American Journal of Cardiology
Volume 97, Issue 9 , Pages 1365-1369 , 1 May 2006

Factors Associated With Decreased Cerebral Blood Flow in Congestive Heart Failure Secondary to Idiopathic Dilated Cardiomyopathy

  • Bong-Ryong Choi, MD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    • ,
  • Jae Seung Kim, MD

      Affiliations

    • Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    • ,
  • You Jung Yang, MD

      Affiliations

    • Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    • ,
  • Kyoung-Min Park, MD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    • ,
  • Cheol Whan Lee, MD, PhD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    • ,
  • Yong-Hak Kim, MD, PhD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    • ,
  • Myeong-Ki Hong, MD, PhD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    • ,
  • Jae-Kwan Song, MD, PhD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    • ,
  • Seong-Wook Park, MD, PhD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    • ,
  • Seung-Jung Park, MD, PhD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    • ,
  • Jae-Joong Kim, MD, PhD

      Affiliations

    • Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
    • Corresponding Author InformationCorresponding author: Tel: 82-2-3010-3150; fax: 82-2-486-5918.

Received 22 August 2005 ,Revised 14 November 2005 ,Accepted 14 November 2005.

References 

  1. Costanzo MR, Augustine S, Bourge R, Bristow M, O’Connell JB, Driscoll D, et al. Selection and treatment of candidates for heart transplantation (a statement for health professionals from the Committee on Heart Failure and Cardiac Transplantation of the Council on Clinical Cardiology, American Heart Association) . Circulation . 1995;92:3593–3612
  2. Anker SD, Ponikowski P, Varney S, Chua TP, Clark AL, Webb-People KM, et al. Wasting as independent risk factor for mortality in chronic heart failure . Lancet . 1997;349:1050–1053
  3. Zuccalà G, Onder G, Pedone C, Carosella L, Pahor M, Bernabei R, et al. Hypotension and cognitive impairment (selective association in patients with heart failure) . Neurology . 2001;59:1986–1992
  4. Almeida OP , Flicker L . The mind of a failing heart (a systematic review of the association between congestive heart failure and cognitive functioning) . Intern Med J . 2001;31:290–295
  5. Cohen-Solal A , Laperche T , Morvan D , Geneves M , Caveizel B , Courgon R . Prolonged kinetics of recovery of oxygen consumption after maximal graded exercise in patients with chronic heart failure. Analysis with gas exchange measurements and NMR spectroscopy . Circulation . 1995;91:2924–2932
  6. de Groote P , Millaire A , Decoulx E , Nugue O , Guimier P . Ducloux. Kinetics of oxygen consumption during and after exercise in patients with dilated cardiomyopathy. New markers of exercise intolerance with clinical implications . J Am Coll Cardiol . 1996;28:168–175
  7. Matsuda H , Yagishita A , Tsuji S , Hisada K . A quantitative approach to technetium-99m ethyl cysteinate dimer (a comparison with technetium-99m hexamethylpropylene amine oxime) . Eur J Nucl Med . 1995;22:633
  8. Roman GC . Brain hypoperfusion (a critical factor in vascular dementia) . Neurol Res . 2004;26:454–458
  9. Woo MA, Macey PM, Keens PT, Kumar R, Fonarow GC, Hamilton MA, et al. Functional abnormalities in brain areas that mediate autonomic nervous system control in advanced heart failure . J Card Fail . 2005;11:437–446
  10. Zuccalà G, Pedone C, Cesari M, Onder G, Pahor M, Marzetti E, et al. The effects of cognitive impairment on mortality among hospitalized patients with heart failure . Am J Med . 2003;115:97–103
  11. Wanless RB , Anand IS , Gurden J , Harris P , Poole-Wilson PA . Regional blood flow and hemodynamics in the rabbit with adriamycin cardiomyopathy (effects of isosorbide dinitrate, dobutamine and captopril) . J Pharmacol Exp Ther . 1987;243:1101–1106
  12. Garcia JL , Gomez B , Monge L , Garcia-Villalon AL , Dieguez G . Endothelin action on cerebral circulation in unanesthetized goats . Am J Physiol . 1991;30:581–587
