American Journal of Cardiology
Volume 102, Issue 6 , Pages 738-742 , 15 September 2008

Stage-Related Effect of Statin Treatment on the Progression of Aortic Valve Sclerosis and Stenosis

  • Francesco Antonini-Canterin, MD

      Affiliations

    • Cardiologia Association for Research in Cardiology, Azienda Ospedaliera “S. Maria degli Angeli,” Pordenone, Italy
    • Corresponding Author InformationCorresponding author: Tel: 39-0434-399-462; fax: 39-0434-399-197
    • ,
  • Monica Hîrşu, MD

      Affiliations

    • “Prof. Dr. C. C. Iliescu” Institute of Cardiovascular Diseases, Bucharest, Romania
    • ,
  • Bogdan Alexandru Popescu, MD, PhD

      Affiliations

    • “Prof. Dr. C. C. Iliescu” Institute of Cardiovascular Diseases, Bucharest, Romania
    • ,
  • Elisa Leiballi, MD

      Affiliations

    • Cardiologia Association for Research in Cardiology, Azienda Ospedaliera “S. Maria degli Angeli,” Pordenone, Italy
    • ,
  • Rita Piazza, MD

      Affiliations

    • Cardiologia Association for Research in Cardiology, Azienda Ospedaliera “S. Maria degli Angeli,” Pordenone, Italy
    • ,
  • Daniela Pavan, MD

      Affiliations

    • Cardiologia Association for Research in Cardiology, Azienda Ospedaliera “S. Maria degli Angeli,” Pordenone, Italy
    • ,
  • Carmen Ginghină, MD, PhD

      Affiliations

    • “Prof. Dr. C. C. Iliescu” Institute of Cardiovascular Diseases, Bucharest, Romania
    • ,
  • Gian Luigi Nicolosi, MD

      Affiliations

    • Cardiologia Association for Research in Cardiology, Azienda Ospedaliera “S. Maria degli Angeli,” Pordenone, Italy

Received 7 March 2008 ,Revised 29 April 2008 ,Accepted 29 April 2008.

References 

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  16. Chan KL, Teo K, Tam J, Dumesnil JG. Rationale, design, and baseline characteristics of a randomized trial to assess the effect of cholesterol lowering on the progression of aortic stenosis: The Aortic Stenosis Progression Observation: Measuring Effects of Rosuvastatin (ASTRONOMER) trial. Am Heart J. 2007;153:925–931
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  19. Goldbarg SH, Elmariah S, Miller MA, Fuster V. Insights into degenerative aortic valve disease. J Am Coll Cardiol. 2007;50:1205–1213
  20. Otto CM, O'Brien KD. Why is there discordance between calcific aortic stenosis and coronary artery disease?. Heart. 2001;85:601–602
  21. Otto CM, Lind BK, Kitzman DW, Gersh BJ, Siscovick DS. Association of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly. N Engl J Med. 1999;341:142–147

 Drs. Monica Hîrşu and Bogdan A. Popescu were supported by research grants from the Association for Research in Cardiology, Pordenone, Italy.

PII: S0002-9149(08)00847-3

doi: 10.1016/j.amjcard.2008.04.056

American Journal of Cardiology
Volume 102, Issue 6 , Pages 738-742 , 15 September 2008

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