American Journal of Cardiology
Volume 95, Issue 2 , Pages 304-307, 15 January 2005

Relation between effects of adenosine on brachial artery reactivity and perfusion pattern in patients with known or suspected coronary artery disease

  • Deval Mehta, MD

      Affiliations

    • Division of Cardiovascular Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama
    • ,
  • Gurpreet Baweja, MD

      Affiliations

    • Sarver Heart Institute, Tucson, Arizona
    • ,
  • Rajesh Venkataraman, MD

      Affiliations

    • Division of Cardiovascular Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama
    • ,
  • Gilbert J. Zoghbi, MD

      Affiliations

    • Division of Cardiovascular Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama
    • ,
  • Thein Htay, MD

      Affiliations

    • Division of Cardiovascular Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama
    • ,
  • Jaekyeong Heo, MD

      Affiliations

    • Division of Cardiovascular Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama
    • ,
  • Navin C. Nanda, MD

      Affiliations

    • Division of Cardiovascular Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama
    • ,
  • Ami E. Iskandrian, MD

      Affiliations

    • Division of Cardiovascular Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama
    • Corresponding Author InformationDr. Iskandrian's address is: University of Alabama at Birmingham, 318 LHRB, 1900 University Blvd., Birmingham, Alabama 35294-0006

Received 28 June 2004; accepted 26 August 2004.

This study examined the changes in brachial artery diameter and flow velocity in response to intravenous adenosine and compared the results to cuff occlusion and single-photon emission computed tomographic (SPECT) images. The change in diameter was less with adenosine than with cuff occlusion. There was no correlation between the presence of abnormal SPECT images and the responses to adenosine or cuff occlusion in either diameter or flow velocity.

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 This study was supported by an unrestricted grant from Fujisawa Healthcare, Inc., Deerfield, Illinois.

PII: S0002-9149(04)01550-4

doi:10.1016/j.amjcard.2004.08.100

American Journal of Cardiology
Volume 95, Issue 2 , Pages 304-307, 15 January 2005

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