American Journal of Cardiology
Volume 103, Issue 6 , Pages 845-851 , 15 March 2009

Comparison of Ventricular Structure and Function in Chinese Patients With Heart Failure and Ejection Fractions >55% Versus 40% to 55% Versus <40%

  • Kun-Lun He, MD, PhD

      Affiliations

    • Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, China
    • Corresponding Author InformationCorresponding author: Tel: +8610-66939685; fax: 8610-68152720
  • ,
  • Daniel Burkhoff, MD, PhD

      Affiliations

    • Columbia University Medical Center, New York, New York
  • ,
  • Wen-Xiu Leng, MD

      Affiliations

    • Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, China
  • ,
  • Zhi-Ru Liang, MD

      Affiliations

    • Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, China
  • ,
  • Li Fan, MD

      Affiliations

    • Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, China
  • ,
  • Jie Wang, MD, PhD

      Affiliations

    • Columbia University Medical Center, New York, New York
  • ,
  • Mathew S. Maurer, MD

      Affiliations

    • Clinical Cardiovascular Research Laboratory for the Elderly, Allen Pavilion of New York–Presbyterian Hospital, New York, New York
    • Columbia University Medical Center, New York, New York

Received 2 September 2008 ,Revised 13 November 2008 ,Accepted 13 November 2008.

