American Journal of Cardiology
Volume 99, Issue 9 , Pages 1183-1186 , 1 May 2007

Presence and Severity of Noncalcified Coronary Plaque on 64-Slice Computed Tomographic Coronary Angiography in Patients With Zero and Low Coronary Artery Calcium

  • Victor Y. Cheng, MD

      Affiliations

    • Division of Cardiology, Beverly Hills, California
    • ,
  • Norman E. Lepor, MD

      Affiliations

    • Division of Cardiology, Beverly Hills, California
    • Westside Medical Imaging, Beverly Hills, California.
    • Corresponding Author InformationCorresponding author: Tel: 310-289-9955; fax: 310-289-9959.
    • ,
  • Hooman Madyoon, MD

      Affiliations

    • Division of Cardiology, Beverly Hills, California
    • Westside Medical Imaging, Beverly Hills, California.
    • ,
  • Shervin Eshaghian, MD

      Affiliations

    • Department of Internal Medicine, Cedars-Sinai Medical Center, Beverly Hills, California
    • ,
  • Ashkan L. Naraghi, MD

      Affiliations

    • Department of Internal Medicine, Cedars-Sinai Medical Center, Beverly Hills, California
    • ,
  • Prediman K. Shah, MD

      Affiliations

    • Division of Cardiology, Beverly Hills, California

Received 21 August 2006 ,Revised 13 December 2006 ,Accepted 13 December 2006.

References 

  1. Haberl R, Becker A, Leber A, Knez A, Becker C, Lang C, et al. Correlation of coronary calcification and angiographically documented stenoses in patients with suspected coronary artery disease: results of 1,764 patients. J Am Coll Cardiol. 2001;37:451–457
  2. Greenland P, LaBree L, Azen SP, Doherty TM, Detrano RC. Coronary artery calcium score combined with Framingham score for risk prediction in asymptomatic individuals. JAMA. 2004;291:210–215
  3. Guerci AD, Spadaro LA, Goodman KJ, Lledo-Perez A, Newstein D, Lerner G, et al. Comparison of electron beam computed tomography scanning and conventional risk factor assessment for the prediction of angiographic coronary artery disease. J Am Coll Cardiol. 1998;32:673–679
  4. Kondos GT, Hoff JA, Sevrukov A, Daviglus ML, Garside DB, Devries SS, et al. Electron-beam tomography coronary artery calcium and cardiac events: a 37-month follow-up of 5635 initially asymptomatic low- to intermediate-risk adults. Circulation. 2003;107:2571–2576
  5. Georgiou D, Budoff MJ, Kaufer E, Kennedy JM, Lu B, Brundage BH. Screening patients with chest pain in the emergency department using electron beam tomography: a follow-up study. J Am Coll Cardiol. 2001;38:105–110
  6. Baumgart D, Schmermund A, Goerge G, Haude M, Ge J, Adamzik M, et al. Comparison of electron beam computed tomography with intracoronary ultrasound and coronary angiography for detection of coronary atherosclerosis. J Am Coll Cardiol. 1997;30:57–64
  7. Schmermund A, Baumgart D, Adamzik M, Ge J, Gronemeyer D, Seibel R, et al. Comparison of electron-beam computed tomography and intracoronary ultrasound in detecting calcified and noncalcified plaques in patients with acute coronary syndromes and no or minimal to moderate angiographic coronary artery disease. Am J Cardiol. 1998;81:141–146
  8. Mollet NR, Cademartiri F, van Mieghem CA, Runza G, McFadden EP, Baks T, et al. High-resolution spiral computed tomography coronary angiography in patients referred for diagnostic conventional coronary angiography. Circulation. 2005;112:2318–2323
  9. Leber AW, Knez A, von Ziegler F, Becker A, Nikolaou K, Paul S, et al. Quantification of obstructive and nonobstructive coronary lesions by 64-slice computed tomography: a comparative study with quantitative coronary angiography and intravascular ultrasound. J Am Coll Cardiol. 2005;46:147–154
  10. Fine JJ, Hopkins CB, Ruff N, Newton FC. Comparison of accuracy of 64-slice cardiovascular computed tomography with coronary angiography in patients with suspected coronary artery disease. Am J Cardiol. 2006;97:173–174
  11. Ropers D, Rixe J, Anders K, Kuttner A, Baum U, Bautz W, et al. Usefulness of multidetector row spiral computed tomography with 64- × 0.6-mm collimation and 330-ms rotation for the noninvasive detection of significant coronary artery stenoses. Am J Cardiol. 2006;97:343–348
  12. Raff GL, Gallagher MJ, O’Neill WW, Goldstein JA. Diagnostic accuracy of noninvasive coronary angiography using 64-slice spiral computed tomography. J Am Coll Cardiol. 2005;46:552–557
  13. Hoff JA, Chomka EV, Krainik AJ, Daviglus M, Rich S, Kondos GT. Age and gender distributions of coronary artery calcium detected by electron beam tomography in 35,246 adults. Am J Cardiol. 2001;87:1335–1339
  14. Glagov S, Weisenberg E, Zarins CK, Stankunavicius R, Kolettis GJ. Compensatory enlargement of human atherosclerotic coronary arteries. N Engl J Med. 1987;316:1371–1375
  15. Tuzcu EM, Kapadia SR, Tutar E, Ziada KM, Hobbs RE, McCarthy PM, et al. High prevalence of coronary atherosclerosis in asymptomatic teenagers and young adults: evidence from intravascular ultrasound. Circulation. 2001;103:2705–2710
  16. Leber AW, Becker A, Knez A, von Ziegler F, Sirol M, Nikolaou K, et al. Accuracy of 64-slice computed tomography to classify and quantify plaque volumes in the proximal coronary system: a comparative study using intravascular ultrasound. J Am Coll Cardiol. 2006;47:672–677
  17. Rumberger JA, Brundage BH, Rader DJ, Kondos G. Electron beam computed tomographic coronary calcium scanning: a review and guidelines for use in asymptomatic persons. Mayo Clin Proc. 1999;74:243–252
  18. Halliburton SS, Stillman AE, White RD. Noninvasive quantification of coronary artery calcification: methods and prognostic value. Cleve Clin J Med. 2002;69(suppl 3):S6–S11

 This study was funded internally by Westside Medical Imaging, Beverly Hills, California.

PII: S0002-9149(07)00137-3

doi: 10.1016/j.amjcard.2006.12.026

American Journal of Cardiology
Volume 99, Issue 9 , Pages 1183-1186 , 1 May 2007

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