American Journal of Cardiology
Volume 103, Issue 11 , Pages 1562-1567 , 1 June 2009

Relationship of Thoracic Aortic Calcium to Coronary Calcium and Its Progression (from the Multi-Ethnic Study of Atherosclerosis [MESA])

  • Juan J. Rivera, MD

      Affiliations

    • Division of Cardiology, Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins Hospital, Baltimore, Maryland
    • Corresponding Author InformationCorresponding author: Tel: 410-502-0469; fax: 410-614-9990
    • ,
  • Khurram Nasir, MD, MPH

      Affiliations

    • Division of Cardiology, Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins Hospital, Baltimore, Maryland
    • Department of Medicine, Boston University Medical Center, Boston, Massachusetts
    • ,
  • Ronit Katz, DPhil

      Affiliations

    • Collaborative Health Studies Coordinating Center, University of Washington, Seattle, Washington
    • ,
  • Junichiro Takasu, MD, PhD

      Affiliations

    • Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California
    • ,
  • Matthew Allison, MD, MPH

      Affiliations

    • Department of Family and Preventative Medicine, University of California, San Diego, San Diego, California
    • ,
  • Nathan D. Wong, PhD

      Affiliations

    • Division of Cardiology, University of California, Irvine, Irvine, California
    • ,
  • R. Graham Barr, MD, DrPH

      Affiliations

    • Department of Medicine and Epidemiology, Columbia University, New York, New York
    • ,
  • Jeffrey J. Carr, MD, MSCE

      Affiliations

    • Division of Radiological Sciences, Wake Forest University Health Sciences, Winston-Salem, North Carolina
    • ,
  • Roger S. Blumenthal, MD

      Affiliations

    • Division of Cardiology, Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins Hospital, Baltimore, Maryland
    • ,
  • Matthew J. Budoff, MD

      Affiliations

    • Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California

Received 20 November 2008 ,Revised 5 February 2009 ,Accepted 5 February 2009.

References 

  1. Bild DE, Bluemke DA, Burke GL, Detrano R, Diez Roux AV, Folsom AR, et al Multi-ethnic study of atherosclerosis: objectives and design. Am J Epidemiol. 2002;156:871–881
  2. Carr JJ, Nelson JC, Wong ND, McNitt-Gray M, Arad Y, Jacobs DR, et al. Calcified coronary artery plaque measurement with cardiac CT in population-based studies: standardized protocol of Multi-Ethnic Study of Atherosclerosis (MESA) and Coronary Artery Risk Development in Young Adults (CARDIA) study. Radiology. 2005;234:35–43
  3. Kronmal RA, McClelland RL, Detrano R, Shea S, Lima JA, Cushman M, et al. Risk factors for the progression of coronary artery calcification in asymptomatic subjects: results from the Multi-Ethnic Study of Atherosclerosis (MESA). Circulation. 2007;115:2722–2730
  4. Takasu J, Katz R, Nasir K, Carr JJ, Wong N, Detrano R, et al. Relationship of thoracic aortic wall calcification to cardiovascular risk factors: the Multi-Ethnic Study of Atherosclerosis (MESA). Am Heart J. 2008;155:765–771
  5. Chironi G, Simon A, Denarie N, Denarie N, Vedie B, Sene V, et al. Determinants of progression of coronary artery calcifications in asymptomatic men at high cardiovascular risk. Angiology. 2002;53:677–683
  6. Yoon HC, Emerick AM, Hill JA, Gjertson DW, Goldin JG. Calcium begets calcium: progression of coronary artery calcification in asymptomatic subjects. Radiology. 2002;224:236–241
  7. Kuller LH, Matthews KA, Edmundowicz D, Chang Y. Incident coronary artery calcium among postmenopausal women. Atherosclerosis. 2008;200:278–285
  8. Taylor AJ, Bindeman J, Le TP, Bauer K, Byrd C, Feuerstein IM, et al. Progression of calcified coronary atherosclerosis: relationship to coronary risk factors and carotid intima-media thickness. Atherosclerosis. 2008;197:339–345

 This research was supported by Grants R01-HL-63963-01A1 and R01-HL-071739-03 and Contracts N01-HC-95159 through N01-HC-95165 and N01-HC-95169 from the National Heart, Lung, and Blood Institute, Bethesda, Maryland. Dr. Nasir is supported by Grant 1T32 HL076136-02 from the National Institutes of Health, Bethesda, Maryland.

PII: S0002-9149(09)00538-4

doi: 10.1016/j.amjcard.2009.02.004

American Journal of Cardiology
Volume 103, Issue 11 , Pages 1562-1567 , 1 June 2009

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