American Journal of Cardiology
Volume 104, Issue 9 , Pages 1198-1203 , 1 November 2009

Association of Door-to-Balloon Time and Mortality in Patients ≥65 Years With ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

  • Saif S. Rathore, MPH

      Affiliations

    • Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut
    • Corresponding Author InformationCorresponding author: Tel: 203-737-1675; fax: 203-737-1718
    • ,
  • Jeptha P. Curtis, MD

      Affiliations

    • Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut
    • ,
  • Brahmajee K. Nallamothu, MD, MPH

      Affiliations

    • Health Services Research and Development Center of Excellence, Ann Arbor Veterans Administration Medical Center, Ann Arbor, Michigan
    • Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan
    • ,
  • Yongfei Wang, MS

      Affiliations

    • Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut
    • ,
  • JoAnne Micale Foody, MD

      Affiliations

    • Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut
    • West Haven Veterans Administration Medical Center, West Haven, Connecticut
    • ,
  • Mikhail Kosiborod, MD

      Affiliations

    • Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut
    • ,
  • Frederick A. Masoudi, MD, MSPH

      Affiliations

    • Division of Geriatric Medicine, Department of Medicine, Denver Health Medical Center, Denver, Colorado
    • Division of Cardiology, Department of Medicine, Denver Health Medical Center, Denver, Colorado
    • Division of Cardiology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado
    • Colorado Foundation for Medical Care, Aurora, Colorado
    • ,
  • Edward P. Havranek, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, Denver Health Medical Center, Denver, Colorado
    • Division of Cardiology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado
    • Colorado Foundation for Medical Care, Aurora, Colorado
    • ,
  • Harlan M. Krumholz, MD

      Affiliations

    • Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut
    • Section of Health Policy and Administration, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut
    • Robert Wood Johnson Clinical Scholars Program, Yale University School of Medicine, New Haven, Connecticut
    • Yale–New Haven Hospital Center for Outcomes Research and Evaluation, New Haven, Connecticut

Received 21 April 2009 ,Revised 14 June 2009 ,Accepted 14 June 2009.

References 

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  2. Antoniucci D, Valenti R, Migliorini A, Moschi G, Trapani M, Buonamici P, et al. Relation of time to treatment and mortality in patients with acute myocardial infarction undergoing primary coronary angioplasty. Am J Cardiol. 2002;89:1248–1252
  3. Schomig A, Ndrepepa G, Mehilli J, Schwaiger M, Schulen H, Nekolla S, et al. Therapy-dependent influence of time-to-treatment interval on myocardial salvage in patients with acute myocardial infarction treated with coronary artery stenting or thrombolysis. Circulation. 2003;108:1084–1088
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  14. Cannon CP, Gibson CM, Lambrew CT, Shoultz DA, Levy D, French WJ, et al. Relationship of symptom-onset-to-balloon time and door-to-balloon time with mortality in patients undergoing angioplasty for acute myocardial infarction. JAMA. 2000;283:2941–2947
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 Mr. Rathore is supported by Medical Scientist Training Grant GM07205 from the National Institutes of Health, Bethesda, Maryland. Dr. Nallamothu is supported as a clinical scholar under K12 Grant RR017607-01 from the National Institutes of Health. Dr. Foody is supported by Research Career Award K08-AG20623-01 from the National Institute on Aging, Bethesda, Maryland, and a National Institute on Aging/Hartford Foundation Fellowship in Geriatrics, Bethesda, Maryland. Dr. Masoudi is supported by Research Career Award K08-AG01011 from the National Institute on Aging. This research was supported by Grant R01 HL072575 from the National Heart, Lung and Blood Institute, Bethesda, Maryland. The analyses on which this publication is based were performed under Contract 500-02-CO-01, entitled “Utilization and Quality Control Peer Review Organization for the State of Colorado,” sponsored by the Centers for Medicare and Medicaid Services (formerly Health Care Financing Administration), US Department of Health and Human Services, Baltimore, Maryland. The content of this publication does not necessarily reflect the views or policies of the U.S. Department of Health and Human Services, nor does mention of trade names, commercial products, or organizations imply endorsement by the U.S. Government. The authors assume full responsibility for the accuracy and completeness of the ideas presented. This publication is a direct result of the Health Care Quality Improvement Program initiated by the Health Care Financing Administration, which has encouraged identification of quality improvement projects derived from analysis of patterns of care, and therefore required no special funding on the part of this Contractor. Ideas and contributions to the author concerning experience in engaging with issues presented are welcomed.

PII: S0002-9149(09)01260-0

doi: 10.1016/j.amjcard.2009.06.034

American Journal of Cardiology
Volume 104, Issue 9 , Pages 1198-1203 , 1 November 2009

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