American Journal of Cardiology
Volume 96, Issue 10 , Pages 1399-1403 , 15 November 2005

Three-Year Clinical Follow-Up After Strontium-90/Yttrium-90 Beta-Irradiation for the Treatment of In-Stent Coronary Restenosis

  • Verena Baierl, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, Medizinische Klinik und Poliklinik, University Hospital Campus Innenstadt, Munich, Germany
    • ,
  • Simone Baumgartner, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, Medizinische Klinik und Poliklinik, University Hospital Campus Innenstadt, Munich, Germany
    • ,
  • Barbara Pöllinger, MD

      Affiliations

    • Department of Radiation Therapy and Radiation Oncology, Medizinische Klinik und Poliklinik, University Hospital Campus Innenstadt, Munich, Germany
    • ,
  • Marcus Leibig, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, Medizinische Klinik und Poliklinik, University Hospital Campus Innenstadt, Munich, Germany
    • ,
  • Johannes Rieber, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, Medizinische Klinik und Poliklinik, University Hospital Campus Innenstadt, Munich, Germany
    • ,
  • Andreas König, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, Medizinische Klinik und Poliklinik, University Hospital Campus Innenstadt, Munich, Germany
    • ,
  • Florian Krötz, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, Medizinische Klinik und Poliklinik, University Hospital Campus Innenstadt, Munich, Germany
    • ,
  • Hae-Young Sohn, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, Medizinische Klinik und Poliklinik, University Hospital Campus Innenstadt, Munich, Germany
    • ,
  • Uwe Siebert, MD

      Affiliations

    • Harvard Center for Risk Analysis, Harvard School of Public Health, Boston, Massachusetts.
    • ,
  • Wolfgang Haimerl, PhD

      Affiliations

    • Department of Radiation Therapy and Radiation Oncology, Medizinische Klinik und Poliklinik, University Hospital Campus Innenstadt, Munich, Germany
    • ,
  • Eckhart Dühmke, MD

      Affiliations

    • Department of Radiation Therapy and Radiation Oncology, Medizinische Klinik und Poliklinik, University Hospital Campus Innenstadt, Munich, Germany
    • ,
  • Karl Theisen, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, Medizinische Klinik und Poliklinik, University Hospital Campus Innenstadt, Munich, Germany
    • ,
  • Volker Klauss, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, Medizinische Klinik und Poliklinik, University Hospital Campus Innenstadt, Munich, Germany
    • ,
  • Thomas M. Schiele, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, Medizinische Klinik und Poliklinik, University Hospital Campus Innenstadt, Munich, Germany
    • Corresponding Author InformationCorresponding author: Tel: 49-89-5160-2177; fax: 49-89-5160-2152.

Received 9 May 2005 ,Revised 28 June 2005 ,Accepted 28 June 2005.

