American Journal of Cardiology
Volume 99, Issue 9 , Pages 1208-1211 , 1 May 2007

Prognostic Impact of Acute Beta-Blocker Therapy on Top of Aspirin and Angiotensin-Converting Enzyme Inhibitor Therapy in Consecutive Patients With ST-Elevation Acute Myocardial Infarction

  • Harm Wienbergen, MD

      Affiliations

    • Corresponding Author InformationCorresponding author: Tel: 01149-621-503-4000; fax: 01149-621-503-4044.
    • ,
  • Uwe Zeymer, MD
    • ,
  • Anselm Kai Gitt, MD
    • ,
  • Claus Juenger, MD, MPH
    • ,
  • Rudolf Schiele, MD
    • ,
  • Tobias Heer, MD
    • ,
  • Frank Towae, MD
    • ,
  • Jochen Senges, MD
    • ,
  • MITRA PLUS Study Group

      Affiliations

    • The MITRA PLUS study was supported by the Landesversicherungsanstalt, Rheinland Pfalz, Germany; the Ministerium für Arbeit, Soziales und Gesundheit, Rheinland-Pfalz, Germany; MSD Sharp & Dohme, Haar, Germany; Bristol-Myers Squibb, München, Germany; Aventis Pharma, Bad Soden, Germany; AstraZeneca, Wedel, Germany; Pfizer, Karlsruhe, Germany; and Abbott, Ludwigshafen, Germany.

Received 13 September 2006 ,Revised 7 December 2006 ,Accepted 7 December 2006.

References 

  1. Antman EM, Anbe DT, Armstrong PW, Bates ER, Green LA, Hand M, et al ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction. J Am Coll Cardiol. 2004;44:671–719
  2. Yusuf S, Lessem J, Jha P, Lonn E. Primary and secondary prevention of myocardial infarction and strokes: an update of randomly allocated, controlled trials. J Hypertens. 1993;11(suppl):S61–S73
  3. First International Study of Infarct Survival Collaborative Group. Randomised trial of intravenous atenolol among 16 027 cases of suspected acute myocardial infarction: ISIS-1. Lancet. 1986;2:57–66
  4. Harjai KJ, Stone GW, Boura J, Grines L, Garcia E, Brodie B, et al. Effects of prior beta-blocker therapy on clinical outcomes after primary coronary angioplasty for acute myocardial infarction. Am J Cardiol. 2003;91:655–660
  5. Pfisterer M, Cox JL, Granger CB, Brener SJ, Naylor CD, Califf RM, et al. Atenolol use and clinical outcomes after thrombolysis for acute myocardial infarction: the GUSTO-I experience (Global Utilization of Streptokinase and TPA (alteplase) for Occluded Coronary Arteries). J Am Coll Cardiol. 1998;32:634–640
  6. Freemantle N, Cleland J, Young P, Mason J, Harrison J. β-Blockade after myocardial infarction: systematic review and meta regression analysis. BMJ. 1999;318:1730–1737
  7. Second Chinese Cardiac Study (CCS-2) Collaborative Group. Rationale, design and organization of the Second Chinese Cardiac Study (CCS-2): a randomized trial of clopidogrel plus aspirin, and of metoprolol, among patients with suspected acute myocardial infarction. J Cardiovasc Risk. 2000;7:435–441
  8. COMMIT (Clopidogrel and Metoprolol In Myocardial Infarction Trial) Collaborative Group. Early intravenous then oral metoprolol in 45852 patients with acute myocardial infarction: randomised placebo-controlled trial. Lancet. 2005;366:1622–1632
  9. Rustige J, Schiele R, Burczyk U, Koch A, Gottwik M, Neuhaus KL, et al. The 60 minutes myocardial infarction project (Treatment and clinical outcome of patients with acute myocardial infarction in Germany). Eur Heart J. 1997;18:1438–1446
  10. Schuster S, Koch A, Burczyk U, Schiele R, Wagner S, Zahn R, et al Therapy of acute myocardial infarction, impact of clinical trials on clinical practice: the MITRA pilot phase. Z Kardiol. 1997;86:273–283
  11. Wagner S, Schneider S, Schiele R, Fischer F, Dehn H, Grube R, et al. Acute myocardial infarction in Germany between 1996 and 1998; therapy and intrahospital course: results of the Myocardial Infarction Registry (MIR) in Germany. Z Kardiol. 1999;88:857–867
  12. Wienbergen H, Gitt AK, Schiele R, Juenger C, Heer T, Gottwik M, et al. Actual clinical practice of exercise testing in consecutive patients after non–ST-elevation myocardial infarction: results of the Acute Coronary Syndromes Registry. Eur J Cardiovasc Prev Rehabil. 2006;13:457–463
  13. Morrow DA, Antman EM, Charlesworth A, Cairns R, Murphy SA, de Lemos JA, et al. TIMI risk score for ST-elevation myocardial infarction: a convenient, bedside, clinical score for risk assessment at presentation. Circulation. 2000;102:2031–2037
  14. Owen A. Intravenous beta-blockade in acute myocardial infarction (Should be used in combination with thrombolysis). BMJ. 1998;317:226–227

PII: S0002-9149(07)00147-6

doi: 10.1016/j.amjcard.2006.12.036

American Journal of Cardiology
Volume 99, Issue 9 , Pages 1208-1211 , 1 May 2007

Article Tools

* Image Usage & Resolution