Contents

Article Outline

• Coronary Artery Disease
• Roundtable Discussion
• Preventive Cardiology
• Systemic Hypertension
• Heart Failure
• Valvular Heart Disease
• Cardiomyopathy
• Congenital Heart Disease
• Miscellaneous
• Review
• Editorials
• Readers’ Comments

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Coronary Artery Disease 

Inflammatory Markers, Angiographic Severity of Coronary Artery Disease, and Patient Outcome 879

Rishi Sukhija, Ibrahim Fahdi, Luis Garza, Louis Fink, Margaret Scott, Wady Aude, Rebecca Pacheco, Zoran Bursac, April Grant, and Jawahar L. Mehta

Clinical Impact of Metabolic Syndrome and Its Additive Effect With Smoking on Subsequent Cardiac Events After Acute Myocardial Infarction 885

Daisaku Nakatani, Yasuhiko Sakata, Hiroshi Sato, Hiroya Mizuno, Masahiko Shimizu, Shinichiro Suna, Hiroshi Ito, Yukihiro Koretsune, Atsushi Hirayama, and Masatsugu Hori, on behalf of the Osaka Acute Coronary Insufficiency Study (OACIS) Group

Serum Complement C3/C4 Ratio, a Novel Marker for Recurrent Cardiovascular Events 890

Anil Palikhe, Juha Sinisalo, Mikko Seppänen, Heikki Haario, Seppo Meri, Ville Valtonen, Markku S. Nieminen, and Marja-Liisa Lokki

Comparison Between Angiography and Fractional Flow Reserve Versus Single-Photon Emission Computed Tomographic Myocardial Perfusion Imaging for Determining Lesion Significance in Patients With Multivessel Coronary Disease 896

Michael Ragosta, Andrew H. Bishop, Lewis C. Lipson, Denny D. Watson, Lawrence W. Gimple, Ian J. Sarembock, and Eric R. Powers

Effects of Atorvastatin on Vitamin D Levels in Patients With Acute Ischemic Heart Disease 903

José L. Pérez-Castrillón, Gemma Vega, Laura Abad, Alberto Sanz, José Chaves, Gonzalo Hernandez, and Antonio Dueñas

Impact of Body Mass Index on Outcomes After Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction 906

Laxmi Mehta, William Devlin, Peter A. McCullough, William W. O’Neill, Kimberly A. Skelding, Gregg W. Stone, Judith A. Boura, and Cindy L. Grines

Safety and Efficacy of the FilterWire EZ in Acute ST-Segment Elevation Myocardial Infarction 911

Victor Guetta, Morris Mosseri, Michael Shechter, Shlomi Matetzky, Abid Assali, Yaron Almagor, Luis Gruberg, Michal Benderly, Chaim Lotam, and Ran Kornowski, for the UpFlow MI Study Investigators

Frequency of Slow Coronary Flow Following Successful Stent Implantation and Effect of Nitroprusside 916

Flavio Airoldi, Carlo Briguori, Domenico Cianflone, John Cosgrave, Goran Stankovic, Cosmo Godino, Mauro Carlino, Alaide Chieffo, Matteo Montorfano, Marco Mussardo, Iassen Michev, Antonio Colombo, and Attilio Maseri

Different Thresholds of Myocardial Ischemia in Ramp and Standard Bruce Protocol Exercise Tests in Patients With Positive Exercise Stress Tests and Angiographically Demonstrated Coronary Arterial Narrowing 921

Martin Noël, Jean Jobin, Paul Poirier, Gilles R. Dagenais, and Peter Bogaty

Usefulness of 64-Slice Multidetector Computed Tomography in Diagnostic Triage of Patients With Chest Pain and Negative or Nondiagnostic Exercise Treadmill Test Result 925

Ronen Rubinshtein, David A. Halon, Tamar Gaspar, Jorge E. Schliamser, Nisan Yaniv, Ronny Ammar, Moshe Y. Flugelman, Nathan Peled, and Basil S. Lewis

Self-Reported Use of Complementary and Alternative Medicine in Patients With Previous Acute Coronary Syndrome 930

Carole Decker, Jason Huddleston, Mikhail Kosiborod, Donna M. Buchanan, Casey Stoner, Angela Jones, Sudeshna Banerjee, and John A. Spertus

Usefulness of ST Depression With T-Wave Inversion in Leads V₄ to V₆ for Predicting One-Year Mortality in Non–ST-Elevation Acute Coronary Syndrome (from the Electrocardiographic Analysis of the Global Use of Strategies to Open Occluded Coronary Arteries IIB Trial) 934

Shaul Atar, Yuling Fu, Galen S. Wagner, Salvatore Rosanio, Alejandro Barbagelata, and Yochai Birnbaum

Prognostic Value of Transient and Sustained Increase in In-Hospital Creatinine on Outcomes of Patients Admitted With Acute Coronary Syndrome 939

Rakesh Latchamsetty, Jianming Fang, Eva Kline-Rogers, Debabrata Mukherjee, Richard F. Otten, Troy M. LaBounty, Michael S. Emery, Kim A. Eagle, and James B. Froehlich

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Roundtable Discussion 

The Editor’s Roundtable: Intravascular Ultrasonic Imaging of the Coronary Arteries 943

Vincent E. Friedewald, Steven P. Marso, E. Murat Tuzcu, Neil J. Weissman, and William C. Roberts

