschka S, Alkadhi H, Plass A, Desbiolles L, Grunenfelder J, Marincek B, et al. Accuracy of MSCT coronary angiography with 64-slice technology: first experience. Eur Heart J. 2005;26:1482–1487
  19. Gibbons RJ, Balady GJ, Bricker JT, Chaitman BR, Fletcher GF, Froelicher VF, et al. ACC/AHA 2002 guideline update for exercise testing: summary article: a report of the American College of Cardiology/American Heart Association task force on practice guidelines (committee to update the 1997 exercise testing guidelines). Circulation. 2002;106:1883–1892
  20. Hachamovitch R, Berman DS, Kiat H, Cohen I, Cabico JA, Friedman J, et al. Exercise myocardial perfusion SPECT in patients without known coronary artery disease: incremental prognostic value and use in risk stratification. Circulation. 1996;93:905–914
  21. Hamon M, Biondi-Zoccai GG, Malagutti P, Agostoni P, Morello R, Valgimigli M, et al. Diagnostic performance of multislice spiral computed tomography of coronary arteries as compared with conventional invasive coronary angiography: a meta-analysis. J Am Coll Cardiol. 2006;48:1896–1910
  22. Miller JM, Rochitte CE, Dewey M, Arbab-Zadeh A, Niinuma H, Gottlieb I, et al. Diagnostic performance of coronary angiography by 64-row CT. N Engl J Med. 2008;359:2324–2336
  23. Meijboom WB, Meijs MF, Schuijf JD, Cramer MJ, Mollet NR, van Mieghem CA, et al. Diagnostic accuracy of 64-slice computed tomography coronary angiography: a prospective, multicenter, multivendor study. J Am Coll Cardiol. 2008;52:2135–2144
  24. Pundziute G, Schuijf JD, Jukema JW, Decramer I, Sarno G, Vanhoenacker PK, et al. Evaluation of plaque characteristics in acute coronary syndromes: non-invasive assessment with multi-slice computed tomography and invasive evaluation with intravascular ultrasound radiofrequency data analysis. Eur Heart J. 2008;29:2373–2381
  25. Graham I, Atar D, Borch-Johnsen K, Boysen G, Burell G, Cifkova R, et al. European guidelines on cardiovascular disease prevention in clinical practice: full text (Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of nine societies and by invited experts)). Eur J Cardiovasc Prev Rehabil. 2007;14(suppl 2):S1–S113

PII: S0002-9149(09)01347-2

doi: 10.1016/j.amjcard.2009.07.011

American Journal of Cardiology
Volume 104, Issue 11 , Pages 1499-1504 , 1 December 2009