American Journal of Cardiology
Volume 103, Issue 3, Supplement , Pages 20A-26A , 2 February 2009

Methods for the Measurement of Platelet Function

  • Alan D. Michelson, MD

      Affiliations

    • Corresponding Author InformationAddress for reprints: Alan D. Michelson, MD, Center for Platelet Function Studies, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655

References 

  1. Brass LF, Stalker TJ, Zhou L, Woulfe DS. Signal transduction during platelet plug formation. In:  Michelson AD editors. Platelets. 2nd ed.. San Diego: Elsevier/Academic Press; 2007;p. 329–346
  2. Awtry EH, Loscalzo J. Aspirin. In:  Michelson AD editors. Platelets. 2nd ed.. San Diego: Elsevier/Academic Press; 2007;p. 1099–1125
  3. Frelinger AL, Furman MI, Linden MD, Li Y, Fox ML, Barnard MR, et al. Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance. Circulation. 2006;113:2888–2896
  4. Cattaneo M. ADP receptor antagonists. In:  Michelson AD editors. Platelets. 2nd ed.. San Diego: Elsevier/Academic Press; 2007;p. 1127–1144
  5. Agah R, Plow EF, Topol EJ. αIIbβ3 (GPIIb-IIIa) antagonists. In:  Michelson AD editors. Platelets. 2nd ed.. San Diego: Elsevier/Academic Press; 2007;p. 1145–1163
  6. Harrison P, Keeling D. Clinical tests of platelet function. In:  Michelson AD editors. Platelets. 2nd ed.. San Diego: Elsevier/Academic Press; 2007;p. 445–474
  7. Michelson AD. Platelet function testing in cardiovascular diseases. Circulation. 2004;110:e489–e493
  8. Born GVR. Aggregation of blood platelets by adenosine diphosphate and its reversal. Nature. 1962;194:927–929
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  10. Jennings LK, White MM. Platelet aggregation. In:  Michelson AD editors. Platelets. 2nd ed.. San Diego: Elsevier/Academic Press; 2007;p. 495–508
  11. Steinhubl SR. The VerifyNow system. In:  Michelson AD editors. Platelets. 2nd ed.. San Diego: Elsevier/Academic Press; 2007;p. 509–518
  12. Michelson AD, Linden MD, Barnard MR, Furman MI, Frelinger AL. Flow cytometry. In:  Michelson AD editors. Platelets. 2nd ed.. San Diego: Elsevier/Academic Press; 2007;p. 545–564
  13. Shattil SJ, Hoxie JA, Cunningham M, Brass LF. Changes in the platelet membrane glycoprotein IIb-IIIa complex during platelet activation. J Biol Chem. 1985;260:11107–11114
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  15. Michelson AD, Barnard MR, Krueger LA, Valeri CR, Furman MI. Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: studies in baboons, human coronary intervention, and human acute myocardial infarction. Circulation. 2001;104:1533–1537
  16. Wiviott SD, Trenk D, Frelinger AL, O'Donoghue M, Neumann FJ, Michelson AD, et al Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial. Circulation. 2007;116:2923–2932
  17. Bouchard BA, Butenas S, Mann KG, Tracy PB. Interactions between platelets and the coagulation system. In:  Michelson AD editors. Platelets. 2nd ed.. San Diego: Elsevier/Academic Press; 2007;p. 377–402
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  28. Michelson AD, Frelinger AL, Furman MI. Resistance to antiplatelet drugs. Eur Heart J. 2006;8:G53–G58
  29. Gurbel PA, Bliden KP, DiChiara J, Newcomer J, Weng W, Neerchal NK, et al. Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study. Circulation. 2007;115:3156–3164
  30. Chen WH, Lee PY, Ng W, Tse HF, Lau CP. Aspirin resistance is associated with a high incidence of myonecrosis after non-urgent percutaneous coronary intervention despite clopidogrel pretreatment. J Am Coll Cardiol. 2004;43:1122–1126
  31. Crescente M, Di Castelnuovo A, Iacoviello L, Vermylen J, Cerletti C, de Gaetano G. Response variability to aspirin as assessed by the platelet function analyzer (PFA)-100: a systematic review. Thromb Haemost. 2008;99:14–26
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  33. Jennings LK, White MM. Expression of ligand-induced binding sites on glycoprotein IIb/IIIa complexes and the effect of various inhibitors. Am Heart J. 1998;135:S179–S183

 Statement of author disclosure: Please see the Author Disclosures section at the end of this article.

PII: S0002-9149(08)02029-8

doi: 10.1016/j.amjcard.2008.11.019

American Journal of Cardiology
Volume 103, Issue 3, Supplement , Pages 20A-26A , 2 February 2009

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