American Journal of Cardiology
Volume 104, Issue 5 , Pages 700-706 , 1 September 2009

Impact of Right Ventricular Pacing on Three-Dimensional Global Left Ventricular Dyssynchrony in Children and Young Adults With Congenital and Acquired Heart Block Associated With Congenital Heart Disease

  • Wen-Jing Hong, MD

      Affiliations

    • Division of Paediatric Cardiology, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, China
    • Shanghai Children's Medical Center, Shanghai, China
  • ,
  • Tak-cheung Yung, MBBS

      Affiliations

    • Division of Paediatric Cardiology, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, China
  • ,
  • Kin-shing Lun, MBBS

      Affiliations

    • Division of Paediatric Cardiology, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, China
  • ,
  • Sophia Jessica Wong, BSc

      Affiliations

    • Division of Paediatric Cardiology, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, China
  • ,
  • Yiu-fai Cheung, MD

      Affiliations

    • Division of Paediatric Cardiology, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, China
    • Corresponding Author InformationCorresponding author: Tel: 852-28554090; fax: 852-28551523

Received 18 March 2009 ,Revised 16 April 2009 ,Accepted 16 April 2009.

References 

  1. Kim JJ, Friedman RA, Eidem BW, Cannon BC, Arora G, Smith EO, et al. Ventricular function and long-term pacing in children with congenital complete atrioventricular block. J Cardiovasc Electrophysiol. 2007;18:373–377
  2. Shalganov TN, Paprika D, Vatasescu R, Kardos A, Mihalcz A, Kornyei L, et al. Mid-term echocardiographic follow up of left ventricular function with permanent right ventricular pacing in pediatric patients with and without structural heart disease. Cardiovasc Ultrasound. 2007;5:13
  3. Vatasescu R, Shalganov T, Paprika D, Kornyei L, Prodan Z, Bodor G, et al. Evolution of left ventricular function in paediatric patients with permanent right ventricular pacing for isolated congenital heart block: a medium term follow-up. Europace. 2007;9:228–232
  4. Tantengco MV, Thomas RL, Karpawich PP. Left ventricular dysfunction after long-term right ventricular apical pacing in the young. J Am Coll Cardiol. 2001;37:2093–2100
  5. Thambo JB, Bordachar P, Garrigue S, Lafitte S, Sanders P, Reuter S, et al. Detrimental ventricular remodeling in patients with congenital complete heart block and chronic right ventricular apical pacing. Circulation. 2004;110:3766–3772
  6. Karpawich PP, Rabah R, Haas JE. Altered cardiac histology following apical right ventricular pacing in patients with congenital atrioventricular block. Pacing Clin Electrophysiol. 1999;22:1372–1377
  7. Manolis AS. The deleterious consequences of right ventricular apical pacing: time to seek alternate site pacing. Pacing Clin Electrophysiol. 2006;29:298–315
  8. Tops LF, Suffoletto MS, Bleeker GB, Boersma E, van der Wall EE, Gorcsan J, et al. Speckle-tracking radial strain reveals left ventricular dyssynchrony in patients with permanent right ventricular pacing. J Am Coll Cardiol. 2007;50:1180–1188
  9. Kapetanakis S, Kearney MT, Siva A, Gall N, Cooklin M, Monaghan MJ. Real-time three-dimensional echocardiography: a novel technique to quantify global left ventricular mechanical dyssynchrony. Circulation. 2005;112:992–1000
  10. Helmcke F, Nanda NC, Hsiung MC, Soto B, Adey CK, Goyal RG, et al. Color Doppler assessment of mitral regurgitation with orthogonal planes. Circulation. 1987;75:175–183
  11. Liang XC, Cheung EW, Wong SJ, Cheung YF. Impact of right ventricular volume overload on three-dimensional global left ventricular mechanical dyssynchrony after surgical repair of tetralogy of Fallot. Am J Cardiol. 2008;102:1731–1736
  12. Schiller NB, Shah PM, Crawford M, DeMaria A, Devereux R, Feigenbaum H, et al Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. J Am Soc Echocardiogr. 1989;2:358–367
