American Journal of Cardiology
Volume 103, Issue 7 , Pages 943-949 , 1 April 2009

Usefulness of Coronary Fractional Flow Reserve Measurements in Guiding Clinical Decisions in Intermediate or Equivocal Left Main Coronary Stenoses

Received 27 August 2008 ,Revised 21 November 2008 ,Accepted 21 November 2008.

References 

  1. Pijls NH, De Bruyne B, Peels K, Van Der Voort P, Bonnier H, Bartunek J, et al. Measurement of fractional flow reserve to assess the functional severity of coronary-artery stenoses. N Engl J Med. 1996;334:1703–1708
  2. Bishop AH, Samady H. Fractional flow reserve: critical review of an important physiologic adjunct to angiography. Am Heart J. 2004;147:792–802
  3. Bech GJ, De Bruyne B, Pijls NH, de Muinck ED, Hoorntje JC, Escaned J, et al. Fractional flow reserve to determine the appropriateness of angioplasty in moderate coronary stenosis: a randomized trial. Circulation. 2001;103:2928–2934
  4. Bech GJ, De Bruyne B, Bonnier HJ, Bartunek J, Wijns W, Peels K, et al. Long-term follow-up after deferral of percutaneous transluminal coronary angioplasty of intermediate stenosis on the basis of coronary pressure measurement. J Am Coll Cardiol. 1998;31:841–847
  5. Legalery P, Schiele F, Seronde MF, Meneveau N, Wei H, Didier K, et al. One-year outcome of patients submitted to routine fractional flow reserve assessment to determine the need for angioplasty. Eur Heart J. 2005;26:2623–2629
  6. Potvin JM, Rodés-Cabau J, Bertrand OF, Gleeton O, Nguyen CN, Barbeau G, et al Usefulness of fractional flow reserve measurements in patients with stable or unstable angina pectoris, non–ST-elevation and ST-elevation acute myocardial infarction or atypical chest pain. Am J Cardiol. 2006;98:289–297
  7. Pijls NH, van Schaardenburgh P, Manoharan G, Boersma E, Bech JW, van't Veer M, et al. Percutaneous coronary intervention of functionally nonsignificant stenosis: 5-year follow-up of the DEFER study. J Am Coll Cardiol. 2007;42:2105–2111
  8. Bech GJ, Droste H, Pijls NH, De Bruyne B, Bonnier JJRM, Michels HR, et al. Value of fractional flow reserve in making decisions about bypass surgery for equivocal left main coronary artery disease. Heart. 2001;86:547–552
  9. Lindstaedt M, Yazar A, Germing A, Fritz MK, Holland-Letz T, Mügge A, et al. Clinical outcome in patients with intermediate or equivocal left main coronary artery disease after deferral of surgical revascularization on the basis of fractional flow reserve measurements. Am Heart J. 2006;152:156.e1–156.e9
  10. Jiménez-Navarro M, Hernandez-Garcia JM, Alonso-Briales JH, Kühlmorgen B, Gomez-Doblas JJ, Garcia-Pinilla JM, et al. Should we treat patients with moderately severe stenosis of the left main coronary artery and negative FFR results?. J Inv Cardiol. 2004;16:398–400
  11. Jasti V, Ivan E, Yalamanchili V, Wongrpraparut N, Leesar MA. Correlations between fractional flow reserve and intravascular ultrasound in patients with an ambiguous left main coronary artery stenosis. Circulation. 2004;110:2831–2836
  12. Jeremias A, Whitbourn RJ, Filardo SD, Fitzgerald PJ, Cohen DJ, Tuzcu EM, et al. Adequacy of intracoronary versus intravenous adenosine-induced maximal hyperemia for fractional flow reserve measurements. Am Heart J. 2000;140:651–657
  13. Kern MJ, Lerman A, Bech JW, De Bruyne B, Eeckhout E, Fearon WF, et al Physiological assessment of coronary artery disease in the cardiac catheterization laboratory: a scientific statement from the American Heart Association Committee on Diagnostic and Interventional Cardiac Catheterization, Council on Clinical Cardiology. Circulation. 2006;114:1321–1341
  14. Casella G, Leibig M, Schiele T, Schrepf R, Seelig V, Stempfle HU, et al. Are high doses of intracoronary adenosine an alternative to standard intravenous adenosine for the assessment of fractional flow reserve?. Am Heart J. 2004;148:590–595
  15. Courtis J, Rodés-Cabau J, Larose E, Déry JP, Nguyen CM, Proulx G, et al. Comparison of medical treatment and coronary revascularization in patients with moderate coronary lesions and borderline fractional flow reserve measurements. Catheter Cardiovasc Intervent. 2008;71:541–548
  16. Abizaid AS, Mintz GS, Abizaid A, Mehran R, Lansky AJ, Pichard AD, et al. One-year follow-up after intravascular ultrasound assessment of moderate left main coronary artery disease in patients with ambiguous angiograms. J Am Coll Cardiol. 1999;34:707–715
  17. Nicholls SJ, Tuzcu EM, Kalidindi S, Wolski K, Moon KW, Sipahi I, et al. Effect of diabetes on progression of coronary atherosclerosis and arterial remodeling: a pooled analysis of 5 intravascular ultrasound trials. J Am Coll Cardiol. 2008;52:255–262
  18. Ahmari SA, Bunch TJ, Modesto K, Stussy V, Dichak A, Seward JB, et al. Impact of individual and cumulative coronary risk factors on coronary flow reserve assessed by dobutamine stress echocardiography. Am J Cardiol. 2008;101:1694–1699
  19. Di Carli MF, Janisse J, Grunberger G, Ager J. Role of chronic hyperglycemia in the pathogenesis of coronary microvascular dysfunction in diabetes. J Am Coll Cardiol. 2003;41:1387–1393
  20. Lopez-Palop R, Saura D, Pinar E, Lozano I, Pérez-Lorente F, Pico F, et al. Adequate intracoronary adenosine doses to achieve maximal hyperemia in coronary functional studies by pressure derived fractional flow reserve: a dose response study. Heart. 2004;90:95–96

PII: S0002-9149(08)02179-6

doi: 10.1016/j.amjcard.2008.11.054

American Journal of Cardiology
Volume 103, Issue 7 , Pages 943-949 , 1 April 2009

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