American Journal of Cardiology
Volume 102, Issue 7 , Pages 831-834 , 1 October 2008

Usefulness of Fasting Plasma Glucose to Predict Mortality or Coronary Heart Disease in Persons ≥60 Years of Age Without Diabetes Mellitus or in Those With Undiagnosed Diabetes Mellitus (from The Dubbo Study)

  • Leon A. Simons, MD, PhD

      Affiliations

    • University of NSW Lipid Research Department, St. Vincent's Hospital, Sydney NSW Australia
    • Corresponding Author InformationCorresponding author: Tel: +61-2-8382 2301; fax: +61-2-9327 4374
    • ,
  • Judith Simons, MACS

      Affiliations

    • University of NSW Lipid Research Department, St. Vincent's Hospital, Sydney NSW Australia
    • ,
  • Yechiel Friedlander, PhD

      Affiliations

    • Epidemiology Unit, Hebrew University, Hadassah School of Public Health, Jerusalem Israel
    • ,
  • John McCallum, DPhil

      Affiliations

    • Vice-Chancellor's Department, Victoria University, Melbourne Victoria, Australia

Received 3 March 2008 ,Revised 4 May 2008 ,Accepted 4 May 2008.

References 

  1. Ford ES, de Stefano F. Risk factors for mortality from all-causes and from coronary heart disease among persons with diabetes: Findings from the National Health & Nutrition Examination Survey I Epidemiologic Follow-Up Study. Am J Epidemiol. 1991;133:1220–1230
  2. Knuiman MW, Welborn TA, Wittall DE. An analysis of excess mortality rates for persons with non-insulin dependent diabetes mellitus in Western Australia using the Cox proportional hazards regression model. Am J Epidemiol. 1992;135:638–648
  3. Stamler J, Wentworth D, Vaccaro O, Neaton JD. Diabetes, other risk factors and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care. 1993;16:434–444
  4. Simons LA, McCallum J, Friedlander Y, Simons J. Diabetes, mortality and coronary heart disease in the prospective Dubbo Study of Australian elderly. Aust New Zeal J Med. 1996;26:66–74
  5. Coutinho M, Gerstein HC, Wang Y, Yusuf S. The relationship between glucose and incident cardiovascular events (A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years). Diabetes Care. 1999;22:233–240
  6. Levitan EB, Song Y, Ford ES, Liu S. Is nondiabetic hyperglycemia a risk factor for cardiovascular disease? (A meta-analysis of prospective studies). Arch Intern Med. 2004;164:2147–2155
  7. Smith NL, Barzilay JI, Shaffer D, Savage PJ, Heckbert SR, Kuller LH, et al. Fasting and 2-hour post challenge serum glucose measures and risk of incident cardiovascular events in the elderly. Arch Intern Med. 2002;162:209–216
  8. Eguchi K, Boden-Albala B, Jin Z, Di Tullio MR, Rundek T, Rodriguez CJ, et al. Usefulness of fasting blood glucose to predict vascular outcomes among individuals without diabetes mellitus (from the Northern Manhattan Study). Am J Cardiol. 2007;100:1404–1409
  9. Levitzky YS, Pencina MJ, D'Agostino RB, Meigs JB, Murabito JM, Vasan RS, et al. Impact of impaired fasting glucose on cardiovascular disease (The Framingham Heart Study). J Am Coll Cardiol. 2008;51:264–270
  10. Simons LA, McCallum J, Friedlander Y, Simons J, Powell I, Heller R. Dubbo Study of the elderly: sociological and cardiovascular risk factors at entry. Aust New Zeal J Med. 1991;21:701–709
  11. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 1997;20:1183–1201
  12. Pankow JS, Kwan DK, Duncan BB, Schmidt MI, Couper DJ, Golden S, et al. Cardiometabolic risk in impaired fasting glucose and impaired glucose tolerance. Diabetes Care. 2007;30:325–331
  13. Park S, Barrett-Connor E, Wingard D, Shan J, Edelstein S. GHb is a better predictor of cardiovascular disease than fasting or postchallenge plasma glucose in women without diabetes: the Rancho Bernardo Study. Diabetes Care. 1996;19:450–456
  14. The DECODE Study Group. Glucose tolerance and cardiovascular mortality (Comparison of fasting and 2-hour diagnostic criteria). Arch Intern Med. 2001;161:397–404
  15. Gerich JE. Clinical significance, pathogenesis, and management of postprandial hyperglycemia. Arch Intern Med. 2003;163:1306–1316
  16. King GL, Wakasaki H. Theoretical mechanisms by which hyperglycemia and insulin resistance could cause cardiovascular diseases in diabetes. Diabetes Care. 1999;22(suppl 3):C31–C37

 The Dubbo Study has received past support from the Australian Research Council and the National Health and Medical Research Council of Australia.

PII: S0002-9149(08)00914-4

doi: 10.1016/j.amjcard.2008.05.030

American Journal of Cardiology
Volume 102, Issue 7 , Pages 831-834 , 1 October 2008

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