American Journal of Cardiology
Volume 99, Issue 7 , Pages 903-905 , 1 April 2007

Effects of Atorvastatin on Vitamin D Levels in Patients With Acute Ischemic Heart Disease

  • José L. Pérez-Castrillón, MD

      Affiliations

    • Internal Medicine Department, Río Hortega University Hospital, Faculty of Medicine of Valladolid, Valladolid, Spain
    • Corresponding Author InformationCorresponding author: Tel: 34-983-420-400; fax: 34-983-331-566.
    • ,
  • Gemma Vega, MD

      Affiliations

    • Internal Medicine Department, Río Hortega University Hospital, Faculty of Medicine of Valladolid, Valladolid, Spain
    • ,
  • Laura Abad, MD

      Affiliations

    • Internal Medicine Department, Río Hortega University Hospital, Faculty of Medicine of Valladolid, Valladolid, Spain
    • ,
  • Alberto Sanz, MD

      Affiliations

    • Pediatric Laboratory, Pediatrics-IBGM Department, Faculty of Medicine of Valladolid, Valladolid, Spain
    • ,
  • José Chaves, MD

      Affiliations

    • Pfizer, Madrid, Spain.
    • ,
  • Gonzalo Hernandez, MD

      Affiliations

    • Pfizer, Madrid, Spain.
    • ,
  • Antonio Dueñas, MD

      Affiliations

    • Internal Medicine Department, Río Hortega University Hospital, Faculty of Medicine of Valladolid, Valladolid, Spain

Received 20 September 2006 ,Revised 7 November 2006 ,Accepted 7 November 2006.

References 

  1. Zittermann A. Vitamin D and disease prevention with special reference to cardiovascular disease. Prog Biophys Mol Biol. 2006;92:39–48
  2. Lips P. Vitamin D physiology. Prog Biophys Mol Biol. 2006;92:4–8
  3. Hollick MF. Resurrection of vitamin D deficiency and rickets. J Clin Invest. 2006;116:2062–2072
  4. Wilczek H, Sobra J, Justova V, Ceska R, Juzova Z, Prochazkova R, et al. Iatropathogenic effect of mevacor on vitamin D metabolism. Cas Lek Cesk. 1989;128:1254–1256
  5. Wilzcek H, Sobra J, Ceska R, Justota V, Juzova Z, Prochazkova R, et al. Monitoring plasma levels of vitamin D metabolites in simvastatin therapy in patients with familial hypercholesterolemia. Cas Lek Cesk. 1994;133:727–729
  6. Grimes DS. Are statins analogues of vitamin D?. Lancet. 2006;368:83–85
  7. Zittermann A, Scheleithoff SS, Koerfer R. Vitamin D insufficiency in congestive heart failure: why and what to do about it?. Heart Fail Rev. 2006;11:25–33
  8. Li YC. Vitamin D regulation of the renin-angiotensin system. J Cell Biochem. 2003;88:327–331
  9. Ferrario CM, Strawn WB. Role of the renin-angiotensin-aldosterone system and proinflammatory mediators in cardiovascular disease. Am J Cardiol. 2006;98:121–128
  10. Guryev O, Carvalho RA, Usanov S, Gilep A, Estabrook RW. A pathway for the metabolism of vitamin D3: unique hydroxylated metabolites formed during catalysis with cytochrome P450scc (CYP11A1). Proc Natl Acad Sci USA. 2003;100:14754–14759
  11. Gupta AK, Sexton RC, Rudney H. Effects of vitamin D3 derivatives on cholesterol synthesis and HMG-CoA reductase activity in cultured cells. J Lipid Res. 1989;30:379–386

 This study was supported by Pfizer, Madrid, Spain.

PII: S0002-9149(06)02488-X

doi: 10.1016/j.amjcard.2006.11.036

American Journal of Cardiology
Volume 99, Issue 7 , Pages 903-905 , 1 April 2007

Article Tools

* Image Usage & Resolution