  13. Macrae IM , Robinson MJ , Graham DI , Reid JL , McCulloch J . Endothelin-1 induced reduction in cerebral blood flow (dose dependency, time course, and neuropathological consequences) . J Cereb Blood Flow Metab . 1993;13:276–284
  14. Gruhn N, Larsen F, Boesgaard S, Kundsen GM, Mortensen SA, Thomsen G, et al. Cerebral blood flow in patients with chronic heart failure before and after heart transplantation . Stroke . 2001;32:2530–2533
  15. Tzourio C, Anderson C, Chapman N, Woodward M, Neal B, MacMahon S, et al. Effects of blood pressure lowering with perindopril and indapamide on dementia and cognitive decline in patients with cerebrovascular disease . Arch Intern Med . 2003;163:1069–1075
  16. Fogari R, Mugellini A, Zoppi A, Derosa G, Pasotti C, Fogari E, et al. Influence of losartan and atenolol on memory function in very elderly hypertensive patients . J Hum Hypertens . 2003;17:781–785
  17. Zuccalà G, Onder G, Marzetti E, Monaco MR, Cesari M, Cocchi A, et al. Use of angiotensin-converting enzyme inhibitors and variations in cognitive performance among patients with heart failure . Eur Heart J . 2005;26:226–233
  18. Nishimura R , Tajik AA . Quantitative hemodynamics by Doppler echocardiography (a noninvasive alternative to cardiac catheterization) . Prog Cardiovasc Dis . 1994;36:309–342
  19. Rihal C , Nishimura R , Hatle L , Bailey K , Tajik A . Systolic and diastolic dysfunction in patients with clinical diagnosis of dilated cardiomyopathy (relation to symptoms and prognosis) . Circulation . 1994;90:2772–2779
  20. Giannuzzi P , Temporelli P , Bosimini E . Independent and incremental prognostic value of Doppler-derived mitral deceleration time of early filling in both symptomatic and asymptomatic patients with left ventricular dysfunction . J Am Coll Cardiol . 1996;28:383–390
  21. Struthers A . Further defining the role for natriuretic peptide levels in clinical practice . Eur Heart J . 1999;20:712–714
  22. Fruhwald F, Fahrleitner A, Watzinger N, Fruhwald S, Dobnig H, Schumacher M, et al. Natriuretic peptides in patients with diastolic dysfunction due to idiopathic dilated cardiomyopathy . Eur Heart J . 1999;20:1415–1423
  23. Yu CM, Sanderson JE, Shum IOL, Chan S, Yeung LY, Hung YT, et al. Diastolic dysfunction and natriuretic peptides in systolic heart failure . Eur Heart J . 1996;17:1694–1702
  24. Fruhwald FM, Fahrleitner A, Watzinger N, Fruhwald S, Dobnig H, Schumacher M, et al. Natriuretic peptides in patients with diastolic dysfunction due to dilated cardiomyopathy . Eur Heart J . 1999;20:1415–1423
  25. Catuzzo B , Ciancamerla F , Bobbio M , Longo M , Trevi GP . In patients with severe systolic dysfunction, only brain natriuretic peptide is related to diastolic restrictive pattern . J Cardiac Fail . 2003;9:303–310
  26. Stelken AM , Younis LT , Jennison SH . Prognostic value of cardiopulmonary exercise testing using percent achieved of predicted peak oxygen uptake for patients with ischemic and dilated cardiomyopathy . J Am Coll Cardiol . 1996;27:345–352
  27. Cohen-Solal A, Barnier P, Pessione F, Seknadji P, Logeart D, Laperche T, et al. Comparison of the long term prognostic value of peak exercise oxygen uptake and peak oxygen pulse in patients with chronic heart failure . Heart . 1997;78:572–576
  28. Hambrecht R, Gielen S, Linke A, Fiehn E, Yu J, Walther C, et al. Effects of exercise training on left ventricular function and peripheral resistance in patients with chronic heart failure (a randomized trial) . JAMA . 2000;283:3095–3101
  29. Patrianakos AP, Parthenakis FI, Papadimitriou EA, Diakakis GF, Tzerakis PG, Nikitovic D, et al. Restrictive filling pattern is associated with increased humoral activation and impaired exercise capacity in dilated cardiomyopathy . Eur J Heart Fail . 2004;6:735–743

 This study was supported by a grant from the Korea Health 21 R&D Project, Ministry of Health & Welfare, Seoul, Korea (0412-CR02-0704-0001).

PII: S0002-9149(06)00165-2

doi: 10.1016/j.amjcard.2005.11.059

American Journal of Cardiology
Volume 97, Issue 9 , Pages 1365-1369 , 1 May 2006

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