American Journal of Cardiology
Volume 102, Issue 6 , Pages 679-682 , 15 September 2008

Safety of Drug-Eluting Stents in Patients With Left Ventricular Dysfunction Undergoing Percutaneous Coronary Intervention

  • Annunziata Nusca, MD

      Affiliations

    • VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia
    • Department of Cardiovascular Sciences, University Campus Bio-Medico, Rome, Italy
    • ,
  • Michael J. Lipinski, MD

      Affiliations

    • Department of Internal Medicine, University of Virginia, Charlottesville, Virginia
    • ,
  • Amit Varma, MD

      Affiliations

    • VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • Darryn L. Appleton, MBChB

      Affiliations

    • VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • Evelyne Goudreau, MD

      Affiliations

    • VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • Michael J. Cowley, MD

      Affiliations

    • VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • Michael J. Wittkamp, MD

      Affiliations

    • VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • Germano Di Sciascio, MD

      Affiliations

    • Department of Cardiovascular Sciences, University Campus Bio-Medico, Rome, Italy
    • ,
  • George W. Vetrovec, MD

      Affiliations

    • VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • Antonio Abbate, MD

      Affiliations

    • VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia
    • Corresponding Author InformationCorresponding author: Tel: 804-270-2946; fax: 360-323-1204

Received 3 April 2008 ,Revised 29 April 2008 ,Accepted 29 April 2008.

References 

  1. Iakovou I, Schmidt T, Bonizzoni E, Ge L, Sangiorgi GM, Stankovic G, et al Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents. JAMA. 2005;293:2126–2130
  2. Moussa I, Di Mario C, Reimers B, Akiyama T, Tobis J, Colombo A. Subacute stent thrombosis in the era of intravascular ultrasound-guided coronary stenting without anticoagulation: frequency, predictors and clinical outcome. J Am Coll Cardiol. 1997;29:6–12
  3. Win HK, Caldera AE, Maresh K, Lopez J, Rihal CS, Parikh MA, et al. Clinical outcomes and stent thrombosis following off-label use of drug-eluting stents. JAMA. 2007;297:2001–2009
  4. Lipinski MJ, Martin RE, Cowley MJ, Goudreau E, Malloy WN, Vetrovec GW. Improved survival for stenting vs. balloon angioplasty for the treatment of coronary artery disease in patients with ischemic left ventricular dysfunction. Catheter Cardiovasc Interv. 2005;66:547–553
  5. Di Sciascio G, Patti G, D'Ambrosio A, Nusca A. Coronary stenting in patients with depressed left ventricular function: acute and long-term results in a selected population. Catheter Cardiovasc Interv. 2003;59:429–433
  6. Biondi-Zoccai GGL, Moretti C, Abbate A, Lipinski MJ, De Luca G, Agostoni P, et al. Percutaneous coronary stenting in patients with left ventricular systolic dysfunction: a systematic review and meta-analysis. EuroInterv. 2007;3:409–415
  7. Stone GW, Moses JW, Ellis SG, Schofer J, Dawkins KD, Morice MC, et al Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents. N Engl J Med. 2007;356:998–1008
  8. Applegate RJ, Sacrinty MT, Kutcher MA, Santos RM, Gandhi SK, Baki TT, et al. “Off-label” stent therapy 2-year comparison of drug-eluting versus bare-metal stents. J Am Coll Cardiol. 2008;51:607–614
  9. Marroquin OC, Selzer F, Mulukutla SR, Williams DO, Vlachos HA, Wilensky RL, et al A comparison of bare-metal and drug-eluting stents for off-label indications. N Engl J Med. 2008;358:342–352
  10. Gioia G, Matthai W, Benassi A, Rana H, Levite HA, Ewing LG. Improved survival with drug-eluting stent implantation in comparison with bare metal stent in patients with severe left ventricular dysfunction. Catheter Cardiovasc Interv. 2006;68:392–398
  11. Walters DL, Harding SA, Walsh CR, Wong P, Pomerantsev E, Jang IK. Acute coronary syndrome is a common clinical presentation of in-stent restenosis. Am J Cardiol. 2002;89:491–494
  12. Chen MS, John JM, Chew DP, Lee DS, Ellis SG, Bhatt DL. Bare metal stent restenosis is not a benign clinical entity. Am Heart J. 2006;151:1260–1264
  13. Bossi I, Klersy C, Black AJ, Cortina R, Choussat R, Cassagneau B, et al. In-stent restenosis: long-term outcome and predictors of subsequent target lesion revascularization after repeat balloon angioplasty. J Am Coll Cardiol. 2000;35:1569–1576
  14. Assali AR, Moustapha A, Sdringola S, Denktas AE, Willerson JT, Holmes DR, et al. Acute coronary syndrome may occur with in-stent restenosis and is associated with adverse outcomes (the PRESTO trial). Am J Cardiol. 2006;98:729–733

PII: S0002-9149(08)00836-9

doi: 10.1016/j.amjcard.2008.04.049

American Journal of Cardiology
Volume 102, Issue 6 , Pages 679-682 , 15 September 2008

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