References 

  1. Bauters C , Banos JL , Van Belle E , McFadden EP , Lablanche JM , Bertrand ME . Six-month angiographic outcome after successful repeat percutaneous intervention for in-stent restenosis . Circulation . 1998;97:318–321
  2. Mahdi NA, Pathan AZ, Harrell L, Leon MN, Lopez J, Butte A, et al. Directional coronary atherectomy for the treatment of Palmaz-Schatz in-stent restenosis . Am J Cardiol . 1998;82:1345–1351
  3. Mehran R, Dangas G, Mintz GS, Waksman R, Abizaid A, Satler LF, et al. Treatment of in-stent restenosis with excimer laser coronary angioplasty versus rotational atherectomy (comparative mechanisms and results) . Circulation . 2000;101:2484–2489
  4. Dietz U, Rupprecht H, de Belder M, Wijns W, Quarles van Ufford MA, Klues HG, et al. Angiographic analysis of the angioplasty versus rotational atherectomy for the treatment of diffuse in-stent restenosis trial (ARTIST) . Am J Cardiol . 2002;90:843–847
  5. Serruys PW, Luijten HE, Beatt KJ, Geuskens R, de Feyter PJ, van den Brand M, et al. Incidence of restenosis after successful coronary angioplasty: a time-related phenomenon. A quantitative angiographic study in 342 consecutive patients at 1, 2, 3, and 4 months . Circulation . 1988;77:361–371
  6. Nobuyoshi M, Kimura T, Nosaka H, Mioka S, Ueno K, Yokoi H, et al. Restenosis after successful percutaneous transluminal coronary angioplasty (serial angiographic follow-up of 229 patients) . J Am Coll Cardiol . 1988;12:616–623
  7. Teirstein PS, Massullo V, Jani S, Popma JJ, Mintz GS, Russo RJ, et al. Catheter-based radiotherapy to inhibit restenosis after coronary stenting . N Engl J Med . 1997;336:1697–1703
  8. Waksman R, White RL, Chan RC, Bass BG, Geirlach L, Mintz GS, et al  Intracoronary gamma-radiation therapy after angioplasty inhibits recurrence in patients with in-stent restenosis . Circulation . 2000;101:2165–2171
  9. Leon MB, Teirstein PS, Moses JW, Tripuraneni P, Lansky AJ, Jani S, et al. Localized intracoronary gamma-radiation therapy to inhibit the recurrence of restenosis after stenting . N Engl J Med . 2001;344:250–256
  10. Waksman R, Bhargava B, White L, Chan RC, Mehran R, Lansky AJ, et al. Intracoronary beta-radiation therapy inhibits recurrence of in-stent restenosis . Circulation . 2000;101:1895–1898
  11. Popma JJ, Suntharalingam M, Lansky AJ, Heuser RR, Speiser B, Teirstein PS, et al  Randomized trial of 90Sr/90Y beta-radiation versus placebo control for treatment of in-stent restenosis . Circulation . 2002;106:1090–1096
  12. Teirstein PS, Massullo V, Jani S, Popma JJ, Russo RJ, Schatz RA, et al. Three-year clinical and angiographic follow-up after intracoronary radiation (results of a randomized clinical trial) . Circulation . 2000;101:360–365
  13. Grise MA, Massullo V, Jani S, Popma JJ, Russo RJ, Schatz RA, et al. Five-year clinical follow-up after intracoronary radiation (results of a randomized clinical trial) . Circulation . 2002;105:2737–2740
  14. Waksman R, Ajani AE, White RL, Pinnow E, Mehran R, Bui AB, et al  Two-year follow-up after beta and gamma intracoronary radiation therapy for patients with diffuse in-stent restenosis . Am J Cardiol . 2001;88:425–428
  15. Waksman R, Ajani AE, White RL, Chan R, Bass B, Pichard AD, et al. Five-year follow-up after intracoronary gamma radiation therapy for in-stent restenosis . Circulation . 2004;109:340–344
  16. Silber S, Popma JJ, Sunthalaringam M, Lansky AJ, Heuser RR, Speiser B, et al  Two-year clinical follow-up of 90Sr/90Y beta-radiation versus placebo control for the treatment of in-stent restenosis . Am Heart J . 2005;149:689–694
  17. Schiele TM, Pollinger B, Kantlehner R, Rieber J, Konig A, Seelig V, et al. Evolution of angiographic restenosis rate and late lumen loss after intracoronary beta radiation for in-stent restenotic lesions . Am J Cardiol . 2004;93:836–842
  18. Waksman R, Robinson KA, Crocker IR, Wang C, Gravanis MB, Cipolla GD, et al. Intracoronary low-dose beta-irradiation inhibits neointima formation after coronary artery balloon injury in the swine restenosis model . Circulation . 1995;92:3025–3031
  19. Carter AJ , Scott D , Bailey L , Hoopes T , Jones R , Virmani R . Dose-response effects of 32P radioactive stents in an atherosclerotic porcine coronary model . Circulation . 1999;100:1548–1554
  20. Coussement PK, de Leon H, Ueno T, Salame MY, King SB, Chronos NA, et al. Intracoronary beta-radiation exacerbates long-term neointima formation in balloon-injured pig coronary arteries . Circulation . 2001;104:2459–2464
  21. Wiedermann JG , Marboe C , Amols H , Schwartz A , Weinberger J . Intracoronary irradiation markedly reduces restenosis after balloon angioplasty in a porcine model . J Am Coll Cardiol . 1994;23:1491–1498
  22. Bonan R . The role of brachytherapy and cutting balloon angioplasty in the current treatment of stent restenosis . Coron Artery Dis . 2004;15:319–325

PII: S0002-9149(05)01344-5

doi: 10.1016/j.amjcard.2005.06.087

American Journal of Cardiology
Volume 96, Issue 10 , Pages 1399-1403 , 15 November 2005

Article Tools

* Image Usage & Resolution