American Journal of Cardiology
Volume 104, Issue 6 , Pages 812-817 , 15 September 2009

Ethnic-Specific Risks for Atherosclerotic Calcification of the Thoracic and Abdominal Aorta (from the Multi-Ethnic Study of Atherosclerosis)

  • Matthew A. Allison, MD

      Affiliations

    • University of California, San Diego, La Jolla, California
    • Corresponding Author InformationCorresponding author: Tel: 858-822-7671; fax: 858-822-7662
  • ,
  • Matthew J. Budoff, MD

      Affiliations

    • Los Angeles Biomedical Research Institute at Harbor–University of California, Los Angeles, Los Angeles, California
  • ,
  • Khurram Nasir, MD

      Affiliations

    • Harvard University, Cambridge, Massachusetts
  • ,
  • Nathan D. Wong, PhD

      Affiliations

    • University of California, Irvine, Irvine, California
  • ,
  • Robert Detrano, MD

      Affiliations

    • University of California, Irvine, Irvine, California
  • ,
  • Richard Kronmal, PhD

      Affiliations

    • University of Washington, Seattle, Washington
  • ,
  • Junichiro Takasu, MD

      Affiliations

    • Los Angeles Biomedical Research Institute at Harbor–University of California, Los Angeles, Los Angeles, California
  • ,
  • Michael H. Criqui, MD

      Affiliations

    • University of California, San Diego, La Jolla, California

Received 20 March 2009 ,Revised 2 May 2009 ,Accepted 2 May 2009.

References 

  1. Allison MA, Criqui MH, Wright CM. Patterns and risk factors for systemic calcified atherosclerosis. Arterioscler Thromb Vasc Biol. 2004;24:331–336
  2. Kuller LH, Matthews KA, Sutton-Tyrrell K, Edmundowicz D, Bunker CH. Coronary and aortic calcification among women 8 years after menopause and their premenopausal risk factors: the healthy women study. Arterioscler Thromb Vasc Biol. 1999;19:2189–2198
  3. Wong ND, Sciammarella M, Arad Y, Miranda-Peats R, Polk D, Hachamovich R, et al. Relation of thoracic aortic and aortic valve calcium to coronary artery calcium and risk assessment. Am J Cardiol. 2003;92:951–955
  4. Wilson PWF, Kauppila LI, O'Donnell CJ, Kiel DP, Hannan M, Polak JM, et al. Abdominal aortic calcific deposits are an important predictor of vascular morbidity and mortality. Circulation. 2001;103:1529–1534
  5. Bild DE, Bluemke DA, Burke GL, Detrano R, Diez Roux AV, Folsom AR, et al. Multi-Ethnic Study of Atherosclerosis: objectives and design. Am J Epidemiol. 2002;156:871–881
  6. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499–502
  7. Breen J, Sheedy P, Schwartz R. Coronary artery calcification detected with ultrafast CT as an indication of coronary artery disease. Radiology. 1992;185:435–439
  8. Carr J, Crouse J, Goff D. Evaluation of sub-second gated helical CT for quantification of coronary artery calcium and comparison with electron beam CT. Am J Radiol. 2000;174:915–921
  9. Agatston AS, Janowitz WR, Hildner FJ, Zusmer NR, Viamonte M, Detrano R. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol. 1990;15:827–832
  10. Bild DE, Detrano R, Peterson D, Guerci A, Liu K, Shahar E, et al. Ethnic differences in coronary calcification: the Multi-Ethnic Study of Atherosclerosis (MESA). Circulation. 2005;111:1313–1320
  11. Zieske AW, Malcom GT, Strong JP. Natural history and risk factors of atherosclerosis in children and youth: the PDAY study. Pediatr Pathol Mol Med. 2002;21:213–237
  12. Wagenknecht LE, Langefeld CD, Freedman BI, Carr JJ, Bowden DW. A comparison of risk factors for calcified atherosclerotic plaque in the coronary, carotid, and abdominal aortic arteries: the Diabetes Heart Study. Am J Epidemiol. 2007;166:340–347
  13. Burke AP, Kutys R, Zieske A, Weber D, Virmani R. Atherosclerotic coronary plaques in African Americans are less likely to calcify than coronary plaques in Caucasian Americans. Circulation. 2002;106(suppl):481
  14. Stary HC. The development of calcium deposits in atherosclerotic lesions and their persistence after lipid regression. Am J Cardiol. 2001;88(suppl):16E–19E
  15. Stary HC, Chandler AB, Dinsmore RE, Fuster V, Glagov S, Insull W, et al. A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis (A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association). Arterioscler Thromb Vasc Biol. 1995;15:1512–1531
  16. Demer LL, Tintut Y. Mineral exploration: search for the mechanism of vascular calcification and beyond: the 2003 Jeffrey M. Hoeg Award lecture. Arterioscler Thromb Vasc Biol. 2003;23:1739–1743
  17. Hyder JA, Allison MA, Criqui MH, Wright CM. Association between systemic calcified atherosclerosis and bone density. Calcif Tissue Int. 2007;80:301–306
  18. Hyder JA, Allison MA, Wong N, Papa A, Lang TF, Sirlin C, et al. Association of coronary artery and aortic calcium with lumbar bone density: the MESA abdominal aortic calcium study. Am J Epidemiol. 2009;169:186–194
  19. Parhami F, Morrow AD, Balucan J, Leitinger N, Watson AD, Tintut Y, et al. Lipid oxidation products have opposite effects on calcifying vascular cell and bone cell differentiation (A possible explanation for the paradox of arterial calcification in osteoporotic patients). Arterioscler Thromb Vasc Biol. 1997;17:680–687
  20. Holvoet P, Jenny NS, Schreiner PJ, Tracy RP, Jacobs DR. The relation between oxidized LDL and other cardiovascular risk factors and subclinical CVD in different ethnic groups: the Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis. 2007;194:245–252

 This research was supported by a grant to Dr. Allison from the American Heart Association, Dallas, Texas; Grant R01 HL071739 from the National Institutes of Health, Bethesda, Maryland; and Contracts N01-HC-95159 through N01-HC-95165 and N01-HC-95169 from the National Heart, Lung, and Blood Institute, Bethesda, Maryland.

PII: S0002-9149(09)01036-4

doi: 10.1016/j.amjcard.2009.05.004

American Journal of Cardiology
Volume 104, Issue 6 , Pages 812-817 , 15 September 2009