American Journal of Cardiology
Volume 103, Issue 8 , Pages 1083-1088 , 15 April 2009

Serial Intravascular Ultrasound Analysis of Peri-Stent Remodeling and Proximal and Distal Edge Effects After Sirolimus-Eluting or Paclitaxel-Eluting Stent Implantation in Patients With Diabetes Mellitus

  • Lisette Okkels Jensen, MD, PhD

      Affiliations

    • Department of Cardiology, Odense University Hospital, Odense, Denmark
    • Corresponding Author InformationCorresponding author: Tel: +45-6541-2691; fax: +45-6312-1730
    • ,
  • Michael Maeng, MD, PhD

      Affiliations

    • Department of Cardiology, Aarhus University Hospital, Skejby Hospital, Aarhus, Denmark
    • ,
  • Gary S. Mintz, MD

      Affiliations

    • Cardiovascular Research Foundation, New York, New York
    • ,
  • Evald Hoej Christiansen, MD, PhD

      Affiliations

    • Department of Cardiology, Aarhus University Hospital, Skejby Hospital, Aarhus, Denmark
    • ,
  • Knud Noerregaard Hansen, MD

      Affiliations

    • Department of Cardiology, Odense University Hospital, Odense, Denmark
    • ,
  • Anders Galloe, MD, PhD

      Affiliations

    • Department of Cardiology, Gentofte Hospital, University of Copenhagen, Gentofte, Denmark
    • ,
  • Henning Kelbaek, MD, DMSci

      Affiliations

    • Department of Cardiology, Rigshospitalet, Copenhagen, Denmark
    • ,
  • Jens Flensted Lassen, MD, PhD

      Affiliations

    • Department of Cardiology, Aarhus University Hospital, Skejby Hospital, Aarhus, Denmark
    • ,
  • Leif Thuesen, MD, DMSci

      Affiliations

    • Department of Cardiology, Aarhus University Hospital, Skejby Hospital, Aarhus, Denmark
    • ,
  • Per Thayssen, MD, DMSci

      Affiliations

    • Department of Cardiology, Odense University Hospital, Odense, Denmark

Received 4 December 2008 ,Revised 21 December 2008 ,Accepted 21 December 2008.

References 

  1. Abizaid A, Kornowski R, Mintz GS, Hong MK, Abizaid AS, Mehran R, et al. The influence of diabetes mellitus on acute and late clinical outcomes following coronary stent implantation. J Am Coll Cardiol. 1998;32:584–589
  2. Kornowski R, Mintz GS, Kent KM, Pichard AD, Satler LF, Bucher TA, et al. Increased restenosis in diabetes mellitus after coronary interventions is due to exaggerated intimal hyperplasia (A serial intravascular ultrasound study). Circulation. 1997;95:1366–1369
  3. Mintz GS, Nissen SE, Anderson WD, Bailey SR, Erbel R, Fitzgerald PJ, et al. American College of Cardiology Clinical Expert Consensus Document on Standards for Acquisition, Measurement and Reporting of Intravascular Ultrasound Studies (IVUS) (A report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents). J Am Coll Cardiol. 2001;37:1478–1492
  4. Mintz GS, Weissman NJ. Intravascular ultrasound in the drug-eluting stent era. J Am Coll Cardiol. 2006;48:421–429
  5. Dibra A, Kastrati A, Mehilli J, Pache J, Schuhlen H, von BN, et al. Paclitaxel-eluting or sirolimus-eluting stents to prevent restenosis in diabetic patients. N Engl J Med. 2005;353:663–670
  6. Hermiller JB, Raizner A, Cannon L, Gurbel PA, Kutcher MA, Wong SC, et al. Outcomes with the polymer-based paclitaxel-eluting TAXUS stent in patients with diabetes mellitus: the TAXUS-IV trial. J Am Coll Cardiol. 2005;45:1172–1179
  7. Sabate M, Jimenez-Quevedo P, Angiolillo DJ, Gomez-Hospital JA, Alfonso F, Hernandez-Antolin R, et al Randomized comparison of sirolimus-eluting stent versus standard stent for percutaneous coronary revascularization in diabetic patients: the Diabetes and Sirolimus-Eluting Stent (DIABETES) Trial. Circulation. 2005;112:2175–2183
  8. Jensen LO, Maeng M, Thayssen P, Christiansen EH, Hansen KN, Galloe A, et al. Neointimal hyperplasia after sirolimus-eluting and paclitaxel-eluting stent implantation in diabetic patients: the Randomized Diabetes and Drug-Eluting Stent (DiabeDES) Intravascular Ultrasound Trial. Eur Heart J. 2008;29:2733–2741
  9. Aoki J, Mintz GS, Weissman NJ, Mann JI, Cannon L, Greenberg J, et al. Chronic arterial responses to overlapping paclitaxel-eluting stents. J Am Coll Cardiol Interv. 2008;1:161–167
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  13. Weissman NJ, Wilensky RL, Tanguay JF, Bartorelli AL, Moses J, Williams DO, et al Extent and distribution of in-stent intimal hyperplasia and edge effect in a non-radiation stent population. Am J Cardiol. 2001;88:248–252
  14. Galloe AM, Thuesen L, Kelbaek H, Thayssen P, Rasmussen K, Hansen PR, et al Comparison of paclitaxel- and sirolimus-eluting stents in everyday clinical practice: the SORT OUT II randomized trial. JAMA. 2008;299:409–416
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  17. Weissman NJ, Koglin J, Cox DA, Hermiller J, O'Shaughnessy C, Mann JT, et al Polymer-based paclitaxel-eluting stents reduce in-stent neointimal tissue proliferation: a serial volumetric intravascular ultrasound analysis from the TAXUS-IV trial. J Am Coll Cardiol. 2005;45:1201–1205
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  19. Jimenez-Quevedo P, Sabate M, Angiolillo DJ, Costa MA, Alfonso F, Gomez-Hospital JA, et al Vascular effects of sirolimus-eluting versus bare-metal stents in diabetic patients: three-dimensional ultrasound results of the Diabetes and Sirolimus-Eluting Stent (DIABETES) Trial. J Am Coll Cardiol. 2006;47:2172–2179
  20. Petronio AS, De CM, Branchitta G, Papini B, Ciabatti N, Gistri R, et al. Randomized comparison of sirolimus and paclitaxel drug-eluting stents for long lesions in the left anterior descending artery: an intravascular ultrasound study. J Am Coll Cardiol. 2007;49:539–546
  21. Finn AV, Kolodgie FD, Harnek J, Guerrero LJ, Acampado E, Tefera K, et al. Differential response of delayed healing and persistent inflammation at sites of overlapping sirolimus- or paclitaxel-eluting stents. Circulation. 2005;112:270–278
  22. Pires NM, Eefting D, de Vries MR, Quax PH, Jukema JW. Sirolimus and paclitaxel provoke different vascular pathological responses after local delivery in a murine model for restenosis on underlying atherosclerotic arteries. Heart. 2007;93:922–927
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PII: S0002-9149(09)00043-5

doi: 10.1016/j.amjcard.2008.12.035

American Journal of Cardiology
Volume 103, Issue 8 , Pages 1083-1088 , 15 April 2009

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