American Journal of Cardiology
Volume 96, Issue 5 , Pages 617-621 , 1 September 2005

Relation of C-Reactive Protein and One-Year Survival After Acute Myocardial Infarction With Versus Without Statin Therapy

  • Kunihiro Kinjo, MD

      Affiliations

    • Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan
    • ,
  • Hiroshi Sato, MD

      Affiliations

    • Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan
    • Corresponding Author InformationCorresponding author: Tel.: 81-6-6879-6612; fax: 81-6-6879-6613.
    • ,
  • Yasuhiko Sakata, MD

      Affiliations

    • Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan
    • ,
  • Daisaku Nakatani, MD

      Affiliations

    • Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan
    • ,
  • Hiroya Mizuno, MD

      Affiliations

    • Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan
    • ,
  • Masahiko Shimizu, MD

      Affiliations

    • Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan
    • ,
  • Masami Nishino, MD

      Affiliations

    • Osaka Rosai Hospital, Sakai, Japan
    • ,
  • Hiroshi Ito, MD

      Affiliations

    • Sakurabashi Watanabe Hospital, Osaka, Japan
    • ,
  • Jun Tanouchi, MD

      Affiliations

    • Osaka Rosai Hospital, Sakai, Japan
    • ,
  • Shinsuke Nanto, MD

      Affiliations

    • Kansai Rosai Hospital, Amagasaki, Japan.
    • ,
  • Masatsugu Hori, MD

      Affiliations

    • Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan
    • ,
  • Osaka Acute Coronary Insufficiency Study (OACIS) Group

Received 3 January 2005 ,Revised 11 April 2005 ,Accepted 11 April 2005.

References 

  1. Kinjo K, Sato H, Ohnishi Y, Hishida E, Nakatani D, Mizuno H, et al. Impact of high-sensitivity C-reactive protein on predicting long-term mortality of acute myocardial infarction . Am J Cardiol . 2003;91:931–935
  2. Kinjo K, Sato H, Sato H, Ohnishi Y, Hishida E, Nakatani D, et al. Prognostic significance of atrial fibrillation/atrial flutter in patients with acute myocardial infarction treated with percutaneous coronary intervention . Am J Cardiol . 2003;92:1150–1154
  3. Ohnishi Y, Tanaka T, Yamada R, Suematsu K, Minami M, Fujii K, et al  Identification of 187 single nucleotide polymorphisms (SNPs) among 41 candidate genes for ischemic heart disease in the Japanese population . Hum Genet . 2000;106:288–292
  4. Ozaki K, Inoue K, Sato H, Iida A, Ohnishi Y, Sekine A, et al. Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro . Nature . 2004;429:72–75
  5. Ridker PM, Rifai N, Clearfield M, Downs JR, Weis SE, Miles JS, et al. Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events . N Engl J Med . 2001;344:1959–1965
  6. Ridker PM, Rifai N, Pfeffer MA, Sacks FM, Moye LA, Goldman S, et al. Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels . Circulation . 1998;98:839–844
  7. Walter DH, Fichtlscherer S, Britten MB, Rosin P, Auch-Schwelk W, Schachinger V, et al. Statin therapy, inflammation and recurrent coronary events in patients following coronary stent implantation . J Am Coll Cardiol . 2001;38:2006–2012
  8. Libby P , Ridker PM , Maseri A . Inflammation and atherosclerosis . Circulation . 2002;105:1135–1143
  9. Ridker PM, Cannon CP, Morrow D, Rifai N, Rose LM, McCabe CH, et al. Pravastatin or atorvastatin evaluation, infection therapy—Thrombolysis In Myocardial Infarction I. C-reactive protein levels and outcomes after statin therapy . N Engl J Med . 2005;352:20–28
  10. Nissen SE, Tuzcu EM, Schoenhagen P, Crowe T, Sasiela WJ, Tsai J, et al. Reversal of atherosclerosis with aggressive lipid lowering I. Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease . N Engl J Med . 2005;352:29–38

 This work was supported by a Grant-in-Aid for Scientific Research (C)(2) (no. 15590743) from the Japan Society for the Promotion of Science, Tokyo, Japan, and by research funds from the Japan Arteriosclerosis Prevention Fund, Tokyo, Japan.

PII: S0002-9149(05)00926-4

doi: 10.1016/j.amjcard.2005.04.030

American Journal of Cardiology
Volume 96, Issue 5 , Pages 617-621 , 1 September 2005

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