American Journal of Cardiology
Volume 104, Issue 1 , Pages 19-23 , 1 July 2009

Usefulness of Left Ventricular Dyssynchrony After Acute Myocardial Infarction, Assessed by a Tagging Magnetic Resonance Image Derived Metric, as a Determinant of Ventricular Remodeling

  • Sung-A. Chang, MD

      Affiliations

    • Division of Cardiology, Cardiovascular Center, Seoul National University, Bundang Hospital, Gyeonggi-do, Korea
    • Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
    • ,
  • Hyuk-Jae Chang, MD

      Affiliations

    • Division of Cardiology, Cardiovascular Center, Seoul National University, Bundang Hospital, Gyeonggi-do, Korea
    • Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
    • Corresponding Author InformationCorresponding author: Tel: 82-31-787-7009; fax: 82-31-787-4051
    • ,
  • Sang Il Choi, MD

      Affiliations

    • Division of Radiology, Cardiovascular Center, Seoul National University, Bundang Hospital, Gyeonggi-do, Korea
    • ,
  • Eun Ju Chun, MD

      Affiliations

    • Division of Radiology, Cardiovascular Center, Seoul National University, Bundang Hospital, Gyeonggi-do, Korea
    • ,
  • Yeonyee E. Yoon, MD

      Affiliations

    • Division of Cardiology, Cardiovascular Center, Seoul National University, Bundang Hospital, Gyeonggi-do, Korea
    • Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
    • ,
  • Hyung-Kwan Kim, MD

      Affiliations

    • Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
    • ,
  • Yong-Jin Kim, MD

      Affiliations

    • Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
    • ,
  • Dong-Ju Choi, MD

      Affiliations

    • Division of Cardiology, Cardiovascular Center, Seoul National University, Bundang Hospital, Gyeonggi-do, Korea
    • Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
    • ,
  • Dae-Won Sohn, MD

      Affiliations

    • Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
    • ,
  • Robert H. Helm, MD

      Affiliations

    • Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland
    • ,
  • Albert C. Lardo, PhD

      Affiliations

    • Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland

Received 26 November 2008 ,Revised 23 February 2009 ,Accepted 23 February 2009.

References 

  1. Bilchick KC, Dimaano V, Wu KC, Helm RH, Weiss RG, Lima JA, et al. Cardiac magnetic resonance assessment of dyssynchrony and myocardial scar predicts function class improvement following cardiac resynchronization therapy. JACC Cardiovasc Imaging. 2008;1:569–571
  2. Garot J, Bluemke DA, Osman NF, Rochitte CE, McVeigh ER, Zerhouni EA, et al. Fast determination of regional myocardial strain fields from tagged cardiac images using harmonic phase MRI. Circulation. 2000;101:981–988
  3. Axel L, Dougherty L. MR imaging of motion with spatial modulation of magnetization. Radiology. 1989;171:841–845
  4. Zerhouni EA, Parish DM, Rogers WJ, Yang A, Shapiro EP. Human heart: tagging with MR imaging—a method for noninvasive assessment of myocardial motion. Radiology. 1988;169:59–63
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  8. Leclercq C, Faris O, Tunin R, Johnson J, Kato R, Evans F, et al. Systolic improvement and mechanical resynchronization does not require electrical synchrony in the dilated failing heart with left bundle-branch block. Circulation. 2002;106:1760–1763
  9. Zhang Y, Chan AK, Yu CM, Lam WW, Yip GW, Fung WH, et al. Left ventricular systolic asynchrony after acute myocardial infarction in patients with narrow QRS complexes. Am Heart J. 2005;149:497–503
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  11. Mollema SA, Liem SS, Suffoletto MS, Bleeker GB, van der Hoeven BL, van de Veire NR, et al. Left ventricular dyssynchrony acutely after myocardial infarction predicts left ventricular remodeling. J Am Coll Cardiol. 2007;50:1532–1540
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  13. Chung ES, Leon AR, Tavazzi L, Sun JP, Nihoyannopoulos P, Merlino J, et al. Results of the Predictors of Response to CRT (PROSPECT) trial. Circulation. 2008;117:2608–2616
  14. Suffoletto MS, Dohi K, Cannesson M, Saba S, Gorcsan J. Novel speckle-tracking radial strain from routine black-and-white echocardiographic images to quantify dyssynchrony and predict response to cardiac resynchronization therapy. Circulation. 2006;113:960–968
  15. Lim P, Buakhamsri A, Popovic ZB, Greenberg NL, Patel D, Thomas JD, et al. Longitudinal strain delay index by speckle tracking imaging: a new marker of response to cardiac resynchronization therapy. Circulation. 2008;118:1130–1137
  16. White HD, Norris RM, Brown MA, Brandt PW, Whitlock RM, Wild CJ. Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction. Circulation. 1987;76:44–51

PII: S0002-9149(09)00663-8

doi: 10.1016/j.amjcard.2009.02.042

American Journal of Cardiology
Volume 104, Issue 1 , Pages 19-23 , 1 July 2009

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