American Journal of Cardiology
Volume 96, Issue 5 , Pages 617-621 , 1 September 2005

Relation of C-Reactive Protein and One-Year Survival After Acute Myocardial Infarction With Versus Without Statin Therapy

  • Kunihiro Kinjo, MD

      Affiliations

    • Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan
    • ,
  • Hiroshi Sato, MD

      Affiliations

    • Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan
    • Corresponding Author InformationCorresponding author: Tel.: 81-6-6879-6612; fax: 81-6-6879-6613.
    • ,
  • Yasuhiko Sakata, MD

      Affiliations

    • Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan
    • ,
  • Daisaku Nakatani, MD

      Affiliations

    • Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan
    • ,
  • Hiroya Mizuno, MD

      Affiliations

    • Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan
    • ,
  • Masahiko Shimizu, MD

      Affiliations

    • Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan
    • ,
  • Masami Nishino, MD

      Affiliations

    • Osaka Rosai Hospital, Sakai, Japan
    • ,
  • Hiroshi Ito, MD

      Affiliations

    • Sakurabashi Watanabe Hospital, Osaka, Japan
    • ,
  • Jun Tanouchi, MD

      Affiliations

    • Osaka Rosai Hospital, Sakai, Japan
    • ,
  • Shinsuke Nanto, MD

      Affiliations

    • Kansai Rosai Hospital, Amagasaki, Japan.
    • ,
  • Masatsugu Hori, MD

      Affiliations

    • Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan
    • ,
  • Osaka Acute Coronary Insufficiency Study (OACIS) Group

Received 3 January 2005 ,Revised 11 April 2005 ,Accepted 11 April 2005.

  • Image Result

    Kaplan-Meier survival curves show that 1-year mortality rate was lower in patients who received statin therapy than in those who did not (1.4% vs 3.4%, log-rank test, p <0.001).

    Kaplan-Meier survival curves show that 1-year mortality rate was lower in patients who received statin therapy than in those who did not (1.4% vs 3.4%, log-rank test, p <0.001).

  • Image Result

    Kaplan-Meier survival curves for 1-year mortality rate according to prescription of statin by subgroup: (A) Serum CRP level <2.9 mg/L and (B) CRP level ≥2.9 mg/L.

    Kaplan-Meier survival curves for 1-year mortality rate according to prescription of statin by subgroup: (A) Serum CRP level <2.9 mg/L and (B) CRP level ≥2.9 mg/L.

  • Image Result

    HRs for 1-year mortality after AMI according to high versus low CRP level and prescription versus nonprescription of a statin. Adjustments were made for age, gender, body mass index, diabetes mellitus

    HRs for 1-year mortality after AMI according to high versus low CRP level and prescription versus nonprescription of a statin. Adjustments were made for age, gender, body mass index, diabetes mellitus, hypertension, cholesterol level, current smoking, previous myocardial infarction, previous cerebrovascular disease, revascularization, Killip’s class ≥II, anterior wall myocardial infarction, and use of angiotensin-converting enzyme inhibitors, β blockers, and antiplatelet agents.

 This work was supported by a Grant-in-Aid for Scientific Research (C)(2) (no. 15590743) from the Japan Society for the Promotion of Science, Tokyo, Japan, and by research funds from the Japan Arteriosclerosis Prevention Fund, Tokyo, Japan.

PII: S0002-9149(05)00926-4

doi: 10.1016/j.amjcard.2005.04.030

American Journal of Cardiology
Volume 96, Issue 5 , Pages 617-621 , 1 September 2005

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