  13. Sugeng L, Mor-Avi V, Weinert L, Niel J, Ebner C, Steringer-Mascherbauer R, et al. Quantitative assessment of left ventricular size and function: side-by-side comparison of real-time three-dimensional echocardiography and computed tomography with magnetic resonance reference. Circulation. 2006;114:654–661
  14. Mor-Avi V, Jenkins C, Kuhl H, Nesser HJ, Marwick T, Franke A, et al. Real-time 3-dimensional echocardiographic quantification of left ventricular volumes (Multicenter study for validation with magnetic resonance imaging and investigation of sources of error). J Am Coll Cardiol Imaging. 2008;1:413–423
  15. Karpawich PP, Justice CD, Cavitt DL, Chang CH. Developmental sequelae of fixed-rate ventricular pacing in the immature canine heart: an electrophysiologic, hemodynamic, and histopathologic evaluation. Am Heart J. 1990;119:1077–1083
  16. Adomian GE, Beazell J. Myofibrillar disarray produced in normal hearts by chronic electrical pacing. Am Heart J. 1986;112:79–83
  17. Tse HF, Lau CP. Long-term effect of right ventricular pacing on myocardial perfusion and function. J Am Coll Cardiol. 1997;29:744–749
  18. Prinzen FW, Augustijn CH, Arts T, Allessie MA, Reneman RS. Redistribution of myocardial fiber strain and blood flow by asynchronous activation. Am J Physiol. 1990;259:H300–H308
  19. Nothroff J, Norozi K, Alpers V, Arnhold JO, Wessel A, Ruschewski W, et al. Pacemaker implantation as a risk factor for heart failure in young adults with congenital heart disease. Pacing Clin Electrophysiol. 2006;29:386–392
  20. Becker M, Hoffmann R, Schmitz F, Hundemer A, Kuhl H, Schauerte P, et al. Relation of optimal lead positioning as defined by three-dimensional echocardiography to long-term benefit of cardiac resynchronization. Am J Cardiol. 2007;100:1671–1676
  21. Ansalone G, Giannantoni P, Ricci R, Trambaiolo P, Fedele F, Santini M. Doppler myocardial imaging to evaluate the effectiveness of pacing sites in patients receiving biventricular pacing. J Am Coll Cardiol. 2002;39:489–499
  22. Yu CM, Chau E, Sanderson JE, Fan K, Tang MO, Fung WH, et al. Tissue Doppler echocardiographic evidence of reverse remodeling and improved synchronicity by simultaneously delaying regional contraction after biventricular pacing therapy in heart failure. Circulation. 2002;105:438–445
  23. Capasso F, Giunta A, Stabile G, Turco P, La Rocca V, Grimaldi G, et al. Left ventricular functional recovery during cardiac resynchronization therapy: predictive role of asynchrony measured by strain rate analysis. Pacing Clin Electrophysiol. 2005;28(suppl):S1–S4
  24. Rossillo A, Verma A, Saad EB, Corrado A, Gasparini G, Marrouche NF, et al. Impact of coronary sinus lead position on biventricular pacing: mortality and echocardiographic evaluation during long-term follow-up. J Cardiovasc Electrophysiol. 2004;15:1120–1125
  25. Janousek J, Tomek V, Chaloupecky V, Gebauer RA. Dilated cardiomyopathy associated with dual-chamber pacing in infants: improvement through either left ventricular cardiac resynchronization or programming the pacemaker off allowing intrinsic normal conduction. J Cardiovasc Electrophysiol. 2004;15:470–474
  26. Wilkoff BL, Cook JR, Epstein AE, Greene HL, Hallstrom AP, Hsia H, et al. Dual-chamber pacing or ventricular backup pacing in patients with an implantable defibrillator: the Dual Chamber and VVI Implantable Defibrillator (DAVID) trial. JAMA. 2002;288:3115–3123
  27. Sharma AD, Rizo-Patron C, Hallstrom AP, O'Neill GP, Rothbart S, Martins JB, et al. Percent right ventricular pacing predicts outcomes in the DAVID trial. Heart Rhythm. 2005;2:830–834
  28. Kurita T, Onishi K, Dohi K, Tanabe M, Fujimoto N, Tanigawa T, et al. Impact of heart rate on mechanical dyssynchrony and left ventricular contractility in patients with heart failure and normal QRS duration. Eur J Heart Fail. 2007;9:637–643
  29. Spragg DD, Leclercq C, Loghmani M, Faris OP, Tunin RS, DiSilvestre D, et al. Regional alterations in protein expression in the dyssynchronous failing heart. Circulation. 2003;108:929–932

PII: S0002-9149(09)01004-2

doi: 10.1016/j.amjcard.2009.04.036

American Journal of Cardiology
Volume 104, Issue 5 , Pages 700-706 , 1 September 2009