References 

  1. Lloyd-Jones DM, Larson MG, Leip EP, Beiser A, D'Agostino RB, Kannel WB, et al. Lifetime risk for developing congestive heart failure: the Framingham Heart Study. Circulation. 2002;106:3068–3072
  2. Paulus WJ, Tschope C, Sanderson JE, Rusconi C, Flachskampf FA, Rademakers FE, et al How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology. Eur Heart J. 2007;28:2539–2550
  3. Maron BJ. Hypertrophic cardiomyopathy: a systematic review. JAMA. 2002;287:1308–1320
  4. Maron BJ, Spirito P, Roman MJ, Paranicas M, Okin PM, Best LG, et al. Prevalence of hypertrophic cardiomyopathy in a population-based sample of American Indians aged 51 to 77 years (the Strong Heart Study). Am J Cardiol. 2004;93:1510–1514
  5. Schiller NB, Shah PM, Crawford M, DeMaria A, Devereux R, Feigenbaum H, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography (American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms). J Am Soc Echocardiogr. 1989;2:358–367
  6. Devereux RB, Reichek N. Echocardiographic determination of left ventricular mass in man (Anatomic validation of the method). Circulation. 1977;55:613–618
  7. Ommen SR, Nishimura RA, Appleton CP, Miller FA, Oh JK, Redfield MM, et al. Clinical utility of Doppler echocardiography and tissue Doppler imaging in the estimation of left ventricular filling pressures: a comparative simultaneous Doppler-catheterization study. Circulation. 2000;102:1788–1794
  8. Lam CS, Roger VL, Rodeheffer RJ, Bursi F, Borlaug BA, Ommen SR, et al. Cardiac structure and ventricular–vascular function in persons with heart failure and preserved ejection fraction from Olmsted County, Minnesota. Circulation. 2007;115:1982–1990
  9. Chen CH, Fetics B, Nevo E, Rochitte CE, Chiou KR, Ding PA, et al. Noninvasive single-beat determination of left ventricular end-systolic elastance in humans. J Am Coll Cardiol. 2001;38:2028–2034
  10. Klotz S, Hay I, Dickstein ML, Yi GH, Wang J, Maurer MS, et al. Single-beat estimation of end-diastolic pressure–volume relationship: a novel method with potential for noninvasive application. Am J Physiol Heart Circ Physiol. 2006;291:H403–H412
  11. Burkhoff D, Mirsky I, Suga H. Assessment of systolic and diastolic ventricular properties via pressure–volume analysis: a guide for clinical, translational, and basic researchers. Am J Physiol Heart Circ Physiol. 2005;289:H501–H512
  12. Sunagawa K, Maughan WL, Burkhoff D, Sagawa K. Left ventricular interaction with arterial load studied in isolated canine ventricle. Am J Physiol Heart Circ Physiol. 1983;245:H773–H780
  13. Kelly RP, Ting CT, Yang TM, Liu CP, Maughan WL, Chang MS, et al. Effective arterial elastance as index of arterial vascular load in humans. Circulation. 1992;86:513–521
  14. Sweitzer NK, Lopatin M, Yancy CW, Mills RM, Stevenson LW. Comparison of clinical features and outcomes of patients hospitalized with heart failure and normal ejection fraction (>/=55%) versus those with mildly reduced (40% to 55%) and moderately to severely reduced (<40%) fractions. Am J Cardiol. 2008;101:1151–1156
  15. Maisel AS, McCord J, Nowak RM, Hollander JE, Wu AH, Duc P, et al Bedside B-Type natriuretic peptide in the emergency diagnosis of heart failure with reduced or preserved ejection fraction (Results from the Breathing Not Properly Multinational Study). J Am Coll Cardiol. 2003;41:2010–2017
  16. Vinch CS, Aurigemma GP, Hill JC, Gaasch WH, Volturo G, Tighe DA, et al. Usefulness of clinical variables, echocardiography, and levels of brain natriuretic peptide and norepinephrine to distinguish systolic and diastolic causes of acute heart failure. Am J Cardiol. 2003;91:1140–1143
  17. De Keulenaer GW, Brutsaert DL. Systolic and diastolic heart failure: different phenotypes of the same disease?. Eur J Heart Fail. 2007;9:136–143
  18. De Keulenaer GW, Brutsaert DL. Diastolic heart failure: a separate disease or selection bias?. Prog Cardiovasc Dis. 2007;49:275–283
  19. Yu CM, Lin H, Yang H, Kong SL, Zhang Q, Lee SW. Progression of systolic abnormalities in patients with “isolated” diastolic heart failure and diastolic dysfunction. Circulation. 2002;105:1195–1201
  20. Sanderson JE. Diastolic heart failure or heart failure with a normal ejection fraction. Minerva Cardioangiol. 2006;54:715–724
  21. Sanderson JE. Heart failure with a normal ejection fraction. Heart. 2007;93:155–158
  22. Sanderson JE. Systolic and diastolic ventricular dyssynchrony in systolic and diastolic heart failure. J Am Coll Cardiol. 2007;49:106–108
  23. Yu CM, Sanderson JE, Marwick TH, Oh JK. Tissue Doppler imaging a new prognosticator for cardiovascular diseases. J Am Coll Cardiol. 2007;49:1903–1914
  24. Klotz S, Hay I, Zhang G, Maurer M, Wang J, Burkhoff D. Development of heart failure in chronic hypertensive Dahl rats: focus on heart failure with preserved ejection fraction. Hypertension. 2006;47:901–911
  25. Felker GM, Thompson RE, Hare JM, Hruban RH, Clemetson DE, Howard DL, et al. Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy. N Engl J Med. 2000;342:1077–1084
  26. Yusuf S, Pfeffer MA, Swedberg K, Granger CB, Held P, McMurray JJ, et al. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial. Lancet. 2003;362:777–781
  27. Ahmed A, Rich MW, Fleg JL, Zile MR, Young JB, Kitzman DW, et al. Effects of digoxin on morbidity and mortality in diastolic heart failure: the ancillary digitalis investigation group trial. Circulation. 2006;114:397–403
  28. Cleland JG, Tendera M, Adamus J, Freemantle N, Polonski L, Taylor J. The perindopril in elderly people with chronic heart failure (PEP-CHF) study. Eur Heart J. 2006;27:2338–2345
  29. McMurray JJ, Carson PE, Komajda M, McKelvie R, Zile MR, Ptaszynska A, et al. Heart failure with preserved ejection fraction: clinical characteristics of 4133 patients enrolled in the I-PRESERVE trial. Eur J Heart Fail. 2008;10:149–156
  30. Aldosterone antagonist therapy for adults with heart failure and preserved systolic function (TOPCAT). http://clinicaltrials.gov/ct2/show/NCT00094302?term=topcat&rank=12008;Last accessed January 24, 2009

 This work is supported by Grants 2007AA02Z4B7 and 2006DFB32210 from the Ministry of Science and Technology of China, Beijing, China and by Grant 7052063 from the Beijing Natural Science Foundation, Beijing, China. Dr. Maurer was supported by Grant R01AG027518-01A1 from the National Institutes of Health/National Institute on Aging, Bethesda, Maryland.

PII: S0002-9149(08)02118-8

doi: 10.1016/j.amjcard.2008.11.050

American Journal of Cardiology
Volume 103, Issue 6 , Pages 845-851 , 15 March 2009