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Preventive Cardiology 

Value of Electrocardiographic and Ankle–Brachial Index Abnormalities for Prediction of Coronary Atherosclerosis in Asymptomatic Subjects With Type 2 Diabetes Mellitus 951

Roshanak Bagheri, Mark Schutta, Reshmaal Gomes Cumaranatunge, Megan L. Wolfe, Karen Terembula, Barry Hoffman, Stan Schwartz, Stephen E. Kimmel, Samira Farouk, Nayyar Iqbal, and Muredach P. Reilly

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Systemic Hypertension 

Effect of Antihypertensive Therapy on Progression of Carotid Intima-Media Thickness in Patients With Type 2 Diabetes Mellitus 956

Ling Zheng, Howard N. Hodis, Thomas A. Buchanan, Yanjie Li, and Wendy J. Mack

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Heart Failure 

Usefulness of Right Ventricular Tissue Doppler Imaging to Predict Outcome in Left Ventricular Heart Failure Independent of Left Ventricular Diastolic Function 961

Hisham Dokainish, Ranjita Sengupta, Rajnikant Patel, and Nasser Lakkis

Qualitative Observation of Left Ventricular Multiphasic Septal Motion and Septal-to-Lateral Apical Shuffle Predicts Left Ventricular Reverse Remodeling After Cardiac Resynchronization Therapy 966

Annemieke H.M. Jansen, Jan melle van Dantzig, Franck Bracke, Albert Meijer, Kathinka H. Peels, Renee B.A. van den Brink, Emile C. Cheriex, Ben J.M. Delemarre, Pol A. van der Wouw, Hendrikus H.M. Korsten, and Norbert M. van Hemel

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Valvular Heart Disease 

Design and Baseline Characteristics of the Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) Study 970

Anne B. Rossebø, Terje R. Pedersen, Christopher Allen, Kurt Boman, John Chambers, Kenneth Egstrup, Eva Gerdts, Christa Gohlke-Bärwolf, Ingar Holme, V. Antero Y. Kesäniemi, William Malbecq, Christoph Nienaber, Simon Ray, Terje Skjærpe, Kristian Wachtell, and Ronnie Willenheimer

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Cardiomyopathy 

Acute Cardiac Functional and Morphological Changes After Anthracycline Infusions in Children 974

Javier Ganame, Piet Claus, Benedicte Eyskens, Anne Uyttebroeck, Marleen Renard, Jan D’hooge, Marc Gewillig, Bart Bijnens, George R. Sutherland, and Luc Mertens

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Congenital Heart Disease 

Progressive Dilation of the Ascending Aorta in Children With Isolated Bicuspid Aortic Valve 978

Kathryn W. Holmes, Christoph U. Lehmann, Darshan Dalal, Khuram Nasir, Harry C. Dietz, William J. Ravekes, W. Reid Thompson, and Philip J. Spevak

Transcatheter Closure of Perimembranous Ventricular Septal Defects in Infants and Children Using the Amplatzer Perimembranous Ventricular Septal Defect Occluder 984

Basil (Vasilios) D. Thanopoulos, Michael L. Rigby, Evangelos Karanasios, Christodoulos Stefanadis, Nico Blom, Jaap Ottenkamp, and Armine Zarayelyan

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Miscellaneous 

Frequency and Extent of Media in the Internal Carotid Artery in “Endarterectomy” Specimens 990

William Clifford Roberts, Nolan Joseph Laborde, and Gregory John Pearl

Assessment of Fetal Myocardial Performance Using Myocardial Deformation Analysis 993

Zeev Perles, Amiram Nir, Sagui Gavri, and Azaria J.J.T. Rein

Usefulness of an Abnormal Cardiovascular Response During Low-Grade Head-Up Tilt-Test for Discriminating Adolescents With Chronic Fatigue from Healthy Controls 997

Vegard Bruun Wyller, Reidar Due, J. Philip Saul, Jan P. Amlie, and Erik Thaulow

Impact of Smart Infusion Technology on Administration of Anticoagulants (Unfractionated Heparin, Argatroban, Lepirudin, and Bivalirudin) 1002

John Fanikos, Karen Fiumara, Steve Baroletti, Carol Luppi, Catherine Saniuk, Amar Mehta, Jon Silverman, and Samuel Z. Goldhaber

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Review 

Effect of Inhibition of the Renin-Angiotensin System on Development of Type 2 Diabetes Mellitus (Meta-Analysis of Randomized Trials) 1006

Richard Andraws and David L. Brown

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Editorials 

The Things to Come of SHAPE: Cost and Effectiveness of Cardiovascular Prevention 1013

George A. Diamond and Sanjay Kaul

Assessing Prognosis in Patients With Diabetes Mellitus—The Achilles’ Heel of Cardiac Stress Imaging Tests? 1016

Masoor Kamalesh, Harvey Feigenbaum, and Stephen Sawada

Late Stent Thrombosis: Problem or Not? 1020

John Somberg and Judah Weinberger

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Readers’ Comments 

The Triangle of Valve Calcification—Cytokine—Bone Resorption: Propose of Novel Potential Pathophysiologic Link 1024

Predictors of Left Ventricular Remodeling After Reperfused Acute Myocardial Infarction 1024

Selective Serotonin Reuptake Inhibitors May Interfere With the Antiplatelet Effect of Clopidogrel 1025

Instructions to Authors can be found at the AJC website: www.AJConline.org

Classifieds on pages A17–A18